ChemicalBook > CAS DataBase List > D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
- Product Name
- D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
- CAS No.
- 103404-90-6
- Chemical Name
- D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT
- Synonyms
- d-α-hydroxyglutaric acid disodium salt;sodiuM 2-hydroxypentanedioate;(r)-2-hydroxypentanedioic acid;Disodium (R)-2-hydroxyglutarate;(2R)-2-Hydroxypentanedioic acid;D-A-HYDROXYGLUTARIC ACID DISODIUM;SodiuM (R)-2-hydroxypentanedioate;D-α-Hydroxyglutaric acid disodium;isodium,(2R)-2-hydroxypentanedioate;D-α-Hydroxyglutaricaciddisodiumsalt
- CBNumber
- CB2266017
- Molecular Formula
- C5H9NaO5
- Formula Weight
- 172.11
- MOL File
- 103404-90-6.mol
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D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Property
- Melting point:
- >291°C (dec.)
- storage temp.
- -20°C
- solubility
- PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
- optical activity
- [α]/D 8.5±1.5°, c = 1 in NaOH
- Water Solubility
- Soluble to 100 mM in water
- BRN
- 5318041
- Stability:
- Hygroscopic
- InChIKey
- DZHFTEDSQFPDPP-HWYNEVGZSA-L
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Safety
- WGK Germany
- 3
- HS Code
- 29181990
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 16859
- Product name
- D-α-Hydroxyglutaric acid disodium salt
- Purity
- ≥98.0% (GC)
- Packaging
- 10mg
- Price
- $78.6
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 16859
- Product name
- D-α-Hydroxyglutaric acid disodium salt
- Purity
- ≥98.0% (GC)
- Packaging
- 50mg
- Price
- $316
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 11605
- Product name
- D-α-Hydroxyglutaric Acid (sodium salt)
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $49
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 11605
- Product name
- D-α-Hydroxyglutaric Acid (sodium salt)
- Purity
- ≥95%
- Packaging
- 25mg
- Price
- $109
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- H8378
- Product name
- D-α-Hydroxyglutaric acid disodium salt
- Purity
- ≥95% (GC)
- Packaging
- 100mg
- Price
- $519
- Updated
- 2024/03/01
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D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Chemical Properties,Usage,Production
Description
D-α-Hydroxyglutaric Acid (D-2-HG) is an α-hydroxy acid that is over-produced in the human neurometabolic disease D-2-hydroxyglutaric aciduria (D-2-HGA). It is normally synthesized from 2-ketoglutarate (2-KG) by hydroxyacid-oxoacid transhydrogenase (HOT), although defects in HOT are not known to be associated with D-2-HGA. Instead, type I D-2-HGA involves mutations in D-2-hydroxyglutarate dehydrogenase, which converts D-2-HG back to 2-KG. Type II D-2-HGA results from gain-of-function mutations in isocitrate dehydrogenase 2, causing it to supplement HOT in converting 2-KG to D-2-HG. In bacteria, this α-hydroxy acid may be synthesized from oxalate and propionyl-coenzyme A by an α-hydroxyglutaric acid synthetase.
Chemical Properties
Pale Orange Solid
Uses
A potential inhibitor of glutamate carboxypeptidase.
Biochem/physiol Actions
Biomarker for inborn errors of metabolism and cancer
storage
Store at -20°C
D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT manufacturers
Career Henan Chemical Co
- Product
- D-2-HYDROXYPENTANEDIOIC ACID DISODIUM SALT 103404-90-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 500kg/month
- Release date
- 2019-08-01
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