ChemicalBook > CAS DataBase List > 3,5-Dimethoxyphenol

3,5-Dimethoxyphenol

Product Name
3,5-Dimethoxyphenol
CAS No.
500-99-2
Chemical Name
3,5-Dimethoxyphenol
Synonyms
Phenol, 3,5-dimethoxy-;NSC 70955;Taxicatigenin;3,5-DIMETHOXYPHENOL;3,5-Dimethoxyphenol>3,5-DiMethoxyphenol 99%;3,5-Dimethoxyphenol,97%;DIMETHOXYPHENOL, 3,5-(P);Phloroglucinol Impurity 24;Phloroglucin dimethyl ether
CBNumber
CB2268778
Molecular Formula
C8H10O3
Formula Weight
154.16
MOL File
500-99-2.mol
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3,5-Dimethoxyphenol Property

Melting point:
40-43 °C (lit.)
Boiling point:
172-175 °C/17 mmHg (lit.)
Density 
1.1690 (rough estimate)
refractive index 
1.4745 (estimate)
Flash point:
173 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka
pK1:9.345 (25°C)
form 
Liquid
color 
Clear colorless to orange-red to pale pink-brownish
Water Solubility 
Soluble in methanol, ethanol, benzene, water (slightly), and chloroform.
Sensitive 
Air & Light Sensitive
BRN 
1239156
InChIKey
XQDNFAMOIPNVES-UHFFFAOYSA-N
LogP
1.640
CAS DataBase Reference
500-99-2(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 3,5-dimethoxy-(500-99-2)
EPA Substance Registry System
Phenol, 3,5-dimethoxy- (500-99-2)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
F 
10
Hazard Note 
Irritant
HS Code 
29095090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
132632
Product name
3,5-Dimethoxyphenol
Purity
99%
Packaging
10g
Price
$106
Updated
2024/03/01
Sigma-Aldrich
Product number
132632
Product name
3,5-Dimethoxyphenol
Purity
99%
Packaging
50g
Price
$165
Updated
2024/03/01
TCI Chemical
Product number
P0320
Product name
3,5-Dimethoxyphenol
Purity
>98.0%(GC)
Packaging
25g
Price
$149
Updated
2024/03/01
TCI Chemical
Product number
P0320
Product name
3,5-Dimethoxyphenol
Purity
>98.0%(GC)
Packaging
100g
Price
$447
Updated
2024/03/01
Alfa Aesar
Product number
B22283
Product name
3,5-Dimethoxyphenol, 98%
Packaging
10g
Price
$76.65
Updated
2024/03/01
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3,5-Dimethoxyphenol Chemical Properties,Usage,Production

Chemical Properties

slightly pink to yellow crystalline powder

Uses

3,5-dimethoxyphenol is a marker for poisoning from Taxus baccata.

Uses

3,5-Dimethoxyphenol is a phenol derivative as antinitrosating agent.

Definition

ChEBI: 3,5-Dimethoxyphenol is a member of methoxybenzenes and a member of phenols.

Synthesis

Ethanethiol (1.25g, 1.5 ml, 0.02 mole) dissolved in N, N- dimethyl-formamide (20 ml) is added to a suspension of sodium hydride (1 g of 50%oil dispersion) in dry DMF (10 ml) under an atmosphere of nitrogen. The mixture is stirred for 5 min under anhydrous conditions. A solution of phloroglucinol trimethyl ether (1.14) (1 g,0.006 moles) in dry DMF (10 ml)is added, and the mixture is refluxed for 3 hr. The reaction mixture is cooled and acidified with hydrochloric acid (10%). It is extracted with ether(3 x 50 ml). The ether extract is washed with water and extracted with sodium hydroxide solution (5%). The clear alkaline extract is acidified with hydrochloric acid. The mixture is extracted with ether. The ether extract is washed with water, ried (anhydrous sodium sulphate), and drilled. 3,5-Dimethoxyphenol is obtained as an oil. Yield 0.9 g (98.1%).B.p.198-199°/30 mm.

Purification Methods

Purify the phenol by distillation followed by sublimation in a vacuum. [Beilstein 6 IV 7362.]

3,5-Dimethoxyphenol Preparation Products And Raw materials

Raw materials

Preparation Products

4-Hydroxy-2,6-dimethoxybenzaldehyde
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3,5-Dimethoxyphenol Suppliers

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View Lastest Price from 3,5-Dimethoxyphenol manufacturers

Honest Joy Holdings Limited
Product
3,5-Dimethoxyphenol 500-99-2
Price
US $0.00/KG
Min. Order
1KG
Purity
97.0%
Supply Ability
100 tons
Release date
2022-02-18
Career Henan Chemical Co
Product
3,5-Dimethoxyphenol 500-99-2
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10MT
Release date
2018-12-21

500-99-2, 3,5-DimethoxyphenolRelated Search:

2-Ethoxyphenol Dimethyl sulfate Metformin Diphenyldimethoxysilane 1,1-Dimethoxyethane Phloroglucinol Dimethyl carbonate Dimethyl sulfoxide Dimethyl sulfide 3-Methoxyphenol Dimethyldimethoxysilane N,N-Dimethylformamide Guaiacol ETHANE Dimethyl fumarate Dacthal Dimethyl ether Dimethyl sebacate

  • PHLOROGLUCINOL DIMETHYL ETHER
  • 3,5-DIMETHOXYPHENOL
  • 1-Hydroxy-3,5-dimethoxybenzene
  • Taxicatigenin
  • 3,5-Dimethoxy Phenol, 98%min
  • 3,5-DIMETHYOXY PHENYL HYDROXIDE
  • Phenol, 3,5-dimethoxy-
  • Phloroglucinol Impurity 24
  • DIMETHOXYPHENOL, 3,5-(P)
  • 3,5-DiMethoxyphenol 99%
  • Phloroglucin dimethyl ether
  • 3,5-Dimethoxyphenol,97%
  • 3,5-Dimethoxyphenol≥ 98% (GC)
  • 3,5-Dimethoxyphenol,Phloroglucinol dimethyl ether
  • NSC 70955
  • 3,5-Dimethoxyphenol&gt
  • 3,5-Dimethoxyphenol in methanol
  • 500-99-2
  • CH3O2C6H3OH
  • Building Blocks
  • Organic Building Blocks
  • Oxygen Compounds
  • Phenols
  • Aromatic Ethers
  • Building Blocks
  • C6 to C8
  • Chemical Synthesis
  • Organic Building Blocks
  • Oxygen Compounds
  • Phenols