ChemicalBook > CAS DataBase List > U-73343

U-73343

Product Name
U-73343
CAS No.
142878-12-4
Chemical Name
U-73343
Synonyms
U-73343;U73343, U-73343, U 73343;U-73343 - CAS 142878-12-4 - Calbiochem;U-73343,Inhibitor,U73343,Phospholipase,inhibit;3-Methoxy-17-[6-(2,5-dioxopyrrolidin-1-yl)hexylamino]estra-1,3,5(10)-triene;1-[6-[((17β)-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-2,5-pyrrolidinedione;1-[6-((17BETA-3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL]-2,5-PYRROLIDINEDIONE;2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-;U-73343;1-[6-[((17Β)-3-METHOXYESTRA-1,3,5[10]-TRIEN-17-YL)AMINO]HEXYL]-2,5-PYRROLIDINEDIONE
CBNumber
CB2377935
Molecular Formula
C29H42N2O3
Formula Weight
466.66
MOL File
142878-12-4.mol
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U-73343 Property

Boiling point:
641.5±55.0 °C(Predicted)
Density 
1.15±0.1 g/cm3(Predicted)
storage temp. 
+15C to +30C
solubility 
ethanol: 0.93 mg/mL
form 
powder
pka
10.68±0.40(Predicted)
color 
white
Stability:
Stable for 1 year from date of purchase as supplied. Dried films prepared from chloroform solution are stable for at least 1 month at -20°. It is preferable to dissolve U-73343 immediately before use if at all possible. Use caution and retest potency if attempting.
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
U6881
Product name
U-73343
Packaging
1mg
Price
$167
Updated
2024/03/01
Sigma-Aldrich
Product number
662041
Product name
U-73343
Packaging
5mg
Price
$172
Updated
2024/03/01
Cayman Chemical
Product number
17339
Product name
U-73343
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
17339
Product name
U-73343
Purity
≥95%
Packaging
5mg
Price
$93
Updated
2024/03/01
Sigma-Aldrich
Product number
U6881
Product name
U-73343
Packaging
5mg
Price
$309
Updated
2024/03/01
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U-73343 Chemical Properties,Usage,Production

Description

U-73343 (142878-12-4) is a negative control for phospholipase C inhibitor U-73122 (Cat.# 10-1061).1,2 Elicits unexpected effects on rabbit parietal cells.3?Cell permeable.

Uses

U-73343 is an inactive structural analog of U-73122.

General Description

A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

Biochem/physiol Actions

Cell permeable: yes

storage

Store at RT

References

1) Bleasdale?et al. (1990),?Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils; J. Pharmacol. Exp. Ther.,?255?756 2) Morley?et al. (1992),?A new, nongenomic estrogen action: the rapid release of intracellular calcium; Endocrinology,131?1305 3) Muto?et al. (1997),?The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell; J. Pharmacol. Exp. Ther.,?282?1379

U-73343 Preparation Products And Raw materials

Raw materials

Preparation Products

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U-73343 Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel
17702719238 17702719238
Email
sales@sun-shinechem.com
Country
China
ProdList
905
Advantage
64
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Anhui kuer Bioengineering Co., Ltd
Tel
0551-65171243 13810511747
Email
kuer@kuerhuaxue.com
Country
China
ProdList
2997
Advantage
55
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20)
Fax
0539-6362799(To 20)
Country
China
ProdList
9998
Advantage
58
Shanghai BetterBioChem Co., Ltd.
Tel
+86-18017644823
Fax
- QQ:1910610264
Email
sales@betterbiochem.com
Country
China
ProdList
325
Advantage
58
Wuhan Sun-shine Bio-technology Corporation Limited
Tel
+86-027-6552-2453
Email
sales@sun-shinechem.com
Country
China
ProdList
727
Advantage
58

142878-12-4, U-73343Related Search:


  • U-73343;1-[6-[((17Β)-3-METHOXYESTRA-1,3,5[10]-TRIEN-17-YL)AMINO]HEXYL]-2,5-PYRROLIDINEDIONE
  • 1-[6-((17BETA-3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL]-2,5-PYRROLIDINEDIONE
  • U-73343
  • 1-[6-[((17β)-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-2,5-pyrrolidinedione
  • 3-Methoxy-17-[6-(2,5-dioxopyrrolidin-1-yl)hexylamino]estra-1,3,5(10)-triene
  • U73343, U-73343, U 73343
  • U-73343 - CAS 142878-12-4 - Calbiochem
  • 2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-
  • U-73343,Inhibitor,U73343,Phospholipase,inhibit
  • 142878-12-4
  • APIS