3-Amino-4-iodopyridine

Product Name: 3-Amino-4-iodopyridine
CAS No.: 105752-11-2
Chemical Name: 3-Amino-4-iodopyridine
Synonyms: 4-Iodopyridin-3-amine;Zinc00334520;4-iodopyridin-3-amin;4-Iodo-3-pyridinamine;3-amine-4-iodopyridin;3-amino-4-Iodopyrdine;3-Amnio-4-iodopyridine;3-AMINO-4-IODOPYRIDINE;4-IODO-3-AMINOPYRIDINE;3-amine-4-iodopyridine
CBNumber: CB2377814
Molecular Formula: C5H5IN2
Formula Weight: 220.01
MOL File: 105752-11-2.mol

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3-Amino-4-iodopyridine Property

Melting point:: 69.2-69.5°C
Boiling point:: 327.2±27.0 °C(Predicted)
Density: 2.055
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: solid
pka: 4.79±0.18(Predicted)
Appearance: Light yellow to brown Solid
Sensitive: Air & Light Sensitive
InChI: InChI=1S/C5H5IN2/c6-4-1-2-8-3-5(4)7/h1-3H,7H2
InChIKey: ZJRSKTXMSIVNAU-UHFFFAOYSA-N
SMILES: C1=NC=CC(I)=C1N
CAS DataBase Reference: 105752-11-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 736023
Product name: 3-Amino-4-iodopyridine
Purity: 97%
Packaging: 500mg
Price: $64
Updated: 2025/07/31

TRC

Product number: A576618
Product name: 3-Amino-4-iodopyridine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 018238
Product name: 4-Iodo-pyridin-3-ylamine
Packaging: 1g
Price: $37
Updated: 2021/12/16

Apolloscientific

Product number: OR52091
Product name: 3-Amino-4-iodopyridine
Purity: 95%
Packaging: 10g
Price: $283
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0023970
Product name: 3-AMINO-4-IODOPYRIDINE
Purity: 95.00%
Packaging: 500MG
Price: $706.86
Updated: 2021/12/16

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3-Amino-4-iodopyridine Chemical Properties,Usage,Production

Uses

3-Amino-4-iodopyridine is a heterocyclic derivative and can be used as a pharmaceutical intermediate.

Definition

ChEBI: 3-amino-4-iodopyridine is an aminopyridine that is 3-aminopyridine carrying an additional iodo substituent at postion 4. It has a role as a Saccharomyces cerevisiae metabolite. It is an aminopyridine and an organoiodine compound.

Synthesis

113975-32-9

105752-11-2

General procedure for the synthesis of 3-amino-4-iodopyridine from N-(4-iodo-3-pyridinyl)-2,2-dimethylpropanamide: N-(4-iodo-3-pyridinyl)-2,2-dimethylpropanamide (20.00 g, 65.76 mmol) was placed in a 2 L round-bottomed flask, and 24% sulfuric acid aqueous solution (640 mL) was added. The mixture was carefully heated to 100 °C and kept for 4 hours. The progress of the reaction was monitored by analytical HPLC. Upon completion of the reaction, the mixture was cooled to room temperature and the pH was slowly adjusted to 7-8 with 4 N NaOH solution (~700 mL).Subsequently, saturated sodium bicarbonate solution was added and extracted with dichloromethane (3 x 500 mL). The organic phases were combined and concentrated to give 3-amino-4-iodopyridine (13.3 g, 92% yield).

References

[1] Journal of Medicinal Chemistry, 2007, vol. 50, # 26, p. 6519 - 6534
[2] Patent: WO2006/86609, 2006, A2. Location in patent: Page/Page column 154
[3] Patent: EP1595881, 2005, A1. Location in patent: Page/Page column 57
[4] Journal of Heterocyclic Chemistry, 1994, vol. 31, # 1, p. 11 - 16
[5] Tetrahedron Letters, 2004, vol. 45, # 46, p. 8569 - 8573

3-Amino-4-iodopyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Amino-4-iodopyridine Suppliers

China 183 Germany 2 India 6 Poland 1 United Kingdom 3 United States 19 Global 214

J & K SCIENTIFIC LTD.

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View Lastest Price from 3-Amino-4-iodopyridine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 4-Iodo-3-pyridinamine 105752-11-2
Price: US $1.60-6.60/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-19

Henan Aochuang Chemical Co.,Ltd.

Product: 3-Amino-4-iodopyridine 105752-11-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-29

PNP Biotech Co. Ltd

Product: 4-Iodo-3-pyridinamine 105752-11-2
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%
Supply Ability: Inquiry
Release date: 2023-07-04

105752-11-2, 3-Amino-4-iodopyridineRelated Search:

CYCLOPROPYL-(3-IODO-PYRIDIN-2-YL)-AMINE 5-AMINO-2-IODOPYRIDINE (5-IODO-PYRIDIN-2-YL)-CARBAMIC ACID TERT-BUTYL ESTER 5-FLUORO-3-IODO-PYRIDIN-2-YLAMINE (2-AMINO-5-IODO-PYRIDIN-3-YL)-METHANOL 3-IODO-PYRIDIN-2-YLAMINE,98%,3-IODO-PYRIDIN-2-YLAMINE N-(4-IODO-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE (4-IODO-PYRIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER 5-IODO-PYRIDIN-3-YLAMINE 2-AMINO-5-IODO-PYRIDINE-3-CARBALDEHYDE 3-IODO-PYRIDIN-4-YLAMINE 4-AMINO-5-IODOPYRIDINE-3-CARBOXALDEHYDE (3-IODO-PYRIDIN-4-YL)-CARBAMIC ACID TERT-BUTYL ESTER 5-BROMO-3-IODO-PYRIDIN-2-YLAMINE 5-CHLORO-3-IODO-PYRIDIN-2-YLAMINE 3-BROMO-5-IODO-PYRIDIN-4-YLAMINE 2-IODO-PYRIDIN-3-YLAMINE 5-IODO-PYRIDIN-2-YLAMINE

3-AMINO-4-IODOPYRIDINE

4-IODO-PYRIDIN-3-YLAMINE

4-IODO-3-AMINOPYRIDINE

4-Iodopyridin-3-amine

3-amine-4-iodopyridin

3-Amnio-4-iodopyridine

4-Iodo-3-pyridinylamine

3-amine-4-iodopyridine

Zinc00334520

3-Pyridinamine, 4-iodo-

4-Iodo-3-pyridinamine

3-Amino-4-iodopyridine 95%

3-Amino-4-iodopyridine ISO 9001：2015 REACH

4-iodopyridin-3-amin

3-amino-4-Iodopyrdine

105752-11-2

Pyridine

Heterocycles

pyrdine series