ChemicalBook > CAS DataBase List > Sulfamethazine sodium salt

Sulfamethazine sodium salt

Product Name
Sulfamethazine sodium salt
CAS No.
1981-58-4
Chemical Name
Sulfamethazine sodium salt
Synonyms
sulmet;vesadin;bovibol;Sulfoxine 33;sodiumsulfadimidine;sodiumsulfametazine;SULFADIMIDINE SODIUM;sulfamethazinesodium;sodiumsulfamethazine;sodiumsulfamezathine
CBNumber
CB2284761
Molecular Formula
C12H15N4NaO2S
Formula Weight
302.33
MOL File
1981-58-4.mol
More
Less

Sulfamethazine sodium salt Property

Melting point:
>288°C (dec.)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
H2O: soluble50mg/mL
form 
powder
color 
white to off-white
Water Solubility 
H2O: soluble 50mg/mL
Merck 
14,8915
Stability:
Hygroscopic
InChI
InChI=1S/C12H14N4O2S.Na.H/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11;;/h3-7H,13H2,1-2H3,(H,14,15,16);;
InChIKey
WIVZAHIZHZEEOX-UHFFFAOYSA-N
SMILES
S(C1C=CC(N)=CC=1)(=O)(=O)NC1=NC(C)=CC(C)=N1.[NaH]
CAS DataBase Reference
1981-58-4
EPA Substance Registry System
Benzenesulfonamide, 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-, monosodium salt (1981-58-4)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36
WGK Germany 
3
RTECS 
WO9300000
HS Code 
2933.59.8000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S5637
Product name
Sulfamethazine sodium salt
Purity
≥98%
Packaging
25g
Price
$51.3
Updated
2025/07/31
Sigma-Aldrich
Product number
S5637
Product name
Sulfamethazine sodium salt
Purity
≥98%
Packaging
100g
Price
$74.4
Updated
2025/07/31
TCI Chemical
Product number
S0583
Product name
Sulfamethazine Sodium Salt
Purity
>97.0%(HPLC)(N)
Packaging
25g
Price
$36
Updated
2025/07/31
TCI Chemical
Product number
S0583
Product name
Sulfamethazine Sodium Salt
Purity
>97.0%(HPLC)(N)
Packaging
500g
Price
$191
Updated
2025/07/31
TRC
Product number
S699080
Product name
Sulfamethazine Sodium Salt
Packaging
10g
Price
$70
Updated
2021/12/16
More
Less

Sulfamethazine sodium salt Chemical Properties,Usage,Production

Chemical Properties

White or milky white crystalline powder, odorless or almost odorless, easily soluble in water, slightly soluble in ethanol.

Uses

Antibacterial;Inhibitor of folic acid synthesis

Biological Activity

Sulfamethazine is an antimicrobial sulfur drug th at blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfamethazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It induces CYP3A4 expression and is acetylated by N-acetyltransferase. It exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11. Sulfamethazine is bacteriostatic.

in vivo

Sulfamethazine (80 mg/kg; intravenous injection; healthy female pigs) treatment significantly reduces α, β and AUC0->∞, significantly increases t1/2α, Vd and CIB, and upon a single intramuscular administration of 80 mg/kg of Sulfamethazine the absolute bioavailability in pigs is 1.01[1].

Animal Model:19 healthy female pigs (6-week-old, 4.5-6.2 kg)[1]
Dosage:80 mg/kg
Administration:Intravenous injection (Pharmacokinetic study)
Result:The half-life in distribution phase is 0.23 h and half-lifes in eliminations phase is 9.8 h. α, β and the AUC0->∞ were significantly decreased and t1/2α, Vd and CIB were significantly increased, and the absolute bioavailability in pigs is 1.01.

Sulfamethazine sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Sulfamethazine sodium salt Suppliers

Australia 1 Austria 1 Belgium 1 Brazil 1 Canada 2 China 265 Czech Republic 1 Europe 2 Germany 7 India 14 Japan 1 Mexico 1 Spain 1 Switzerland 2 The Netherlands 4 United Kingdom 4 United States 23 Global 331
-Wugan Pharmaceutical
Tel
13962579006
Email
496322159@qq.com
Country
China
ProdList
16
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768836
Email
1791901229@qq.com
Country
China
ProdList
6950
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
More
Less

