ChemicalBook > CAS DataBase List > [(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone

[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone

Product Name
[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone
CAS No.
1382481-79-9
Chemical Name
[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone
Synonyms
ML289;VU0463597;ML289, 10 mM in DMSO;(R)-(3-(Hydroxymethyl)piperidin-1-yl)(4-((4-methoxyphenyl)ethynyl)phenyl)methanone;(3R)-3-(Hydroxymethyl)-1-piperidinyl]{4-[(4-methoxyphenyl)ethyny l]phenyl}methanone;[(3R)-3-(Hydroxymethyl)-1-pipridinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone;[(3R)-3-(hydroxymethyl)piperidin-1-yl]-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone;[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone;Methanone, [(3R)-3-(hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-
CBNumber
CB22652153
Molecular Formula
C22H23NO3
Formula Weight
349.42
MOL File
1382481-79-9.mol
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[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone Property

storage temp. 
2-8°C
solubility 
DMSO: soluble10mg/mL, clear
form 
powder
color 
white to beige
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0555
Product name
ML289
Purity
≥98% (HPLC)
Packaging
25mg
Price
$392
Updated
2022/05/15
Cayman Chemical
Product number
15195
Product name
ML-289
Purity
≥98%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
15195
Product name
ML-289
Purity
≥98%
Packaging
5mg
Price
$90
Updated
2024/03/01
Cayman Chemical
Product number
15195
Product name
ML-289
Purity
≥98%
Packaging
10mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
15195
Product name
ML-289
Purity
≥98%
Packaging
25mg
Price
$353
Updated
2024/03/01
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[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone Chemical Properties,Usage,Production

Uses

ML-289 is a novel CNS-penetrant, metabotropic glutamate receptor 3 (mGlu3) NAM probe derived from mGlu5 PAM (1).

IC 50

mGluR3: 0.66 μM (IC50)

storage

+4°C

[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone Preparation Products And Raw materials

Raw materials

Preparation Products

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[(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone Suppliers

Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4769
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
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Shanghai Rechem science Co., Ltd.
Tel
021-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2991
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Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
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chaolaichem@foxmail.com
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China
ProdList
12475
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
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Changzhou Chenhong Biotechnology Co., Ltd.
Tel
+86-0519-85788828 +86-13775037613
Email
sales@chemrenpharm.com
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China
ProdList
3934
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Wuxi Donghe Pharmaceutical Technology Co., Ltd.
Tel
63313187 15358055255
Fax
QQ:63313187
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Country
China
ProdList
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Energy Chemical
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021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
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1382481-79-9, [(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanoneRelated Search:


  • [(3R)-3-(Hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-methanone
  • ML289
  • VU0463597
  • [(3R)-3-(hydroxymethyl)piperidin-1-yl]-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone
  • [(3R)-3-(Hydroxymethyl)-1-pipridinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone
  • Methanone, [(3R)-3-(hydroxymethyl)-1-piperidinyl][4-[2-(4-methoxyphenyl)ethynyl]phenyl]-
  • (3R)-3-(Hydroxymethyl)-1-piperidinyl]{4-[(4-methoxyphenyl)ethyny l]phenyl}methanone
  • ML289, 10 mM in DMSO
  • (R)-(3-(Hydroxymethyl)piperidin-1-yl)(4-((4-methoxyphenyl)ethynyl)phenyl)methanone
  • 1382481-79-9