ChemicalBook > CAS DataBase List > 2-Amino-4-methoxypyridine

2-Amino-4-methoxypyridine

Product Name
2-Amino-4-methoxypyridine
CAS No.
10201-73-7
Chemical Name
2-Amino-4-methoxypyridine
Synonyms
4-METHOXYPYRIDIN-2-AMINE;4-METHOXY-PYRIDIN-2-YLAMINE;KML-35;CML-032;4-Methoxypyridin-2-amin;4-Methoxy-2-pyridinamine;2-PyridinaMine,4-Methoxy;4-Methoxy-2-aMinopyridine;2-AMINO-4-METHOXYPYRIDINE;2-AMINO-4-METHOXYLPYRIDINE
CBNumber
CB2379186
Molecular Formula
C6H8N2O
Formula Weight
124.14
MOL File
10201-73-7.mol
More
Less

2-Amino-4-methoxypyridine Property

Melting point:
120-121°C
Boiling point:
258.6±20.0 °C(Predicted)
Density 
1.139±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO, Methanol
pka
7.79±0.11(Predicted)
form 
Solid
color 
Pale yellow
Water Solubility 
Soluble in Dimethyl sulfoxide, methanol. Slightly soluble in water.
Sensitive 
Air Sensitive
λmax
280nm(CHCl3)(lit.)
InChI
InChI=1S/C6H8N2O/c1-9-5-2-3-8-6(7)4-5/h2-4H,1H3,(H2,7,8)
InChIKey
QPHBCOSULYSASF-UHFFFAOYSA-N
SMILES
C1(N)=NC=CC(OC)=C1
CAS DataBase Reference
10201-73-7(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-36/37/38
Safety Statements 
36/37/39
WGK Germany 
3
HazardClass 
IRRITANT
HazardClass 
6.1
HS Code 
2933399990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
796956
Product name
4-Methoxypyridin-2-ylamine
Purity
95%
Packaging
1g
Price
$13.8
Updated
2022/05/15
TCI Chemical
Product number
A2690
Product name
2-Amino-4-methoxypyridine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$47
Updated
2025/07/31
TCI Chemical
Product number
A2690
Product name
2-Amino-4-methoxypyridine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$138
Updated
2025/07/31
Usbiological
Product number
002332
Product name
2-Amino-4-methoxypyridine
Packaging
5g
Price
$460
Updated
2021/12/16
TRC
Product number
A611995
Product name
2-Amino-4-methoxypyridine
Packaging
10g
Price
$210
Updated
2021/12/16
More
Less

2-Amino-4-methoxypyridine Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

2-Amino-4-methoxypyridine is a highly selective inducible nitric oxide synthase inhibitors.

Synthesis Reference(s)

The Journal of Organic Chemistry, 72, p. 4554, 2007 DOI: 10.1021/jo070189y

Synthesis

19798-80-2

124-41-4

10201-73-7

General procedure for the synthesis of 2-amino-4-methoxypyridine from 2-amino-4-chloropyridine and sodium methanol: 4-chloropyridin-2-amine (10 g, 78.1 mmol) was dissolved in sodium methanol solution (50 mL, 1 M) in a sealed reaction tube. The reaction mixture was heated at 145 °C for 6 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography using 10% dichloromethane solution in methanol as eluent to give 7.7 g (79% yield) of 2-amino-4-methoxypyridine as an off-white solid. Mass spectrometry analysis (ESI): m/z = 125.04 [M + H]+, 281.75 [M/2 + H]+. LCMS retention time: tR = 0.17 min.

References

[1] Patent: WO2015/106292, 2015, A1. Location in patent: Paragraph 00592; 00603; 00604
[2] Journal of Organometallic Chemistry, 1996, vol. 523, # 2, p. 145 - 151
[3] Australian Journal of Chemistry, 1982, vol. 35, # 9, p. 1841 - 1849
[4] Australian Journal of Chemistry, 1982, vol. 35, # 10, p. 2025 - 2034
[5] Patent: WO2012/151137, 2012, A1. Location in patent: Page/Page column 50-51

