DIHYDROSAFROL
- Product Name
- DIHYDROSAFROL
- CAS No.
- 94-58-6
- Chemical Name
- DIHYDROSAFROL
- Synonyms
- NSC 33707;NSC 27867;AKOS 208-12;DIHYDROSAFROL;DIHYDROSAFROLE;Dihydroisosafrole;Safrole, dihydro-;rcrawastenumberu090;2',3'-Dihydrosafrole;2’,3’-dihydrosafrole
- CBNumber
- CB2342320
- Molecular Formula
- C10H12O2
- Formula Weight
- 164.2
- MOL File
- 94-58-6.mol
DIHYDROSAFROL Property
- Boiling point:
- 251.67°C (rough estimate)
- Density
- 1.0326 (rough estimate)
- refractive index
- 1.5320 (estimate)
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- Oil
- color
- Colourless to Brown
- Odor
- at 10.00 % in dipropylene glycol. spicy sassafrass
- Odor Type
- spicy
- LogP
- 3.587 (est)
- CAS DataBase Reference
- 94-58-6
- IARC
- 2B (Vol. 10, Sup 7) 1987
- EPA Substance Registry System
- Dihydrosafrole (94-58-6)
Safety
- HS Code
- 29329990
- Hazardous Substances Data
- 94-58-6(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H351Suspected of causing cancer
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P281Use personal protective equipment as required.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P391Collect spillage. Hazardous to the aquatic environment
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D449920
- Product name
- Dihydrosafrole
- Packaging
- 25mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- D449920
- Product name
- Dihydrosafrole
- Packaging
- 250mg
- Price
- $1455
- Updated
- 2021/12/16
- Product number
- CM155492
- Product name
- 5-Propylbenzo[d][1,3]dioxole
- Purity
- 95%
- Packaging
- 1g
- Price
- $405
- Updated
- 2021/12/16
DIHYDROSAFROL Chemical Properties,Usage,Production
Description
Dihydrosafrole is an oily liquid. Molecularweight=164.22; Boiling point=228℃; Wiswesser linenotation: T56 BO DO CHJ G3.
Chemical Properties
Light Yellow Oil
Occurrence
Has apparently not been reported to occur in nature.
Uses
Safrole derivative. Carcinogenic.
Definition
ChEBI: Dihydrosafrole is a member of benzodioxoles.
Preparation
By catalytic hydrogenation of safrole (Arctander, 1969).
Toxicity evaluation
The acute oral LD50 was reported as 2.26 g/kg (1.84-2.78 g/kg) in rats and as 4.30 g/kg in the mouse (Jenner, Hagan, Taylor, Cook & Fitzhugh, 1964). The acute dermal LD50 in rabbits was reported as > 5 g/kg (Shelanski & Moldovan, 1973). Daily dosage for 4 days with 770 mg dihydrosafrole/kg caused macroscopic liver lesions and one death in six treated rats (Taylor, Jenner & Jones, 1964).
General Description
Oily liquid.
Health Hazard
Inhalation of material may be harmful. Contact may cause burns to skin and eyes. Inhalation of Asbestos dust may have a damaging effect on the lungs. Fire may produce irritating, corrosive and/or toxic gases. Some liquids produce vapors that may cause dizziness or suffocation. Runoff from fire control may cause pollution.
Fire Hazard
Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot.
Safety Profile
Confirmed carcinogen with experimental carcinogenic data. Moderately toxic by ingestion and intraperitoneal routes. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Potential Exposure
Tumorigen,Mutagen, Primary Irritant. Workers may be exposed todihydrosafrole during its use as a chemical intermediate inthe production of piperonyl butoxide and related insecticidalsynergists; and in the production of fragrances for cosmeticproducts.
First aid
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.
storage
Color Code—Blue: Health Hazard/Poison: Store in asecure poison location. Prior to working with this chemical youshould be trained on its proper handling and storage. Store intightly closed containers in a cool, well-ventilated area awayfrom oxidizers and reducing agents. Where possible, automatically pump liquid from drums or other storage containers toprocess containers. A regulated, marked area should be established where this chemical is handled, used, or stored in compliance with OSHA Standard 1910.1045.
Shipping
The name of this material is not on the DOT listof materials for label and packaging standards. However,based on regulations, it may be classified as anEnvironmentally hazardous substances, liquid, n.o.s. It fallsin Hazard Class 9 and Packing Group III.[20,21]