4-Bromo-3,5-dimethylisoxazole

Product Name: 4-Bromo-3,5-dimethylisoxazole
CAS No.: 10558-25-5
Chemical Name: 4-Bromo-3,5-dimethylisoxazole
Synonyms: SKL268;BUTTPARK 33\06-98;TIMTEC-BB SBB003784;4-Bromo-dimethylisoxazole;4-Bromo-3,5-dimethylisoxa...;4-BROMO-3,5-DIMETHYLISOXAZOLE;Isoxazole, 4-broMo-3,5-diMethyl-;4-Bromo-3,5-dimethylisoxazole >4-BROMO-3,5-DIMETHYLISOXAZOLE 97%;4-Bromo-3,5-dimethylisoxazole,97%
CBNumber: CB2339447
Molecular Formula: C5H6BrNO
Formula Weight: 176.01
MOL File: 10558-25-5.mol

More

Less

4-Bromo-3,5-dimethylisoxazole Property

Boiling point:: 176 °C(lit.)
Density: 1.478 g/mL at 25 °C(lit.)
refractive index: n20/D 1.486(lit.)
Flash point:: >230 °F
storage temp.: 2-8°C
pka: -2.35±0.28(Predicted)
form: clear liquid
color: Colorless to Light orange to Yellow
Sensitive: Light Sensitive
BRN: 108522
InChI: InChI=1S/C5H6BrNO/c1-3-5(6)4(2)8-7-3/h1-2H3
InChIKey: GYHZPSUAMYIFQD-UHFFFAOYSA-N
SMILES: O1C(C)=C(Br)C(C)=N1
CAS DataBase Reference: 10558-25-5(CAS DataBase Reference)

More

Less

Safety

Safety Statements: 24/25
WGK Germany: 3
Hazard Note: Keep Cold/Light Sensitive
HS Code: 29349990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 544299
Product name: 4-Bromo-3,5-dimethylisoxazole
Purity: 95%
Packaging: 1g
Price: $21.9
Updated: 2023/06/20

Sigma-Aldrich

Product number: 544299
Product name: 4-Bromo-3,5-dimethylisoxazole
Purity: 95%
Packaging: 5g
Price: $63.4
Updated: 2023/06/20

TCI Chemical

Product number: B3519
Product name: 4-Bromo-3,5-dimethylisoxazole
Purity: >98.0%(GC)
Packaging: 1g
Price: $20
Updated: 2024/03/01

TCI Chemical

Product number: B3519
Product name: 4-Bromo-3,5-dimethylisoxazole
Purity: >98.0%(GC)
Packaging: 5g
Price: $79
Updated: 2024/03/01

TRC

Product number: B691648
Product name: 4-Bromo-3,5-dimethylisoxazole
Packaging: 1g
Price: $75
Updated: 2021/12/16

More

Less

4-Bromo-3,5-dimethylisoxazole Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow liquid

Uses

4-Bromo-3,5-dimethylisoxazole may be used in the preparation of (tert-butyldimethylsilyl)-(3,5-dimethylisoxazol-4-yl)phenylamine and 3,3′,5,5′-tetramethyl-4,4′-diisoxazole.[21}

General Description

4-Bromo-3,5-dimethylisoxazole is also known as 3,5-dimethyl-4-bromoisoxazole.

Synthesis

300-87-8

10558-25-5

The general procedure for the synthesis of 4-bromo-3,5-dimethylisoxazole from 3,5-dimethylisoxazole is as follows: 1. Preparation of intermediate 105 (4-bromo-3,5-dimethyl-1,2-oxazole): DMF (53 mL) was added to a 250 mL round-bottomed flask fitted with a magnetic stirrer. 2. 3,5-dimethyl-1,2-oxazole (5.3 g, 54.57 mmol) and N-iodosuccinimide (11.659 g, 65.49 mmol) were sequentially added to the stirred DMF. 3. After completion of the addition, the reaction mixture was heated to 75°C and maintained for 3 hours. 4. Upon completion of the reaction, the mixture was diluted with ethyl acetate (100 mL). 5. The organic layer was washed sequentially with saturated NaHCO3 solution (100 mL), sodium thiosulfate solution (100 mL), water (200 mL) and brine (100 mL). 6. The organic layer was dried over anhydrous Na2SO4 and then concentrated under reduced pressure to remove the solvent to afford the target product 4-bromo-3,5-dimethyl-1,2-oxazole (6.1 g, 63.4% yield).

References

[1] Patent: WO2012/11125, 2012, A1. Location in patent: Page/Page column 148; 149
[2] Rend. Ist. lomb., 1936, vol. 69, p. 587,600

4-Bromo-3,5-dimethylisoxazole Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-Bromo-3,5-dimethylisoxazole Suppliers

Americas 1 Belgium 4 China 157 Czech Republic 1 Europe 1 France 1 Germany 4 India 23 Japan 2 Switzerland 2 The Netherlands 1 United Kingdom 16 United States 40 Global 253

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Ark Pharm, Inc.

Tel: 847-367-3680
Fax: 847-367-3681
Email: sales@arkpharminc.com
Country: United States
ProdList: 1670
Advantage: 56

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

More

Less

View Lastest Price from 4-Bromo-3,5-dimethylisoxazole manufacturers

Career Henan Chemical Co

Product: 4-Bromo-3,5-dimethylisoxazole 10558-25-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2019-05-24

10558-25-5, 4-Bromo-3,5-dimethylisoxazoleRelated Search:

Isoxazole ISOXAFLUTOLE Sulfisoxazole Chlorobromoisocyanurate Sulfamethoxazole 3,5-Dimethylisoxazole 2-Bromopropane Sulfadoxine Bromine 4-BROMO-3,5-DIPHENYLISOXAZOLE 3-BROMO-4,5-DIMETHYLISOXAZOLE 4-Bromo-3,5-dimethylisoxazole bromo-Dragonfly 4-BROMO-5-(4-BROMOPHENYL)-3-PHENYLISOXAZOLE 4-BROMO-5-(4-METHOXYPHENYL)-3-PHENYLISOXAZOLE SPECS AQ-776/42801685 4-BROMO-5-(4-FLUOROPHENYL)-3-PHENYLISOXAZOLE 4-BROMO-3-METHYLISOXAZOLE-5-CARBOXYLIC ACID

BUTTPARK 33\06-98

4-BROMO-3,5-DIMETHYLISOXAZOLE

4-BROMO-3,5-DIMETHYLISOXAZOLE 97%

Isoxazole, 4-broMo-3,5-diMethyl-

4-Bromo-3,5-dimethylisoxazole, tech.

4-Bromo-3,5-dimethylisoxazole,97%

4-Bromo-3,5-dimethylisoxa...

TIMTEC-BB SBB003784

4-Bromo-dimethylisoxazole

4-Bromo-3,5-dimethylisoxazole &gt

SKL268

10558-25-5

105558-25-5

C5H6BrNO

C5H5BrNO

Building Blocks

Isoxazoles

Halogenated Heterocycles

Heterocyclic Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Isoxazoles

IsoxazolesBuilding Blocks

Oxazole&Isoxazole

blocks

Bromides

Oxazoles