2-Amino-4-methoxypyridine Preparation Products And Raw materials

Raw materials

Sodium 2-Amino-4-chloropyridine Methanol

Preparation Products

More
Less

2-Amino-4-methoxypyridine Suppliers

Americas 1 Canada 2 China 267 Europe 1 France 1 Germany 4 India 12 Japan 1 Switzerland 1 United Kingdom 7 United States 26 Global 323
Beijing Jianuode Pharmaceutical Technology Co., Ltd.
Tel
010-67267894 18611880885
Email
gianord@163.com
Country
China
ProdList
31
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5000
Advantage
55
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
ChemFuture PharmaTech (Jiangsu) Ltd
Tel
5108538618
Fax
86 510 85386988-8017
Email
suger.wang@chemfuture.com
Country
China
ProdList
832
Advantage
65
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Suzhou Ryan Pharmaceutical Technology Co., Ltd.
Tel
0512-68780025 18962125825
Email
sales@ryanchem.com
Country
China
ProdList
167
Advantage
62
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4000
Advantage
55
Shanghai Hope Chem Co., Ltd.，
Tel
+21-18501659228 18501659228
Fax
sales@hope-chem.com
Email
info@hope-chem.com
Country
China
ProdList
474
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
Shanghai Famo Bio-chemical Technology Company Ltd.
Tel
021-02136680027 15800370750
Email
1706640024@qq.com
Country
China
ProdList
570
Advantage
56
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Wuhan Kaymke Chemical Co., Ltd.,
Tel
027-027-87342388 18086026008
Fax
027-87342388
Email
sales@kaymke.com
Country
China
ProdList
3731
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4566
Advantage
55
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2864
Advantage
52
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Hebei Summedchem Co.,Ltd
Tel
0319-5801333-8008 15630992918
Email
sales@summedchem.com
Country
China
ProdList
965
Advantage
58
Chimica Laboratories Co., Ltd
Tel
0086-573-82585213
Fax
0086-573-82585233
Email
bai@chimicalabs.com
Country
China
ProdList
861
Advantage
64
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Nanjing Credit Trading Co.,Ltd
Tel
025-52164950
Fax
025-86800069
Email
Googlexu_0114@sina.com
Country
China
ProdList
644
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Country
China
ProdList
2930
Advantage
58
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9476
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10263
Advantage
55
Shanghai Xingui Biotechnology Co., Ltd.
Tel
15121041756
Email
xingui2022@126.com
Country
China
ProdList
9979
Advantage
58
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Chengdu BoShi Technology Co., Ltd.
Tel
13982188065
Fax
-
Email
2983871989@qq.com
Country
China
ProdList
49
Advantage
55
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
More
Less

View Lastest Price from 2-Amino-4-methoxypyridine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Amino-4-methoxypyridine 10201-73-7
Price
US $10.00-8.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-12-06
R&D Scientific Inc.
Product
2-Amino-4-methoxy pyridine 10201-73-7
Price
US $980.00/g
Min. Order
1g
Purity
98
Supply Ability
500 Kg
Release date
2024-03-27
Hebei Fengqiang Trading Co., LTD
Product
2-Amino-4-methoxypyridine 10201-73-7
Price
US $100.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2023-06-13

10201-73-7, 2-Amino-4-methoxypyridineRelated Search:

4-Dimethylaminopyridine 6-Aminocaproic acid Glycine ALTRENOGEST 3-Amino-4-methylpyridine 3-Aminopyridine N-Ethylmethylamine Triethanolamine 2-Aminopyridine Triethylamine 4-Methoxypyridine 2,6-Diaminopyridine Bis(2-ethylhexyl)amine Dibenzylamine 4-Methylpyridin-2-amine 2-Aminophenol Tris(hydroxymethyl)aminomethane 4-Aminopyridine

  • 2-AMINO-4-METHOXYPYRIDINE
  • 4-METHOXYPYRIDIN-2-AMINE
  • 4-METHOXY-PYRIDIN-2-YLAMINE
  • 4-Methoxy-Pyridine-2-ylamine
  • 2-AMINO-4-METHOXYLPYRIDINE
  • 4-METHOXY-PYRIDIN-2-YLAMINE, 98.5%
  • 4-Methoxy-2-aMinopyridine
  • 4-(Methyloxy)-2-pyridinaMine
  • 2-PyridinaMine,4-Methoxy
  • 2-AMino-4-Methoxypyridine, 97+%
  • 4-Methoxy-2-pyridinamine
  • CML-032
  • 4-Methoxypyridin-2-amin
  • 4-Methoxypyridin-2-ylamine 95%
  • 2-Amino-4-methoxypyridine &gt
  • 2-Amino-4-methoxypyridine ISO 9001：2015 REACH
  • KML-35
  • N,N'-thiocarbonyldiimidazole
  • 10201-73-7
  • 10201-73-1
  • Heterocycle-Pyridine series
  • Pyridine
  • pharmacetical
  • Amines
  • Pyridines
  • Amines and Anilines
  • Heterocycles
  • intermediate