ChemicalBook > CAS DataBase List > Hexamethyldisiloxane

Hexamethyldisiloxane

Product Name
Hexamethyldisiloxane
CAS No.
107-46-0
Chemical Name
Hexamethyldisiloxane
Synonyms
HMDSO;HMDO;DISILOXANE;1,1,1,3,3,3-Hexamethyldisiloxane;SILICONE FLUID;Fluka AG;Hexamethylene disiloxane;hexamethyldisiloxane(hmdo);os10;HX 18
CBNumber
CB2446352
Molecular Formula
C6H18OSi2
Formula Weight
162.38
MOL File
107-46-0.mol
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Hexamethyldisiloxane Property

Melting point:
−59 °C(lit.)
Boiling point:
101 °C(lit.)
Density 
0.764 g/mL at 20 °C(lit.)
vapor density 
>1 (vs air)
vapor pressure 
20 hPa (20 °C)
refractive index 
n20/D 1.377(lit.)
Flash point:
33 °F
storage temp. 
Store below +30°C.
solubility 
0.00037g/l insoluble
form 
liquid
color 
Colorless to Almost colorless
Specific Gravity
0.76
explosive limit
0.5-21.8%(V)
Water Solubility 
insoluble
Hydrolytic Sensitivity
1: no significant reaction with aqueous systems
BRN 
1736258
Dielectric constant
2.2（20℃）
Stability:
Stable, but moisture sensitive. Highly flammable. Incompatible with strong acids, strong bases, oxidizing agents.
InChIKey
UQEAIHBTYFGYIE-UHFFFAOYSA-N
LogP
5.06 at 20℃
CAS DataBase Reference
107-46-0(CAS DataBase Reference)
NIST Chemistry Reference
Disiloxane, hexamethyl-(107-46-0)
EPA Substance Registry System
Hexamethyldisiloxane (107-46-0)
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Safety

Hazard Codes 
F,N,T
Risk Statements 
11-50/53-65-51/53-48/23/24/25-36/38-46-45
Safety Statements 
16-61-62-45-26-53
RIDADR 
UN 1993 3/PG 2
WGK Germany 
3
RTECS 
JM9237000
F 
10
Autoignition Temperature
340 °C
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29310095
Hazardous Substances Data
107-46-0(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: > 12160 mg/kg LD50 dermal Rat > 2000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.14051
Product name
Hexamethyldisiloxane
Purity
for synthesis
Packaging
100mL
Price
$43
Updated
2024/03/01
Sigma-Aldrich
Product number
8.14051
Product name
Hexamethyldisiloxane
Purity
for synthesis
Packaging
500mL
Price
$166
Updated
2024/03/01
TCI Chemical
Product number
H0091
Product name
Hexamethyldisiloxane
Purity
>98.0%(GC)
Packaging
25mL
Price
$17
Updated
2024/03/01
TCI Chemical
Product number
H0091
Product name
Hexamethyldisiloxane
Purity
>98.0%(GC)
Packaging
100mL
Price
$20
Updated
2024/03/01
Alfa Aesar
Product number
A11848
Product name
Hexamethyldisiloxane, 98+%
Packaging
100ml
Price
$25.65
Updated
2024/03/01
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Hexamethyldisiloxane Chemical Properties,Usage,Production

Chemical Properties

Hexamethyldisiloxane(HMDS) has a very low water solubility and is highly volatile. It is therefore difficult to perform biodegradability and toxicity tests. Experimental data on degradation in water are not available. Based on chemical structure, no aerobic biodegradation of HMDS in water is expected. The half-life of HMDS in marine water is thus expected to be more than 60 days and the persistence (P) criterion is fulfilled.

Physical properties

Hexamethyldisiloxane is a colorless and transparent liquid. It is easily deliquescent, flammable, and has the risk of causing combustion when exposed to high heat, open flame, and strong oxidizing agents. Boiling point 99.5℃. Flash point -1.1℃. Relative density (d2525) 0.7606. refractive index 1.3750. insoluble in water, soluble in many organic solvents.

Uses

Hexamethyldisiloxane is used as a base fluid in a wide range of personal care products that require fast evaporation and high spreadability. When blended with Dimethicone fluids, It can adjust the residence time of the silicone on the skin. Unlike other volatile fluids, Hexamethyldisiloxane Fluid does not cool the skin as it evaporates. Hexamethyldisiloxane is used as a carrying agent and diluent in the following: skin cream lotions, bath oils, suntan lotions, nail polishes, antiperspirants, deodorants, hair sprays and other beauty and hair care products.
A silicon based compound that can be used to create potentially biocompatible materials.
Used as a monomer in the synthesis of long chain polysiloxane structures.
Used in the methylation of mercury(II) salts.

Uses

The most popular precursor chemical is hexamethyldisiloxane (HMDS) which with the addition of helium and oxygen will produce a silica coating. it is used in a variety of consumer applications and can be used as intermediates in the production of silicone polymers.

Uses

Hexamethyldisiloxane can be used as silylating agent for carboxylic acids, and alcohols; used in preparation of aroyl chlorides; precursor for a variety of trimethylsilyl derivatives.Hexamethyldisiloxane has been used as an inexpensive starting material for the preparation of numerous synthetically useful trimethylsilyl derivatives.

Production Methods

Produced via acid hydrolysis of chlorotrimethylsilane and purification by distillation.

Definition

ChEBI: Hexamethyldisiloxane is an organosiloxane consisting of two trimethylsilyl groups covalently bound to a central oxygen.

Preparation

Synthesis of hexamethyldisiloxane by hydrolysis of trimethylsilyl chloride, water and sodium hydroxide.

