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(TRIMETHYLSILYL)ACETONITRILE

Product Name
(TRIMETHYLSILYL)ACETONITRILE
CAS No.
18293-53-3
Chemical Name
(TRIMETHYLSILYL)ACETONITRILE
Synonyms
TMSAN;2-(Trimethy;Einecs 242-169-5;TRIMETHYLSILYACETONITRILE;(TRIMETHYLSILYL)ACETONITRILE;2-Trimethylsilylacetonitrile;(CYANOMETHYL)TRIMETHYLSILANE;trimethylsilanyl-acetonitrile;2-(Trimethylsilyl)acetonitrile;Acetonitrile, (trimethylsilyl)-
CBNumber
CB2403137
Molecular Formula
C5H11NSi
Formula Weight
113.23
MOL File
18293-53-3.mol
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(TRIMETHYLSILYL)ACETONITRILE Property

Boiling point:
65-70 °C20 mm Hg(lit.)
Density 
0.827 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.420(lit.)
Flash point:
122 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Sol most common organic solvents.
form 
Liquid
color 
Clear colorless to straw
Specific Gravity
0.829
Hydrolytic Sensitivity
4: no reaction with water under neutral conditions
BRN 
1738845
InChIKey
WJKMUGYQMMXILX-UHFFFAOYSA-N
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Safety

Hazard Codes 
T
Risk Statements 
10-23/24/25-36/37/38
Safety Statements 
26-36/37/39-45
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
21
TSCA 
No
HazardClass 
3.2
PackingGroup 
III
HS Code 
29310099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P311Call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

AK Scientific
Product number
3119BA
Product name
(Trimethylsilyl)acetonitrile
Packaging
10g
Price
$546
Updated
2021/12/16
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(TRIMETHYLSILYL)ACETONITRILE Chemical Properties,Usage,Production

Physical properties

bp 84–85 °C/54 mmHg, 66 °C/35 mmHg, 65–70 °C/20 mmHg;3 d 0.827 g cm?3.

Uses

α-carbanion is a useful alternative to LiCH2CN for nucleophilic cyanomethylation; (Z)-selective Peterson alkenation). Trimethylsilylacetonitrile participates in the following synthesis reactions: Metalation, Peterson Alkenation (Cyanomethylenation), Michael Addition, Reactions with Other Electrophiles, Cyanomethylation, Metal-Catalyzed Reactions etc.

Uses

(Trimethylsilyl)acetonitrile has been used in catalytic cyanomethylation of various carbonyl compounds in the presence of Lewis bases.

Preparation

From chlorotrimethylsilane, zinc, and XCH2CN, (X = Cl, 61% yield; X = Br, 81% yield).

Purification Methods

Check if NMR and IR spectra show impurities; if present dissolve it in *C6H6 (10volumes), wash it with buffer (AcOH/AcONa pH ca 7) several times, dry (CaCl2) it, evaporate and distil it. IR: (CCl4) 2215 (CN) cm-1, NMR (CCl4): 0.23 (s, 9H, SiMe3), and 1.53 (s, 2H, CH2CN). [Matsuda et al. J Chem Soc, Perkin Trans 1 26 1979, Beilstein 4 IV 3974.]

(TRIMETHYLSILYL)ACETONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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(TRIMETHYLSILYL)ACETONITRILE Suppliers

Anyang Hongmeng New Materials Co., Ltd
Tel
19588588067 19588588067
Email
19588588067@163.com
Country
China
ProdList
9761
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
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61
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19179
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
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57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
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View Lastest Price from (TRIMETHYLSILYL)ACETONITRILE manufacturers

Hebei Kingfiner Technology Development Co.Ltd
Product
(TRIMETHYLSILYL)ACETONITRILE 18293-53-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500000kg
Release date
2023-11-17
Zhuozhou Wenxi import and Export Co., Ltd
Product
(Trimethylsilyl)acetonitrile 99% 18293-53-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

18293-53-3, (TRIMETHYLSILYL)ACETONITRILERelated Search:


  • TMSAN
  • (TRIMETHYLSILYL)ACETONITRILE
  • trimethylsilanyl-acetonitrile
  • (Trimethylsilyl)acetonitrile,(Cyanomethyl)trimethylsilane, TMSAN
  • 2-(Trimethylsilyl)acetonitrile
  • 2-Trimethylsilylacetonitrile
  • Einecs 242-169-5
  • Acetonitrile, 2-(triMethylsilyl)-
  • (TriMethylsilyl)acetonitrile 99%
  • 2-(Trimethy
  • (CYANOMETHYL)TRIMETHYLSILANE
  • Acetonitrile, (trimethylsilyl)-
  • TRIMETHYLSILYACETONITRILE
  • (Cyanomethyl)trimethylsilane, TMSAN
  • 18293-53-3
  • CH33SiCH2CN
  • Building Blocks
  • C1 to C5
  • Nitrogen Compounds
  • Organic Building Blocks
  • Cyanides/Nitriles