FLLL31

Product Name: FLLL31
CAS No.: 52328-97-9
Chemical Name: FLLL31
Synonyms: FLLL31;FLLL31 >=98% (HPLC);Tetramethylcurcumin;FLLL31;FLLL-31;FLLL 31;Tetramethylcurcumin（FLLL31）;(E,E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethyl-1,6-heptadiene-3,5-dione;(1E,6E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethyl-1,6-heptadiene-3,5-dione;(1E,6E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethylhepta-1,6-diene-3,5-dione;1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4,4-dimethyl-, (1E,6E)-;pancreatic,FLLL-31,domain,FLLL 31,Apoptosis,Inhibitor,STAT,Tetramethylcurcumin,cancer,kinase,Curcumin,Janus,Src,anti-inflammatory,FLLL31,breast,inhibit,homology-2
CBNumber: CB22731058
Molecular Formula: C25H28O6
Formula Weight: 424.49
MOL File: 52328-97-9.mol

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FLLL31 Property

Boiling point:: 594.5±50.0 °C(Predicted)
Density: 1.140±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: ≥10mg/mL
form: powder
color: yellow

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: F9057
Product name: FLLL31
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $134
Updated: 2024/03/01

Sigma-Aldrich

Product number: F9057
Product name: FLLL31
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $436
Updated: 2024/03/01

Usbiological

Product number: 301048
Product name: Tetramethylcurcumin
Packaging: 20mg
Price: $665
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb259527
Product name: Tetramethylcurcumin
Purity: 98%
Packaging: 20mg
Price: $596.7
Updated: 2021/12/16

ChemScene

Product number: CS-0022792
Product name: Tetramethylcurcumin
Packaging: 5mg
Price: $235
Updated: 2021/12/16

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FLLL31 Chemical Properties,Usage,Production

Biological Activity

Tetramethylcurcumin (FLLL31) is derived from curcumin and specifically inhibits phosphorylation of STAT3 by selectively binding to Janus kinase 2 and the STAT3 Src homology 2 domain. Tetramethylcurcumin has anti-inflammatory and anticancer effects.

in vitro

Tetramethylcurcumin (FLLL31; 2.5 and 5 μM; for 24 hours) downregulas STAT3 phosphorylation and DNA-binding activity in MDA-MB-231 breast and PANC-1 pancreatic cancer cells.
Tetramethylcurcumin inhibits cell viability , cell invasion. Tetramethylcurcumin is an effective inhibitor of STAT3 phosphorylation, DNA-binding activity, and transactivation in vitro, leading to the impediment of multiple oncogenic processes and the induction of apoptosis in pancreatic and breast cancer cell lines.

target

STAT3

FLLL31 Preparation Products And Raw materials

Raw materials

Preparation Products

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FLLL31 Suppliers

China 65 United States 5 Global 70

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4940
Advantage: 60

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4566
Advantage: 55

Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
Fax: 021-61350662
Email: sales@zehanbiopharma.com
Country: China
ProdList: 1005
Advantage: 55

Wuhan ChemFaces Biochemical Co., Ltd.

Tel: 18607101326 15172504745
Fax: +86-27-84254680
Email: aileen@chemfaces.com
Country: China
ProdList: 7057
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20806
Advantage: 60

52328-97-9, FLLL31Related Search:

2,2-DIMETHYLTETRAHYDROFURAN Curcumin (3S,5S)-1,7-BIS(4-HYDROXY-3-METHOXYPHENYL)HEPTANE-3,5-DIOL DihydrocurcuMin 5"-MethoxyhexahydrocurcuMin BIS(4-HYDROXYCINNAMOYL)METHANE Tetrahydrocurcumin HEXAHYDROCURCUMIN DEMETHOXYCURCUMIN ASC-J9

FLLL31

Tetramethylcurcumin

(E,E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethyl-1,6-heptadiene-3,5-dione

(1E,6E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethyl-1,6-heptadiene-3,5-dione

FLLL31;FLLL-31;FLLL 31

1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4,4-dimethyl-, (1E,6E)-

FLLL31 >=98% (HPLC)

(1E,6E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethylhepta-1,6-diene-3,5-dione

pancreatic,FLLL-31,domain,FLLL 31,Apoptosis,Inhibitor,STAT,Tetramethylcurcumin,cancer,kinase,Curcumin,Janus,Src,anti-inflammatory,FLLL31,breast,inhibit,homology-2

Tetramethylcurcumin（FLLL31）

52328-97-9