N,N,N',N'-Tetramethyl-1,4-phenylenediamine

Product Name: N,N,N',N'-Tetramethyl-1,4-phenylenediamine
CAS No.: 100-22-1
Chemical Name: N,N,N',N'-Tetramethyl-1,4-phenylenediamine
Synonyms: tl85;TL 85;TMPPD;WursterBlue];wurster’sblue;Wurster's blue;p-Bis(dimethylamino)benzene;Tetramethyl-p-phenyldiamine;1,4-bis(dimethylamino)-benzen;1,4-BIS(DIMETHYLAMINO)BENZENE
CBNumber: CB2300445
Molecular Formula: C10H16N2
Formula Weight: 164.25
MOL File: 100-22-1.mol

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N,N,N',N'-Tetramethyl-1,4-phenylenediamine Property

Melting point:: 49-51 °C(lit.)
Boiling point:: 260 °C(lit.)
Density: 0.9743 (rough estimate)
refractive index: 1.5700 (estimate)
Flash point:: >230 °F
storage temp.: Store below +30°C.
form: powder
pka: 5.92±0.12(Predicted)
color: off-white to gray
Water Solubility: slightly in cold, more in hot water
Sensitive: Air & Light Sensitive
Merck: 14,9228
BRN: 1564025
Stability:: Stable, but may be air or light sensitive. Combustible. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.
CAS DataBase Reference: 100-22-1(CAS DataBase Reference)
NIST Chemistry Reference: 1,4-Benzenediamine, N,N,N',N'-tetramethyl-(100-22-1)
EPA Substance Registry System: N,N,N',N'-Tetramethyl-p-phenylenediamine (100-22-1)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-40-36/37/38
Safety Statements: 28-28A-36-26-22
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 1
RTECS: ST4200000
F: 10
TSCA: Yes
HazardClass: 6.1(a)
PackingGroup: II
HS Code: 29215190
Toxicity: LD50 oral in bird - wild: 23700ug/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.21101
Product name: N,N,N′,N′-Tetramethyl-1,4-phenylenediamine
Purity: for synthesis
Packaging: 5G
Price: $56.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: T7394
Product name: N,N,N′,N′-Tetramethyl-p-phenylenediamine
Purity: 99%, powder
Packaging: 5 g
Price: $115
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.21101
Product name: N,N,N′,N′-Tetramethyl-1,4-phenylenediamine
Purity: for synthesis
Packaging: 25g
Price: $198
Updated: 2025/07/31

Sigma-Aldrich

Product number: T7394
Product name: N,N,N′,N′-Tetramethyl-p-phenylenediamine
Purity: 99%, powder
Packaging: 25 g
Price: $294
Updated: 2025/07/31

Sigma-Aldrich

Product number: T7394
Product name: N,N,N′,N′-Tetramethyl-p-phenylenediamine
Purity: 99%, powder
Packaging: 5g
Price: $112
Updated: 2024/03/01

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N,N,N',N'-Tetramethyl-1,4-phenylenediamine Chemical Properties,Usage,Production

Chemical Properties

purple to brown crystalline powder

Uses

N,N,N',N'-Tetramethyl-p-phenylenediamine is a reducing co-substrate for heme peroxidases. It is used for detection of peroxidases on polyacrylamide gels.

Uses

In the form of the hydrochloride as a reagent in analytical chemistry.

Synthesis Reference(s)

The Journal of Organic Chemistry, 29, p. 488, 1964 DOI: 10.1021/jo01025a506

General Description

Leaflets or a drab green solid.

Air & Water Reactions

N,N,N',N'-Tetramethyl-1,4-phenylenediamine may be sensitive to air and heat. . Insoluble in water.

Reactivity Profile

N,N,N',N'-Tetramethyl-1,4-phenylenediamine can burn in air to give toxic NOx gases . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition N,N,N',N'-Tetramethyl-1,4-phenylenediamine emits toxic fumes. It is an irritant.

Fire Hazard

N,N,N',N'-Tetramethyl-1,4-phenylenediamine is probably combustible.

