U-73343
- Product Name
- U-73343
- CAS No.
- 142878-12-4
- Chemical Name
- U-73343
- Synonyms
- U-73343;U73343, U-73343, U 73343;U-73343 - CAS 142878-12-4 - Calbiochem;U-73343,Inhibitor,U73343,Phospholipase,inhibit;3-Methoxy-17-[6-(2,5-dioxopyrrolidin-1-yl)hexylamino]estra-1,3,5(10)-triene;1-[6-[((17β)-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-2,5-pyrrolidinedione;1-[6-((17BETA-3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL]-2,5-PYRROLIDINEDIONE;2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-;U-73343;1-[6-[((17Β)-3-METHOXYESTRA-1,3,5[10]-TRIEN-17-YL)AMINO]HEXYL]-2,5-PYRROLIDINEDIONE
- CBNumber
- CB2377935
- Molecular Formula
- C29H42N2O3
- Formula Weight
- 466.66
- MOL File
- 142878-12-4.mol
U-73343 Property
- Boiling point:
- 641.5±55.0 °C(Predicted)
- Density
- 1.15±0.1 g/cm3(Predicted)
- storage temp.
- +15C to +30C
- solubility
- ethanol: 0.93 mg/mL
- form
- powder
- pka
- 10.68±0.40(Predicted)
- color
- white
- Stability:
- Stable for 1 year from date of purchase as supplied. Dried films prepared from chloroform solution are stable for at least 1 month at -20°. It is preferable to dissolve U-73343 immediately before use if at all possible. Use caution and retest potency if attempting.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- U6881
- Product name
- U-73343
- Packaging
- 1mg
- Price
- $167
- Updated
- 2024/03/01
- Product number
- 662041
- Product name
- U-73343
- Packaging
- 5mg
- Price
- $172
- Updated
- 2024/03/01
- Product number
- 17339
- Product name
- U-73343
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 17339
- Product name
- U-73343
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- U6881
- Product name
- U-73343
- Packaging
- 5mg
- Price
- $309
- Updated
- 2024/03/01
U-73343 Chemical Properties,Usage,Production
Description
U-73343 (142878-12-4) is a negative control for phospholipase C inhibitor U-73122 (Cat.# 10-1061).1,2 Elicits unexpected effects on rabbit parietal cells.3?Cell permeable.
Uses
U-73343 is an inactive structural analog of U-73122.
General Description
A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.
Biochem/physiol Actions
Cell permeable: yes
storage
Store at RT
References
1) Bleasdale?et al. (1990),?Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils; J. Pharmacol. Exp. Ther.,?255?756 2) Morley?et al. (1992),?A new, nongenomic estrogen action: the rapid release of intracellular calcium; Endocrinology,131?1305 3) Muto?et al. (1997),?The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell; J. Pharmacol. Exp. Ther.,?282?1379