View Lastest Price from Sulfamethazine sodium salt manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Sulfamethazine sodium salt 1981-58-4
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%-101%;BP
Supply Ability
1000KGS
Release date
2021-07-05
Sinoway Industrial co., ltd.
Product
Sulfadimidine Sodium 1981-58-4
Price
US $0.00/Kg/Bag
Min. Order
2Kg/Bag
Purity
99% up, High Density
Supply Ability
20 tons
Release date
2021-07-15
Henan Suikang Pharmaceutical Co.,Ltd.
Product
Sulfamethazine sodium salt 1981-58-4
Price
US $0.00/kg
Min. Order
25kg
Purity
＞99%
Supply Ability
10tons
Release date
2024-04-25

1981-58-4, Sulfamethazine sodium saltRelated Search:

Dimethyl phthalate Sodium sulfadiazine Dimethyl sulfoxide Diclofenac sodium Sodium acetate Sulfanilamide Dimethyl carbonate p-Anisidine Sodium chloride N,N-Dimethylformamide 4-Aminobenzoic acid Sulfanilic acid Dimethyl fumarate Aniline Dacthal Dimethyl ether 2-(4-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine Sodium benzoate

  • (n(sup1)-(4,6-dimethyl-2-pyrimidinyl)sulfanilamido)-sodiu
  • 4-amino-n-(4,6-dimethyl-2-pyrimidinyl)-benzenesulfonamidmonosodiumsalt
  • sodiumsulphamezathine
  • sulfamethazinesodium
  • sulmet
  • vesadin
  • 4-AMINO-N-[4,6-DIMETHYL-2-PYRIMIDINYL]BENZENE-SULFONAMIDE SODIUM SALT
  • SULFADIMIDINE SODIUM
  • SULFAMETHAZINE SODIUM SALT
  • Benzenesulfonamide, 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-, monosodium salt
  • SULFADIMIDINE SODIUM(SM2-NA)(NDC:56631-0901)
  • SODIUMSULPHAMETHAZINE
  • 4-Amino-N-(4,6-dimethyl-2-pyrimidyl)benzenesulfonamide Sodium Salt
  • Sulofamethazine Sodium Salt
  • SULFAMETHAZINE SODIUM (SULFADIMIDINE SODIUM)
  • sodium (4-aminophenyl)sulfonyl-(4,6-dimethyl-2-pyrimidinyl)azanide
  • Sulphadimidine Sodium Bp
  • bovibol
  • n(sup1)-(4,6-dimethyl-2-pyrimidinyl)-sulfanilamidmonosodiumsalt
  • salesodicodella2-p-aminobenzensulfonamido-4,6-dimetil-pirimidina
  • sodiumsulfadimidine
  • sodiumsulfametazine
  • sodiumsulfamethazine
  • sodiumsulfamethiazine
  • sodiumsulfamezathine
  • Sodium Sulfamethazine 4-Amino-N-(4,6-dimethyl-2-pyrimidyl)benzenesulfonamide Sodium Salt
  • SulfadiMidine Base(SodiuM)
  • Sulfoxine 33
  • BenzenesulfonaMide,4-aMino-N-(4,6-diMethyl-2-pyriMidinyl)-, sodiuM salt (1:1)
  • SulfaMethazine sodiuM pyriMidine
  • SulfamethazineSodiumSalt&gt
  • Sulfadimethyldiazine Sodium Salt
  • Sulfamethazine sodium salt USP/EP/BP
  • sodium,(4-aminophenyl)sulfonyl-(4,6-dimethylpyrimidin-2-yl)azanide
  • Sulfadimidine SodiumQ: What is Sulfadimidine Sodium Q: What is the CAS Number of Sulfadimidine Sodium Q: What is the storage condition of Sulfadimidine Sodium Q: What are the applications of Sulfadimidine Sodium
  • Sodium ((4-aminophenyl)sulfonyl)(4,6-dimethylpyrimidin-2-yl)amide
  • Sulfadimidine Sodium Powder
  • Sulfadimethyldiazine Sodium Salt|||Sulfamethazine sodium salt
  • Sulfamethazine sodium, 10 mM in DMSO
  • (4-aminophenyl)sulfonyl-(4,6-dimethylpyrimidin-2-yl)azanide
  • 1981-58-4
  • C12H14N4NaO2S
  • C12H13N4NaO2S
  • C12H13N4O2SNa
  • Antibiotics
  • Antibiotics N-S
  • Antibiotics A to Z
  • BioChemical
  • Animal medication
  • Inhibitors
  • API
  • sulfonamides
  • Pharmaceutical intermediate
  • Antibiotics for Research and Experimental Use
  • Biochemistry
  • Sulfonamides (Antibiotics for Research and Experimental Use)
  • 1981-58-4