Uses
ChemicalBook > CAS DataBase List > 4-AMINOPYRIDAZINE

4-AMINOPYRIDAZINE

Uses
Product Name
4-AMINOPYRIDAZINE
CAS No.
20744-39-2
Chemical Name
4-AMINOPYRIDAZINE
Synonyms
PYRIDAZIN-4-AMINE;4-Pyridazinamine;4-Aminopyridazin;4-AMINOPYRIDAZINE;PYRIDAZIN-4-YLAMINE;4-Pyridazinamine (9CI, ACI);4-aminopyridazine (MFCD00233975);4-AMinopyridazine pyridazin-4-amine;4-AMINOPYRIDAZINE ISO 9001：2015 REACH;Pyridazin-4-amine, 4-Amino-1,2-diazine
CBNumber
CB2361738
Molecular Formula
C4H5N3
Formula Weight
95.1
MOL File
20744-39-2.mol
More
Less

4-AMINOPYRIDAZINE Property

Melting point:
127-133°C
Boiling point:
326.2±15.0 °C(Predicted)
Density 
1.216±0.06 g/cm3(Predicted)
storage temp. 
-20°C
form 
solid
pka
6.38±0.10(Predicted)
color 
Light yellow to yellow
InChI
InChI=1S/C4H5N3/c5-4-1-2-6-7-3-4/h1-3H,(H2,5,6)
InChIKey
LUCGBEPEAUHERV-UHFFFAOYSA-N
SMILES
C1=NN=CC=C1N
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
WGK Germany 
3
HS Code 
2933998090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
777633
Product name
4-Aminopyridazine
Purity
97%
Packaging
500mg
Price
$50.37
Updated
2025/07/31
Sigma-Aldrich
Product number
CDS006078
Product name
4-Aminopyridazine
Purity
AldrichCPR
Packaging
50mg
Price
$68.1
Updated
2023/06/20
TRC
Product number
P991295
Product name
4-Pyridazinamine
Packaging
1g
Price
$55
Updated
2021/12/16
Matrix Scientific
Product number
069821
Product name
4-Aminopyridazine
Purity
95%
Packaging
1g
Price
$39
Updated
2021/12/16
Apolloscientific
Product number
OR60046
Product name
4-Aminopyridazine
Purity
97%
Packaging
1g
Price
$44
Updated
2021/12/16
More
Less

4-AMINOPYRIDAZINE Chemical Properties,Usage,Production

Uses

4-Pyridazinamine is used to prepare phosphodiesterase 10A inhibitors with reduced CYP1A2 inhibition. It is also used to synthesize ATP competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors.

Chemical Properties

yellow powder

Uses

4-Pyridazinamine is used to prepare phosphodiesterase 10A inhibitors with reduced CYP1A2 inhibition. It is also used to synthesize ATP competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors.

Synthesis

823-58-5

20744-39-2

General procedure for the synthesis of 4-aminopyridazine from 3,6-dichloropyridazin-4-amine: 1. 3,6-dichloropyridazin-4-amine (5.00 g, 18.2 mmol) was dissolved in tetrahydrofuran (100 ml), sodium hydroxide (8.00 g, 200 mmol) and water (32 ml) were added. 2. 10% palladium-carbon catalyst (500 mg) was added to the above mixture and the reaction was stirred for 2 days at room temperature under hydrogen atmosphere. 3. After completion of the reaction, the insoluble material was removed by filtration and the filtrate was concentrated. 4. 4. The concentrated residue was dissolved in methanol (100 ml), filtered again to remove the insoluble material, and the filtrate was concentrated to obtain the target product 4-aminopyridazine as a solid. Product characterization: 1H-NMR (DMSO-d6) δ; 2.51 (2H, br s), 6.00 (1H, br s), 7.81-7.85 (1H, m), 7.98-8.00 (1H, m).

References

[1] Patent: EP1813606, 2007, A1. Location in patent: Page/Page column 83-84
[2] Pharmaceutical Bulletin, 1956, vol. 4, p. 137,498
[3] Pharmaceutical Bulletin, 1956, vol. 4, p. 137,498

4-AMINOPYRIDAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-AMINOPYRIDAZINE Suppliers

China 163 Germany 2 India 2 The Netherlands 1 United Kingdom 3 United States 19 Global 190
Specs
Tel
--
Fax
--
Email
info@specs.net
Country
The Netherlands
ProdList
6833
Advantage
70
More
Less

View Lastest Price from 4-AMINOPYRIDAZINE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
4-Aminopyridazine 20744-39-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10000KG
Release date
2024-11-09
Shanghai Rlavie Technology Co ltd
Product
4-AMinopyridazine pyridazin-4-amine 20744-39-2
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%minHPLC
Supply Ability
50kgs/month
Release date
2021-11-13
Dideu Industries Group Limited
Product
4-AMINOPYRIDAZINE 20744-39-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-11-01

20744-39-2, 4-AMINOPYRIDAZINERelated Search:

3,6-dichloropyridazin-4-amine 2-Chloro-10-methyl-3,4-diazaphenoxazine Amezinium methylsulfate 3,4-Diaminopyridazine 4-AMINOPYRIDAZINE Azaphen hydrochloride 5-AMINO-3-CHLOROPYRIDAZINE 3-AMINO-6-PHENYLPYRIDAZINE 3,6-Pyridazinediamine(9CI) 6-Chloro-N-cyclopropylpyridazin-3-amine 6-methyl-3-aminopyridazine 3-aminopyridazine-6-carboxylic acid 3-AMINOPYRIDAZINE HYDROCHLORIDE,3-AMINOPYRIDAZINE HYDROCHLORIDE, 97+% 3-AMINOPYRIDAZINE,98.0+%(GC)(T),3-Aminopyridazine 97%,2-AMINOPYRIDAZINE,3-AMINOPYRIDAZINE 6-Chloro-N-methylpyridazin-3-amine 6-chloro-N-pentylpyridazin-3-amine 6-Chloro-N-ethylpyridazin-3-amine PYRIDAZINE-3,4-DIAMINE

  • 4-AMINOPYRIDAZINE
  • 4-Pyridazinamine
  • PYRIDAZIN-4-AMINE
  • PYRIDAZIN-4-YLAMINE
  • 4-Aminopyridazin
  • 4-aminopyridazine (MFCD00233975)
  • Pyridazin-4-amine, 4-Amino-1,2-diazine
  • 4-AMinopyridazine pyridazin-4-amine
  • 4-AMINOPYRIDAZINE ISO 9001：2015 REACH
  • 4-Pyridazinamine (9CI, ACI)
  • 20744-39-2
  • 20744-39-5
  • Amines
  • Pyrazines, Pyrimidines & Pyridazines