ChemicalBook > CAS DataBase List > U-73343

U-73343

Product Name
U-73343
CAS No.
142878-12-4
Chemical Name
U-73343
Synonyms
U-73343;U73343, U-73343, U 73343;U-73343 - CAS 142878-12-4 - Calbiochem;U-73343,Inhibitor,U73343,Phospholipase,inhibit;3-Methoxy-17-[6-(2,5-dioxopyrrolidin-1-yl)hexylamino]estra-1,3,5(10)-triene;1-[6-[((17β)-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-2,5-pyrrolidinedione;1-[6-((17BETA-3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL]-2,5-PYRROLIDINEDIONE;2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-;U-73343;1-[6-[((17Β)-3-METHOXYESTRA-1,3,5[10]-TRIEN-17-YL)AMINO]HEXYL]-2,5-PYRROLIDINEDIONE
CBNumber
CB2377935
Molecular Formula
C29H42N2O3
Formula Weight
466.66
MOL File
142878-12-4.mol
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U-73343 Property

Boiling point:
641.5±55.0 °C(Predicted)
Density 
1.15±0.1 g/cm3(Predicted)
storage temp. 
+15C to +30C
solubility 
ethanol: 0.93 mg/mL
form 
powder
pka
10.68±0.40(Predicted)
color 
white
Stability:
Stable for 1 year from date of purchase as supplied. Dried films prepared from chloroform solution are stable for at least 1 month at -20°. It is preferable to dissolve U-73343 immediately before use if at all possible. Use caution and retest potency if attempting.
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
U6881
Product name
U-73343
Packaging
1mg
Price
$167
Updated
2024/03/01
Sigma-Aldrich
Product number
662041
Product name
U-73343
Packaging
5mg
Price
$172
Updated
2024/03/01
Cayman Chemical
Product number
17339
Product name
U-73343
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
17339
Product name
U-73343
Purity
≥95%
Packaging
5mg
Price
$93
Updated
2024/03/01
Sigma-Aldrich
Product number
U6881
Product name
U-73343
Packaging
5mg
Price
$309
Updated
2024/03/01
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U-73343 Chemical Properties,Usage,Production

Description

U-73343 (142878-12-4) is a negative control for phospholipase C inhibitor U-73122 (Cat.# 10-1061).1,2 Elicits unexpected effects on rabbit parietal cells.3?Cell permeable.

Uses

U-73343 is an inactive structural analog of U-73122.

General Description

A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

Biochem/physiol Actions

Cell permeable: yes

storage

Store at RT

References

1) Bleasdale?et al. (1990),?Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils; J. Pharmacol. Exp. Ther.,?255?756 2) Morley?et al. (1992),?A new, nongenomic estrogen action: the rapid release of intracellular calcium; Endocrinology,131?1305 3) Muto?et al. (1997),?The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell; J. Pharmacol. Exp. Ther.,?282?1379

U-73343 Preparation Products And Raw materials

Raw materials

Preparation Products

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U-73343 Suppliers

China 53 Germany 1 Japan 2 Switzerland 3 United Kingdom 2 United States 21 Global 82
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142878-12-4, U-73343Related Search:

Citicoline sodium Phosphatidylinositol (Soy) SodiuM 2-Heptadecanone 2-(P-AMYLCINNAMOYL)AMINO-4-CHLOROBENZOIC ACID OLEYLOXYETHYL PHOSPHORYLCHOLINE BROMOENOL LACTONE Thioetheramide PC UMBELLIFERYL ARACHIDONATE LUFFARIELLOLIDE 73343, Electrolytic tough pitch copper ( O) N,N'-DI-N-BUTYL-1,6-HEXANEDIAMINE CHEMBRDG-BB 4024874 U-73343 1-Pentyl-2-Pyrrolidone N-butylcyclopentanamine 1-HEXYL-PYRROLIDIN-2-ONE N-AMYLSUCCINIMIDE N-BUTYLSUCCINIMIDE

  • U-73343;1-[6-[((17Β)-3-METHOXYESTRA-1,3,5[10]-TRIEN-17-YL)AMINO]HEXYL]-2,5-PYRROLIDINEDIONE
  • 1-[6-((17BETA-3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL]-2,5-PYRROLIDINEDIONE
  • U-73343
  • 1-[6-[((17β)-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-2,5-pyrrolidinedione
  • 3-Methoxy-17-[6-(2,5-dioxopyrrolidin-1-yl)hexylamino]estra-1,3,5(10)-triene
  • U73343, U-73343, U 73343
  • U-73343 - CAS 142878-12-4 - Calbiochem
  • 2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-
  • U-73343,Inhibitor,U73343,Phospholipase,inhibit
  • 142878-12-4
  • APIS