1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one

Product Name: 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one
CAS No.: 1469337-95-8
Chemical Name: 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one
Synonyms: 105456;CS-1676;K-Ras G12C-IN-12;G12C INHIBITOR 12;K RAS INHIBITOR 12;K-Ras(G12C) inhibitor;K-Ras(G12C) inhibitor 12;K RAS INHIBITOR 12; G12C INHIBITOR 12;1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)amino]acetyl]-1-piperazinyl]-2-propen-1-one;1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one
CBNumber: CB22684363
Molecular Formula: C15H17ClIN3O3
Formula Weight: 449.67
MOL File: 1469337-95-8.mol

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1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Property

Boiling point:: 680.2±55.0 °C(Predicted)
Density: 1.736±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: ≥8.98 mg/mL in DMSO with gentle warming
form: solid
pka: 8.60±0.50(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20118
Product name: K-Ras(G12C) Inhibitor 12
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 20118
Product name: K-Ras(G12C) Inhibitor 12
Purity: ≥95%
Packaging: 5mg
Price: $145
Updated: 2024/03/01

Cayman Chemical

Product number: 20118
Product name: K-Ras(G12C) Inhibitor 12
Purity: ≥95%
Packaging: 10mg
Price: $275
Updated: 2024/03/01

Cayman Chemical

Product number: 20118
Product name: K-Ras(G12C) Inhibitor 12
Purity: ≥95%
Packaging: 25mg
Price: $571
Updated: 2024/03/01

ChemScene

Product number: CS-5104
Product name: K-Ras(G12C)inhibitor12
Purity: >98.0%
Packaging: 50mg
Price: $900
Updated: 2021/12/16

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1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Chemical Properties,Usage,Production

References

[1]. ostrem jm1, peters u, sos ml, et al. k-ras(g12c) inhibitors allosterically control gtp affinity and effector interactions. nature, 2013, 503(7477): 548-551.

1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Suppliers

China 64 United States 11 Global 75

Shanghai Boyle Chemical Co., Ltd.

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Yancheng KangdiSen Pharmaceutical Co., Ltd.

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1469337-95-8, 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-oneRelated Search:

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1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one

2-Propen-1-one, 1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)aMino]acetyl]-1-piperazinyl]-

K-Ras G12C-IN-12

105456

CS-1676

G12C INHIBITOR 12

K RAS INHIBITOR 12

K RAS INHIBITOR 12; G12C INHIBITOR 12

K-Ras(G12C) inhibitor 12

1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)amino]acetyl]-1-piperazinyl]-2-propen-1-one

1-[4-[2-(4-chloro-2-hydroxy-5-iodoanilino)acetyl]piperazin-1-yl]prop-2-en-1-one k-ras(g12c)inhibitor6

K-Ras(G12C) inhibitor

1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one USP/EP/BP

Apoptosis,K-Ras(G-12C) inhibitor 12,inhibit,Inhibitor,Ras,KRas(G12C) inhibitor 12,K-Ras(G12C) inhibitor 12,K Ras(G12C) inhibitor 12

1469337-95-8

C15H17ClIN3O3

Inhibitors