C8 CERAMIDE

Product Name: C8 CERAMIDE
CAS No.: 74713-59-0
Chemical Name: C8 CERAMIDE
Synonyms: C8 CERAMIDE;CERAMIDE C8;08:0 CERAMIDE;N-Octanoyl-D-erythr;N-OCTANOYLSPHINGOSINE;C8-D-ERYTHRO-CERAMIDE;C8 CERAMINE, D-ERYTHRO;N-Octanoyl-D-erythro-sp;C8 Ceramide (d18:1/8:0);N-OCTANOYL-D-SPHINGOSINE
CBNumber: CB2432038
Molecular Formula: C26H51NO3
Formula Weight: 425.69
MOL File: 74713-59-0.mol

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C8 CERAMIDE Property

Melting point:: 68-70°C
Boiling point:: 541.37°C (rough estimate)
Density: 0.9974 (rough estimate)
refractive index: 1.6000 (estimate)
storage temp.: −20°C
solubility: DMSO or ethanol: soluble
form: waxy solid
color: White
Stability:: Temperature Sensitive
CAS DataBase Reference: 74713-59-0(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29225000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Alfa Aesar

Product number: J67190
Product name: C8 Ceramide, 98%
Packaging: 5mg
Price: $89.7
Updated: 2021/12/16

Alfa Aesar

Product number: J67190
Product name: C8 Ceramide, 98%
Packaging: 25mg
Price: $333
Updated: 2021/12/16

Cayman Chemical

Product number: 62540
Product name: C-8 Ceramide
Purity: ≥98%
Packaging: 1mg
Price: $20
Updated: 2024/03/01

Cayman Chemical

Product number: 62540
Product name: C-8 Ceramide
Purity: ≥98%
Packaging: 5mg
Price: $69
Updated: 2024/03/01

Cayman Chemical

Product number: 62540
Product name: C-8 Ceramide
Purity: ≥98%
Packaging: 10mg
Price: $127
Updated: 2024/03/01

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C8 CERAMIDE Chemical Properties,Usage,Production

Description

C8-ceramide (74713-59-0) is a cell permeable ceramide analog. Stimulates ceramide-activated protein kinase.1?Induces apoptosis.2?Reported to inhibit apoptosis and gap junction intercellular communication (GJIC) in rat liver epithelial cells.3?C8-ceramide induces the secretion of brain-derived neurotrophic factor (BDNF) from microglia?in vitro.4

Chemical Properties

Off White Powder

Uses

A biologically active, cell permeable, but nonphysiologic ceramide analog. It induces phosphorylation on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase. It stimulates IL-2 secretion and induces apoptosis

Uses

C-8 Ceramide is a ceramide analog.

Definition

ChEBI: N-octanoylsphingosine is an N-acylsphingosine in which the ceramide N-acyl group is specified as octanoyl. It is functionally related to an octanoic acid.

References

1) Mathias?et al. (1991) Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha; Proc. Natl. Acad. Sci. USA,?88?109 2) Jarvis?et al. (1993)?Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway; Proc. Natl. Acad. Sci. USA?91?73 3) Upham?et al. (2003),?Differential roles of 2,6 and 8 carbon ceramides on the modulation of gap junctional communication and apoptosis during carcinogenesis; Cancer Lett.,?191?27 4) Nakajima?et al. (2002),?Ceramide activates microglia to enhance the production/secretion of brain-derived neurotrophic factor (BDNF) without induction of deleterious factors in vitro; J. Neurochem.,?80?697

C8 CERAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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C8 CERAMIDE Suppliers

Belgium 1 Canada 1 China 86 Germany 1 India 1 Japan 2 Switzerland 2 United Kingdom 5 United States 20 Global 119

SIGMA-RBI

Tel: --
Fax: --
Country: Switzerland
ProdList: 6896
Advantage: 91

Alexis Corporation

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Email: alexis-ch@alexis-corp.ch
Country: Switzerland
ProdList: 3599
Advantage: 74

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View Lastest Price from C8 CERAMIDE manufacturers

Career Henan Chemical Co

Product: C8 CERAMIDE 74713-59-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-20

74713-59-0, C8 CERAMIDERelated Search:

N-DECANOYL-D-ERYTHRO-SPHINGOSINE N-LAUROYL-D-ERYTHRO-SPHINGOSINE N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-CERAMIDE C12 NBD-SPHINGOMYELIN C20 CERAMIDE LIGNOCERIC CERAMIDE C8 CERAMIDE C18-CEREBROSIDE GANGLIOTETRAOSYL CERAMIDE DISIALOGANGLIOSIDE GD1B 2NA LACTOSYL CERAMIDE, BOVINE,LACTOSYL CERAMIDE, PORCINE,LACTOSYL CERAMIDE,GAL-BETA1,4GLC-CERAMIDE, PORCINE,GAL-BETA1,4GLC-CERAMIDE LYSO-LACTOSYL CERAMIDE LIGNOCERIC CERAMIDE LYSO-CERAMIDE TRIHEXOSIDE GANGLIOTRIOSYL CERAMIDE GAL-BETA,3GALNAC-BETA1,4(NEU5AC-ALPHA2,3)GAL-BETA1,4GLC-BETA1,1 CERAMIDE, NH,GAL-GALNAC-GAL(SA)-GLC-CERAMIDE GAL(SA)-GALNAC-GAL(SA)-GLC-CERAMIDE D-ERYTHRO-SPHINGOSINE

N-OCTANOYLSPHINGOSINE, D-ERYTHRO

N-OCTANOYL-D-ERYTHRO-SPHINGOSINE

N-OCTANOYL-D-SPHINGOSINE

N-OCTANOYLSPHINGOSINE

D-erythro-N-Octanoylsphingosine

N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]Octanamide

N-Octanoyl-C18-sphingosine

N-Octanoyl-D-erythr

Octanamide, N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-, [R-[R*,S*-(E)]]-

08:0 CERAMIDE

C8 CERAMIDE

C8 CERAMINE, D-ERYTHRO

C8-D-ERYTHRO-CERAMIDE

D-ERYTHRO-SPHINGOSINE, N-OCTANOYL-

CERAMIDE C8

N-OCTANOYL-D-ERYTHRO-SPHINGOSINE, 99+%, SYNTHETICAL

N-Octanoyl-D-erythro-sphingosine, synthetical

N-Octanoyl-D-erythro-sphingosineCeramide C8

N-Octanoyl-D-erythro-sphingosine, synthetical, 99+%

[R-[R*,S*-(E)]]-N-[2-Hydroxy-1-(hydroxyMethyl)-3-heptadecenyl]octanaMide

N-Octanoyl-D-erythro-sp

D-erythro N-Octanoyl-D-erythro-sphingosine

N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-Octanamide

C8 Ceramide (d18:1/8:0)

N-OCTANOYL-D-ERYTHRO-SPHINGOSINE;C8 CERAMIDE (D18:1/8:0)

N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)heptanamide

Octanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-

74713-59-0

C26H51NO3

Biochemicals and Reagents

BioChemical

Ceramides

Lipids

N-acylsphingosines (ceramides)

Sphingolipids

Mixed Fatty Acids

Activators

Fatty Acid Derivatives & Lipids

Glycerols

Inhibitors

Protein Kinase Inhibitors and Activators