PHENAMIL

Product Name: PHENAMIL
CAS No.: 2038-35-9
Chemical Name: PHENAMIL
Synonyms: PHENAMIL;phenylamil;phenamil methanesulfonate salt;Phenamil methanesulfonate (free base);3,5-diamino-N-[amino(anilino)methylene]-6-chloro-pyrazinamide;3,5-DIAMINO-6-CHLORO-N-[IMINO(PHENYLAMINO)METHYL]-PYRAZINECAR-BOXAMIDE;3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine-2-carboxamide;3,5-diamino-N-[amino(anilino)methylidene]-6-chloropyrazine-2-carboxamide;2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-;3,5-bis(azanyl)-N-[azanyl-(phenylamino)methylidene]-6-chloro-pyrazine-2-carboxamide
CBNumber: CB2384179
Molecular Formula: C12H12ClN7O
Formula Weight: 305.72
MOL File: 2038-35-9.mol

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PHENAMIL Property

Melting point:: >181°C (dec.)
Density: 1.65±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: >15 mg/mL
form: solid
pka: 8.10±0.46(Predicted)
color: yellow

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 3379
Product name: Phenamil
Purity: ≥99%(HPLC)
Packaging: 50
Price: $353
Updated: 2021/12/16

Usbiological

Product number: 145690
Product name: Phenamil
Packaging: 10mg
Price: $325
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008629
Product name: PHENAMIL
Purity: 95.00%
Packaging: 5MG
Price: $254.1
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008629
Product name: PHENAMIL
Purity: 95.00%
Packaging: 25MG
Price: $863.48
Updated: 2021/12/16

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PHENAMIL Chemical Properties,Usage,Production

Uses

Phenamil Methanesulfonate Salt induced differentiation and peroxisome proliferator-activator receptor γ expression through ETS variant 4 in mouse preadipocyte

Definition

ChEBI: Phenylamil is a member of pyrazines and a member of guanidines.

Enzyme inhibitor

This amiloride derivative (FW = 306.73 g/mol; CAS 2038-35-9), also known as 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine carboxamide, irreversibly inhibits amiloride-sensitive Na+ channels. It is often supplied commercially as the methanesulfonate salt. Na+ channel blockers, such as phenamil and benzamil, are be alsoing explored as a way to counteract the hyperabsorption of NaCl in cystic fibrosis airways. Target(s): diamine oxidase; Na+ channels; and Na+ -driven flagellar motility.

PHENAMIL Preparation Products And Raw materials

Raw materials

Preparation Products

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PHENAMIL Suppliers

China 22 Switzerland 1 United Kingdom 2 United States 6 Global 31

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Jinan Yaoyan Pharmaceutical Co., Ltd.

Tel
Fax: -
Email: jnyaoyan@163.com
Country: China
ProdList: 3069
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57423
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

Jingmo (Xiamen) Biotechnology Co., Ltd

Tel: 13621943973; 13621943973
Email: sales@jamxmpharmatech.com
Country: China
ProdList: 1111
Advantage: 58

Changzhou Furuisi Biotechnology Co., Ltd

Tel: 0519-85524369
Email: 3477467573@qq.com
Country: China
ProdList: 8617
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19885
Advantage: 58

2038-35-9, PHENAMILRelated Search:

phenamil receptor PHENAMIL METHANESULFONATE 5-AMINOPYRAZINE-2-CARBOXAMIDE PHENAMIL 6-CHLORO-2-PYRAZINECARBOXAMIDE 2-pyrazinoylguanidine 2-amino-3-chloro-5-methyl-pyrazine 6-CHLORO-3,5-DIAMINO-2-PYRAZINECARBOXAMIDE 2,6-Pyrazinediamine(9CI) 3-AMINO-6-CHLOROPYRAZINE-2-CARBALDEHYDE PHENAMIL METHANESULFONATE 5-(N,N-HEXAMETHYLENE)-AMILORIDE 2-Amino-5-chloropyrazine (PYRAZIN-2-YL)METHANAMINEHYDROCHLORIDE 3-AMINO-N-METHYLPYRAZINE-2-CARBOXAMIDE 2-Chloro-6-methylpyrazine

PHENAMIL

3,5-DIAMINO-6-CHLORO-N-[IMINO(PHENYLAMINO)METHYL]-PYRAZINECAR-BOXAMIDE

3,5-diamino-6-chloro-n-[imino(phenylamino)methyl]pyrazinecarboxamide methanesulfonate salt

phenamil methanesulfonate salt

phenylamil

3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine-2-carboxamide

3,5-bis(azanyl)-N-[azanyl-(phenylamino)methylidene]-6-chloro-pyrazine-2-carboxamide

3,5-diamino-N-[amino(anilino)methylene]-6-chloro-pyrazinamide

3,5-diamino-N-[amino(anilino)methylidene]-6-chloropyrazine-2-carboxamide

Phenamil methanesulfonate (free base)

2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-

2038-35-9

C12H12ClN7OCH3SO3H

C12H12ClN7O

Irreversible inhibitor of amiloride-sensitive Na+ channels; derivative of amiloride.

Cell Biology

Cell Signaling and Neuroscience

BioChemical

Amiloride and Derivatives

Monovalent Ion Channels

Ion Channels

Sodium Channel Modulators

Voltage-gated Ion Channels