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C8 CERAMIDE

Product Name
C8 CERAMIDE
CAS No.
74713-59-0
Chemical Name
C8 CERAMIDE
Synonyms
C8 CERAMIDE;CERAMIDE C8;08:0 CERAMIDE;N-Octanoyl-D-erythr;N-OCTANOYLSPHINGOSINE;C8-D-ERYTHRO-CERAMIDE;C8 CERAMINE, D-ERYTHRO;N-Octanoyl-D-erythro-sp;C8 Ceramide (d18:1/8:0);N-OCTANOYL-D-SPHINGOSINE
CBNumber
CB2432038
Molecular Formula
C26H51NO3
Formula Weight
425.69
MOL File
74713-59-0.mol
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C8 CERAMIDE Property

Melting point:
68-70°C
Boiling point:
541.37°C (rough estimate)
Density 
0.9974 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
−20°C
solubility 
DMSO or ethanol: soluble
form 
waxy solid
color 
White
Stability:
Temperature Sensitive
CAS DataBase Reference
74713-59-0(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29225000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J67190
Product name
C8 Ceramide, 98%
Packaging
5mg
Price
$89.7
Updated
2021/12/16
Alfa Aesar
Product number
J67190
Product name
C8 Ceramide, 98%
Packaging
25mg
Price
$333
Updated
2021/12/16
Cayman Chemical
Product number
62540
Product name
C-8 Ceramide
Purity
≥98%
Packaging
1mg
Price
$20
Updated
2024/03/01
Cayman Chemical
Product number
62540
Product name
C-8 Ceramide
Purity
≥98%
Packaging
5mg
Price
$69
Updated
2024/03/01
Cayman Chemical
Product number
62540
Product name
C-8 Ceramide
Purity
≥98%
Packaging
10mg
Price
$127
Updated
2024/03/01
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C8 CERAMIDE Chemical Properties,Usage,Production

Description

C8-ceramide (74713-59-0) is a cell permeable ceramide analog. Stimulates ceramide-activated protein kinase.1?Induces apoptosis.2?Reported to inhibit apoptosis and gap junction intercellular communication (GJIC) in rat liver epithelial cells.3?C8-ceramide induces the secretion of brain-derived neurotrophic factor (BDNF) from microglia?in vitro.4

Chemical Properties

Off White Powder

Uses

A biologically active, cell permeable, but nonphysiologic ceramide analog. It induces phosphorylation on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase. It stimulates IL-2 secretion and induces apoptosis

Uses

C-8 Ceramide is a ceramide analog.

Definition

ChEBI: N-octanoylsphingosine is an N-acylsphingosine in which the ceramide N-acyl group is specified as octanoyl. It is functionally related to an octanoic acid.

References

1) Mathias?et al. (1991) Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha; Proc. Natl. Acad. Sci. USA,?88?109 2) Jarvis?et al. (1993)?Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway; Proc. Natl. Acad. Sci. USA?91?73 3) Upham?et al. (2003),?Differential roles of 2,6 and 8 carbon ceramides on the modulation of gap junctional communication and apoptosis during carcinogenesis; Cancer Lett.,?191?27 4) Nakajima?et al. (2002),?Ceramide activates microglia to enhance the production/secretion of brain-derived neurotrophic factor (BDNF) without induction of deleterious factors in vitro; J. Neurochem.,?80?697

C8 CERAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from C8 CERAMIDE manufacturers

Career Henan Chemical Co
Product
C8 CERAMIDE 74713-59-0
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-20

74713-59-0, C8 CERAMIDERelated Search:


  • N-OCTANOYLSPHINGOSINE, D-ERYTHRO
  • N-OCTANOYL-D-ERYTHRO-SPHINGOSINE
  • N-OCTANOYL-D-SPHINGOSINE
  • N-OCTANOYLSPHINGOSINE
  • D-erythro-N-Octanoylsphingosine
  • N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]Octanamide
  • N-Octanoyl-C18-sphingosine
  • N-Octanoyl-D-erythr
  • Octanamide, N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-, [R-[R*,S*-(E)]]-
  • 08:0 CERAMIDE
  • C8 CERAMIDE
  • C8 CERAMINE, D-ERYTHRO
  • C8-D-ERYTHRO-CERAMIDE
  • D-ERYTHRO-SPHINGOSINE, N-OCTANOYL-
  • CERAMIDE C8
  • N-OCTANOYL-D-ERYTHRO-SPHINGOSINE, 99+%, SYNTHETICAL
  • N-Octanoyl-D-erythro-sphingosine, synthetical
  • N-Octanoyl-D-erythro-sphingosineCeramide C8
  • N-Octanoyl-D-erythro-sphingosine, synthetical, 99+%
  • [R-[R*,S*-(E)]]-N-[2-Hydroxy-1-(hydroxyMethyl)-3-heptadecenyl]octanaMide
  • N-Octanoyl-D-erythro-sp
  • D-erythro N-Octanoyl-D-erythro-sphingosine
  • N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-Octanamide
  • C8 Ceramide (d18:1/8:0)
  • N-OCTANOYL-D-ERYTHRO-SPHINGOSINE;C8 CERAMIDE (D18:1/8:0)
  • N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)heptanamide
  • Octanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-
  • 74713-59-0
  • C26H51NO3
  • Biochemicals and Reagents
  • BioChemical
  • Ceramides
  • Lipids
  • N-acylsphingosines (ceramides)
  • Sphingolipids
  • Mixed Fatty Acids
  • Activators
  • Fatty Acid Derivatives & Lipids
  • Glycerols
  • Inhibitors
  • Protein Kinase Inhibitors and Activators