ChemicalBook > CAS DataBase List > 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one

1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one

Product Name
1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one
CAS No.
1469337-95-8
Chemical Name
1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one
Synonyms
105456;CS-1676;K-Ras G12C-IN-12;G12C INHIBITOR 12;K RAS INHIBITOR 12;K-Ras(G12C) inhibitor;K-Ras(G12C) inhibitor 12;K RAS INHIBITOR 12; G12C INHIBITOR 12;1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)amino]acetyl]-1-piperazinyl]-2-propen-1-one;1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one
CBNumber
CB22684363
Molecular Formula
C15H17ClIN3O3
Formula Weight
449.67
MOL File
1469337-95-8.mol
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1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Property

Boiling point:
680.2±55.0 °C(Predicted)
Density 
1.736±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
≥8.98 mg/mL in DMSO with gentle warming
form 
solid
pka
8.60±0.50(Predicted)
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20118
Product name
K-Ras(G12C) Inhibitor 12
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
20118
Product name
K-Ras(G12C) Inhibitor 12
Purity
≥95%
Packaging
5mg
Price
$145
Updated
2024/03/01
Cayman Chemical
Product number
20118
Product name
K-Ras(G12C) Inhibitor 12
Purity
≥95%
Packaging
10mg
Price
$275
Updated
2024/03/01
Cayman Chemical
Product number
20118
Product name
K-Ras(G12C) Inhibitor 12
Purity
≥95%
Packaging
25mg
Price
$571
Updated
2024/03/01
ApexBio Technology
Product number
B4876
Product name
K-Ras(G12C)inhibitor12
Packaging
2mg
Price
$126
Updated
2021/12/16
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1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Chemical Properties,Usage,Production

References

[1]. ostrem jm1, peters u, sos ml, et al. k-ras(g12c) inhibitors allosterically control gtp affinity and effector interactions. nature, 2013, 503(7477): 548-551.

1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Suppliers

Shanghai Boyle Chemical Co., Ltd.
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86-21-57758967
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sales@boylechem.com
Country
China
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ChemShuttle, Inc.
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0510-83588313-802 18800520310;
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sales@chemshuttle.com
Country
China
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ShangHai YuanYe Biotechnology Co., Ltd.
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021-61312847 13636370518
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021-55068248
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shyysw007@163.com
Country
China
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4940
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Haoyuan Chemexpress Co., Ltd.
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021-58950125
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(86) 21-58955996
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info@chemexpress.com
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China
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AdooQ BioScience, LLC
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+1 (866) 930-6790
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+1 (866) 333-9607
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info@adooq.com
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United States
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ShangHai KenEn Chemical Technology Co., Ltd.
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13120367189
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021-50315529
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mychess007@163.com
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China
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AdooQ Bioscience CHINA
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025-58849295 18951903616;
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025-68650336
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China
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Shanghai Synchem Pharma Co., ltd
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21-619849051-1 18521059765
Email
synchempharma@aliyun.com
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China
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Yancheng KangdiSen Pharmaceutical Co., Ltd.
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13812573443
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tongbenwan22@163.com
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China
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Pharmacodia (Beijing) Co.,Ltd
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+86-400-851-9921
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+86-10-82826195
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1469337-95-8, 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-oneRelated Search:


  • 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one
  • 2-Propen-1-one, 1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)aMino]acetyl]-1-piperazinyl]-
  • K-Ras G12C-IN-12
  • 105456
  • CS-1676
  • G12C INHIBITOR 12
  • K RAS INHIBITOR 12
  • K RAS INHIBITOR 12; G12C INHIBITOR 12
  • K-Ras(G12C) inhibitor 12
  • 1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)amino]acetyl]-1-piperazinyl]-2-propen-1-one
  • 1-[4-[2-(4-chloro-2-hydroxy-5-iodoanilino)acetyl]piperazin-1-yl]prop-2-en-1-one k-ras(g12c)inhibitor6
  • K-Ras(G12C) inhibitor
  • 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one USP/EP/BP
  • Apoptosis,K-Ras(G-12C) inhibitor 12,inhibit,Inhibitor,Ras,KRas(G12C) inhibitor 12,K-Ras(G12C) inhibitor 12,K Ras(G12C) inhibitor 12
  • 1469337-95-8
  • C15H17ClIN3O3
  • Inhibitors