Ethyl 2-fluoropropionate

Product Name: Ethyl 2-fluoropropionate
CAS No.: 349-43-9
Chemical Name: Ethyl 2-fluoropropionate
Synonyms: ethyl 2-fluoropropanoate;Ethyl 2-fluoropropionate;2-fluoro-ethyl propionate;2-Fluoro-ethyl propanoate;Ethyl2-Fluoropropionate>Ethyl 2-fluoropropionate 98%;2-FLUOROPROPIONIC ACID ETHYL ESTER;2-fluoropropanoic acid ethyl ester;Propanoic acid, 2-fluoro-, ethyl ester;(127306-59-6) ethyl 2-fluoropropionate
CBNumber: CB2372864
Molecular Formula: C5H9FO2
Formula Weight: 120.12
MOL File: 349-43-9.mol

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Ethyl 2-fluoropropionate Property

Boiling point:: 125°C
Density: 0.997
refractive index: 1.3750-1.3790
Flash point:: 29°C
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: clear liquid
color: Colorless to Light yellow to Light orange
InChI: InChI=1S/C5H9FO2/c1-3-8-5(7)4(2)6/h4H,3H2,1-2H3
InChIKey: ODMITNOQNBVSQG-UHFFFAOYSA-N
SMILES: C(OCC)(=O)C(F)C
CAS DataBase Reference: 349-43-9(CAS DataBase Reference)

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Safety

Hazard Codes: F
Risk Statements: 10-36/38
Safety Statements: 16-36/37/39-3/9/49-26
RIDADR: 3272
HazardClass: FLAMMABLE
PackingGroup: III
HS Code: 29155090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: E0663
Product name: Ethyl 2-Fluoropropionate
Purity: >97.0%(GC)
Packaging: 5g
Price: $46
Updated: 2025/07/31

TCI Chemical

Product number: E0663
Product name: Ethyl 2-Fluoropropionate
Purity: >97.0%(GC)
Packaging: 25g
Price: $127
Updated: 2025/07/31

TRC

Product number: E917965
Product name: Ethyl 2-Fluoropropionate
Packaging: 100g
Price: $495
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0025969
Product name: ETHYL 2-FLUOROPROPIONATE
Purity: 95.00%
Packaging: 5G
Price: $797.32
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0025969
Product name: ETHYL 2-FLUOROPROPIONATE
Purity: 95.00%
Packaging: 25G
Price: $1176.29
Updated: 2021/12/16

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Ethyl 2-fluoropropionate Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to light yellow liquid

Uses

Ethyl 2-fluoropropionate is used as a solvent for lithium secondary batteries. Ethyl-2-fluoropropionate is also used as a reagent to synthesize a series of potent Nicotinic Acid (N429250) receptor agonists for the treatment of dyslipidemia, a health condition characterized by high triglyceride levels.

Synthesis Reference(s)

The Journal of Organic Chemistry, 55, p. 2311, 1990 DOI: 10.1021/jo00295a016

Synthesis

535-13-7

349-43-9

In a 2L four-neck flask equipped with a condenser, 1100 g of DMF, 273 g (2.0 mol) of ethyl 2-chloropropionate, 54 g of tetrabutylammonium bromide, 5.5 g of triethyl orthoformate and 255.2 g of potassium fluoride were added. The mixture was stirred and warmed to 100°C and reacted for 12 hours. After completion of the reaction, the mixture was purified by distillation to give 176.3 g of ethyl 2-fluoropropionate with 99.5% purity and 66.5% yield.

References

[1] Patent: CN105037150, 2017, B. Location in patent: Paragraph 0028; 0029

Ethyl 2-fluoropropionate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 2-fluoropropionate Suppliers

Americas 1 Canada 1 China 116 Europe 1 France 1 Germany 5 India 7 Japan 3 The Netherlands 1 United Kingdom 10 United States 35 Global 181

SHANG FLUORO

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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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View Lastest Price from Ethyl 2-fluoropropionate manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Ethyl 2-fluoropropionate 349-43-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-09

Career Henan Chemical Co

Product: Ethyl 2-fluoropropionate 349-43-9
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: as request
Release date: 2018-12-24

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2-fluoro-ethyl propionate

ethyl 2-fluoropropanoate

2-fluoropropanoic acid ethyl ester

2-FLUOROPROPIONIC ACID ETHYL ESTER

Ethyl 2-fluoropropionate

(127306-59-6) ethyl 2-fluoropropionate

Ethyl2-Fluoropropionate&gt

Propanoic acid, 2-fluoro-, ethyl ester

Ethyl 2-fluoropropionate ISO 9001：2015 REACH

2-Fluoro-ethyl propanoate

Ethyl 2-fluoropropionate 98%

349-43-9

C5H9FO2

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