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Nudol

Product Name
Nudol
CAS No.
86630-46-8
Chemical Name
Nudol
Synonyms
Nudol;3,4-Dimethoxy-2,7-phenanthrenediol;2,7-dihydroxy-3,4-dimethoxyphenanthrene;Nudol/2,7-dihydroxy-3,4-dimethoxyphenanthrene
CBNumber
CB23051450
Molecular Formula
C16H14O4
Formula Weight
270.27996
MOL File
86630-46-8.mol
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Hazard and Precautionary Statements (GHS)

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Nudol Chemical Properties,Usage,Production

Uses

Nudol is a phenanthrene compound that has anti-cancer activity. Nudol inhibits cell proliferation, induces cell apoptosis. Nudol inhibits MMP-2M and MMP-9 activity (Ki: 988.9 nM, 1.76 μM, respectively). Nudol can be used in the research of cancers, such as osteosarcoma[1][2].

IC 50

MMP-2: 988.9 nM (Ki); MMP-9: 1.76 μM (Ki)

References

[1] Yuying Zhang, et al. Nudol, a phenanthrene derivative from Dendrobium nobile, induces cell cycle arrest and apoptosis and inhibits migration in osteosarcoma cells. Drug Des Devel Ther. 2019 Jul 29;13:2591-2601. DOI:10.2147/DDDT.S180610
[2] Mohammad Al-Amin, et al. Inhibitory Effect of Dioscorea bulbifera Tubers on the Migration of Triple-Negative Breast Cancer Cells. Breast Cancer Cells. Rev. Bras. Farmacogn. 31, 335–341 (2021).

Nudol Preparation Products And Raw materials

Raw materials

Preparation Products

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Nudol Suppliers

Shanghai Winherb Medical Technology Co., Ltd.
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021-38218169 13341702378
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winherb@126.com
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China
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Shanghai Haozhixiang Biotechnology Co., Ltd
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526763801 13301653310
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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Shanghai Uteam Biotechnology Co., Ltd.
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021-36031160 13311776681
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Shanghai Biological Technology Development Co., Ltd.
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Chengdu Push Bio-Technology Co., Ltd.
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028-028-85370565-229-229 18080489829
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Wuhan ChemNorm Biotech Co.,Ltd.
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Chengdu Gupte Biotechnology Co., Ltd.
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86630-46-8, NudolRelated Search:


  • Nudol
  • 3,4-Dimethoxy-2,7-phenanthrenediol
  • 2,7-dihydroxy-3,4-dimethoxyphenanthrene
  • Nudol/2,7-dihydroxy-3,4-dimethoxyphenanthrene
  • 86630-46-8