HEPTENOPHOS Property

Melting point:

25°C

Boiling point:

bp0.001 94-95°

Density 

d420 1.294

vapor pressure 

6.5 x 10^-2 Pa (15 °C)

Flash point:

2 °C

storage temp. 

APPROX 4°C

Water Solubility 

2200 mg l^-1 (20 °C)

form 

liquid

EPA Substance Registry System

Heptenophos (23560-59-0)

Safety

Hazard Codes 

T,N,Xn,F

Risk Statements 

25-50/53-52/53-36-20/21/22-11

Safety Statements 

23-28-37-45-60-61-36/37-26

RIDADR 

3018

WGK Germany 

3

RTECS 

TB8545000

HazardClass 

6.1(b)

PackingGroup 

III

HS Code 

29199000

Hazardous Substances Data

23560-59-0(Hazardous Substances Data)

Toxicity

LD50 orally in rats: 96-117 mg/kg (Hewson)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H312Harmful in contact with skin

H330Fatal if inhaled

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

HEPTENOPHOS Chemical Properties,Usage,Production

Description

Heptenophos is a light brown liquid or crystalline mass. It is soluble in water (2.2 g/L at 20 ?C) and miscible with most organic solvents, except aliphatic hydrocarbons. Log Kow = 2.32. Heptenophos is hydrolyzed in acidic and alkaline media.

Chemical Properties

Pale amber liquid; miscible in most organic solvents; soluble in xylene, acetone, and methanol.

Uses

Heptenophos is used to control sucking pests (primarily aphids) in a wide range of crops. It is also used as an ectoparasiticide to control ticks, lice, mites and fleas in farm animals and pets.

Uses

Insecticide.

Uses

Heptenophos is a pesticide used for fruits and vegetables.

Definition

A nonpersistent contact and systematic phosphate insecticide.

Hazard

Poison; moderately toxic.

Metabolic pathway

Metabolism of heptenophos in soils is by hydrolysis to 7-chloro-bicyclo[3.2.0]hept-2-en-6-one, further transformations of which involve microbially-mediated Baeyer-Villiger oxidations of the cyclobutanone moiety, ring opening of the resultant lactones, dechlorination and dehydrochlorination followed by ultimate mineralisation to CO2 and conversion to unextractable soil-bound residues. In rats, 7-chlorobicyclo[3.2.0]hept-2-en-6-one is further transformed to give the Favorskiirearranged product bicyclo[3.l.0]hex-2-en-6-exo-carboxylic acid as a urinary metabolite.

Metabolism

In rats 90% of heptenophos is excreted in the urine and 6% in the feces as water-soluble metabolites within 6 days after oral administration. In plant (lettuce), it is completely transformed to watersoluble metabolites without accumulation within 4 d. In soil, it is rapidly degraded bymicroorganisms, DT₅₀ (20 ?C) being less than 4 h.

Degradation

Heptenophos is hydrolysed in acidic and alkaline media (PM).

Toxicity evaluation

Acute oral LD₅₀ for rats is 96–121 mg/kg. Inhalation LC50 (4 h) for rats is 0.95 mg/L air. NOEL (2 yr) for rats is 15 mg/kg diet (0.75 mg/kg/d). ADI is 3 μg/kg b.w.