General Description

Hexamethyldisiloxane (HMDSO), a linear polydisiloxane, is an organosilicon reagent commonly utilized as a source for plasma enhanced chemical vapor deposition (PE-CVD) of thin films of silicon compounds. It is also employed as a substitute to silane in silicon integrated circuit technology. Its dissociative ionization by electron impact has been studied by Fourier transform mass spectrometry. Synthesis of plasma-polymerized HMDSO thin films by atmospheric pressure glow (APG) discharge has been reported. Crystals of HMDSO at 148K are monoclinic. Addition of HMDSO to P4S10, improves its efficiency as thionating agent.

Flammability and Explosibility

Highly flammable

Purification Methods

Fractionally distil through a column packed with glass helices with ca 15 theoretical 20 1.3777. plates. It is highly flammable and is an irritant. [Mills & McKenzie J Am Chem Soc 76 2672 1954, Csakvari et al. J Organometal Chem 107 287 1976, Beilstein 4 IV 4018.]

Hexamethyldisiloxane Preparation Products And Raw materials

Raw materials

N-Methylaniline 101 Chlorotrimethylsilane

Preparation Products

Iodotrimethylsilane 5-(CHLOROMETHYL)-2-(TRIFLUOROMETHYL)THIAZOLE (2-(TRIFLUOROMETHYL)THIAZOL-5-YL)METHANOL 2-BROMO-1-(2-(TRIFLUOROMETHYL)THIAZOL-5-YL)ETHANONE ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBALDEHYDE Xanthophyll
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View Lastest Price from Hexamethyldisiloxane manufacturers

Ningxia Jinhua Chemical Co.,Ltd
Product
Hexamethyldisiloxane(HMDO) 107-46-0
Price
US $0.00/Kg/Drum
Min. Order
25Kg/Drum
Purity
99%
Supply Ability
200 tons
Release date
2020-08-07
Hebei Weibang Biotechnology Co., Ltd
Product
Hexamethyldisiloxane 107-46-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-01
Hebei Yanxi Chemical Co., Ltd.
Product
Hexamethyldisiloxane 107-46-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100tons
Release date
2023-08-11

107-46-0, HexamethyldisiloxaneRelated Search:

Chlorodimethylphenylsilane POLY(DIMETHYLSILOXANE), HYDROXY TERMINATED Dichlorodimethylsilane DODECAMETHYLCYCLOHEXASILOXANE Hexamethylcyclotrisiloxane Hexamethyldisilazane Dimethicone tert-Butyl methyl ether Dimethyldimethoxysilane Dimethyl disulfide POLYDIMETHYLSILOXANE 1,3-Bis(trimethylsilyl)urea Octamethylcyclotetrasiloxane Lithium bis(trimethylsilyl)amide BIS(TRIMETHYLSILYL) SULFIDE Hexamethyldisilane Heptamethyldisilazane Methyltriethoxysilane

  • os10
  • oxybis(trimethyl-silan
  • Oxybis(trimethylsilane)
  • Silane, oxybis(trimethyl)-
  • sws-f221
  • SILICONE FLUID
  • 2,2,4,4-TETRAMETHYL-3-OXA-2,4-DISILAPENTANE
  • HMDO
  • HMDSO
  • HEXAMETHYLDISILOXANE
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  • HEXAMETHYLDISILOXANE, 98+%
  • HEXAMETHYLDISILOXANE, 99.5+%, NMR GRADE
  • HEXAMETHYLDISILOXANE, FOR NMR-SPECTROS-C OPY
  • POLY(DIMETHYLSILOXANE), 200 FLUID, VISCO SITY 0.65 CST
  • HEXAMETHYLDISILOXANE 99+%
  • DISILOXANE
  • HEXAMETHYLDISILOXANE, NMR GRADE 99.7%
  • Hexamethyldisiloxane "HMDSO" 97%
  • HEXAMETHYLDISILOXANE (HMDS)
  • HEXAMETHYLDISILOXANE FOR SYNTHESIS
  • HMDO)HexaMethyldisilox
  • HexaMethyldisiloxane NMR grade, >=99.5%
  • HexaMethyldisiloxane puriss., >=98.5% (GC)
  • HexaMethyldisiloxane, 99.7%, NMR grade
  • Glipoxan
  • HX 18
  • KF 96L0.65
  • NSC 43346
  • PSF-0.65cSt
  • SF 0.65
  • SH 200-0.65CS
  • SH 200-0.65cSt
  • Volasil DM 0.65
  • Volasil DM 0.65SP
  • Hexamethyldisiloxane viscosity 0.65 cSt (25 C)
  • Hexamethyldisioxane
  • Hexamethyldisiloxane, 99.5%
  • ((CH3)3Si)2O
  • 1,1,1,3,3,3-Hexamethyldisiloxane
  • 1,1,1,3,3,3-Hexamethyl-disiloxane
  • belsildm0.65
  • Bis(trimethylsilyl) oxide
  • bis(trimethylsilyl)oxide
  • Disiloxane, 1,1,1,3,3,3-hexamethyl-
  • Hexamethyl Disiloxane (HMDSO) ( CAS No. : )
  • CFS-460 >=99%
  • 0.65cst Silicone Oil/Hexamethyldisiloxane
  • Hexamethyldisiloxane,NMRgrade
  • Silicone A
  • HEXAMETHYLDISILOXANE NMR GRADE: 99.9%
  • POLYDIMETHYLSILOXANE, TRIMETHYLSILOXY TERMINATED: VISCOSITY 0.65 CST.
  • HEXAMETHYLDISILOXANE PURE 99%
  • bis-trimethylsilyloxide
  • CH7310
  • DC 200 FLUID
  • Disiloxane,hexamethyl-
  • Fluka AG