Safety Profile

Poison by ingestion. Moderatelytoxic by inhalation. Mutation data reported. When heatedto decomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise the amine from pet ether or water. It can be sublimed or dried carefully in a vacuum line, and stored in the dark under nitrogen. It has been recrystallised from its melt. [Beilstein 13 H 74, 13 I 22, 13 II 40, 13 III 111, IV 107.]

N,N,N',N'-Tetramethyl-1,4-phenylenediamine Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N,N',N'-Tetramethyl-1,4-phenylenediamine Suppliers

Belgium 1 China 127 Europe 2 Germany 3 India 6 Japan 2 Switzerland 1 United Kingdom 12 United States 17 Global 171

Shanghai Fengtian Biotechnology Co., Ltd

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View Lastest Price from N,N,N',N'-Tetramethyl-1,4-phenylenediamine manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: N,N,N",N"-Tetramethyl-1,4-phenylenediamine 100-22-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: N,N,N",N"-Tetramethyl-1,4-phenylenediamine 100-22-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

Career Henan Chemical Co

Product: N,N,N',N'-Tetramethyl-1,4-phenylenediamine 100-22-1
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-04

100-22-1, N,N,N',N'-Tetramethyl-1,4-phenylenediamineRelated Search:

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n,n,n’,n’-tetramethyl-4-benzenediamine

N,N,N’,N’-Tetramethyl-benzene-1,4-diamine

n,n,n’,n’-tetramethyl-p-fenylendiamin

N,N,N’,N’-Tetramethyl-p-phenyl

n,n,n’,n’-tetramethyl-p-phenylenediamin

N,N,N',N'-4METH-P-PHENDIA 2HCL

p-Bis(dimethylamino)benzene

p-Phenylenediamine, N,N,N',N'-tetramethyl-

Tetramethyl-p-phenyldiamine

Tetramethyl-p-phenylenediamine

TL 85

tl85

wurster’sblue

Wurster's blue

1,4-Bis(dimethylamino)benzene~Wursters Blue

N,N,N,N-tetramethyl-P-*phenylenediamine free ba

N,N,N',N'-TETRAMETHYL-P-*PHENYLENEDIAMIN E FREE BASE

N,N,N',N'-Tetramethyl-p-phenylenediamine, 98+%

1,4-Benzenediamine, N,N,N,N-tetramethyl-

N,N,N?N?Tetramethyl-p-phenylene- diamine, [1,4-Bis(dimethylamino)benzene

TETRAMETHYLPARA-PHENYLENEDIAMINE

1,4-BenzenediaMine, N1,N1,N4,N4-tetraMethyl-

N,N,N',N'-TetraMethyl-p-phenylenediaMine 99%, powder

TMPPD

WursterBlue]

N,N,N',N'Tetramethyl-p-phenylenediamine≥ 99%(Titration)

N,N,N',N'-Tetramethyl-1,4-phenylenediamine for synthesis

1-N,1-N,4-N,4-N-tetramethylbenzene-1,4-diamine

N1,N1,N4,N4-Tetramethylbenzene-1,4-diamine

N,N,N',N'-TETRAMETHYL-1,4-PHENYLENEDIAMI

4-(Dimethylamino)-N,N-dimethylaniline

100-22-1 C10H16N2 N,N,N',N'-Tetramethyl-1,4-phenylenediamine

-Amino-2-methyl-123H-tetrazole

N,N,N',N'-Tetramethyl-1,4-phenylenediamine

N,N,N,N-Tetramethyl-1,4-phenylenediamine , N,N,N′,N′-Tetramethyl-p-phenylenediamine

N,N,N',N'-Tetramethyl-p-phenylenediamine

N1,N1,N4,N4-Tetramethyl-1,4-benzenediamine

N,N,N′,N′-Tetramethyl-p-phenylenediamine

N,N,N',N'-Tetramethyl-1,4-phenylenediamine

100-22-1

22488-01-9

C6H4NCH322

Building Blocks

Organic Building Blocks

Nitrogen Compounds

Polyamines