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TCO-PEG3-Amine

Product Name
TCO-PEG3-Amine
CAS No.
2028288-77-7
Chemical Name
TCO-PEG3-Amine
Synonyms
TCO-PEG3-Amine;TCO-C3-PEG3-C3-amine;(4E)-TCO-C3-PEG3-C3-amine
CBNumber
CB23345119
Molecular Formula
C19H36N2O5
Formula Weight
372.51
MOL File
2028288-77-7.mol
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TCO-PEG3-Amine Property

Boiling point:
506.5±50.0 °C(Predicted)
Density 
1.06±0.1 g/cm3(Predicted)
pka
12.38±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23320
Product name
TCO-C3-PEG3-C3-amine
Purity
95%
Packaging
100mg
Price
$495
Updated
2021/12/16
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TCO-PEG3-Amine Chemical Properties,Usage,Production

Description

TCO-PEG3-amine is a click chemistry crosslinking reagent. It can be used to derivatize NHS activated esters through a stable amide bond or carboxyl groups in the presence of of activators (e.g. EDC, or HATU). TCO enable click chemistry with tetrazine. PEG spacer improves water solubility.

Uses

TCO-C3-PEG3-C3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

TCO-PEG3-Amine Preparation Products And Raw materials

Raw materials

Preparation Products

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TCO-PEG3-Amine Suppliers

Alfa Chemistry
Tel
+1-5166625404;
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
20405
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
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View Lastest Price from TCO-PEG3-Amine manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
(4E)-TCO-C3-PEG3-C3-amine 2028288-77-7
Price
US $0.00/mg
Min. Order
10mg
Purity
>95.00%
Supply Ability
10mg
Release date
2024-03-21