Febuprol
- Product Name
- Febuprol
- CAS No.
- 3102-00-9
- Chemical Name
- Febuprol
- Synonyms
- h-33;valbil;k-10033;FEBUPROL;Valbilan;NSC 30151;Febuprol USP/EP/BP;1-butoxy-3-phenoxy-2-propano;1-butoxy-3-phenoxy-2-propanol;2-Propanol, 1-butoxy-3-phenoxy-
- CBNumber
- CB2400277
- Molecular Formula
- C13H20O3
- Formula Weight
- 224.3
- MOL File
- 3102-00-9.mol
Febuprol Property
- Melting point:
- 25°C
- Boiling point:
- bp11 165°; bp1.0 125-132°
- Density
- d420 1.027
- refractive index
- nD20 1.5004
- storage temp.
- 2-8°C
- CAS DataBase Reference
- 3102-00-9(CAS DataBase Reference)
Safety
- Toxicity
- LD50 in mice, rats (mg/kg): 3050, 2370 orally; 436, 400 i.p. (Hofrichter)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- API0004560
- Product name
- FEBUPROL
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $630
- Updated
- 2021/12/16
- Product number
- API0004560
- Product name
- FEBUPROL
- Purity
- 95.00%
- Packaging
- 100G
- Price
- $2449.76
- Updated
- 2021/12/16
- Product number
- CM131810
- Product name
- 1-butoxy-3-phenoxypropan-2-ol
- Purity
- 95%
- Packaging
- 1g
- Price
- $296
- Updated
- 2021/12/16
- Product number
- CD12085029
- Product name
- 1-Butoxy-3-phenoxypropan-2-ol
- Purity
- 95%
- Packaging
- 1g
- Price
- $313
- Updated
- 2021/12/16
- Product number
- 3102009
- Product name
- 1-Butoxy-3-phenoxypropan-2-ol
- Packaging
- 1g
- Price
- $400
- Updated
- 2021/12/16
Febuprol Chemical Properties,Usage,Production
Originator
Valbil,Rohm Pharma,W. Germany,1981
Definition
ChEBI: Febuprol is an aromatic ether.
Manufacturing Process
Initially, 4.5 g (0.08 mol) pulverized potassium hydroxide was dissolved in
300 ml isopropanol in a 500 ml four-neck flask equipped with stirrer, intensive
cooler, dropping funnel and feed pipe for the gas treatment with nitrogen.
Then, 52.0 g (0.4 mol) n-butylglycidyl ether and 41.4 g (0.44 mol) phenol
was added thereto, whereafter the material was heated to boiling under
nitrogen. The material was stirred, about 8.5 hours, until no glycidyl ether
could be determined, e.g., by gas chromatography.
After the suspension was cooled under nitrogen, the solvent was distilled off
under vacuum. The residue was taken up in 200 ml water and the milky
emulsion extracted exhaustively with ether. From the organic phase, the
excess butylglycidyl ether was extracted with diluted potassium hydroxide
solution. The ether phase was washed neutral with water and the solvent
removed after drying with sodium sulfate. The remaining oily residue was
distilled under vacuum; there was obtained a colorless liquid of BP
123.5°C/0.07 mm. Yield: 81.8 g (91.1% of the theory)
Therapeutic Function
Choleretic
Febuprol Preparation Products And Raw materials
Raw materials
Preparation Products
Febuprol Suppliers
View Lastest Price from Febuprol manufacturers
- Product
- Febuprol 3102-00-9
- Price
- US $1.00/KG
- Min. Order
- 1G
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-08-20