ChemicalBook > CAS DataBase List > Hexamethyldisiloxane

Hexamethyldisiloxane

Product Name
Hexamethyldisiloxane
CAS No.
107-46-0
Chemical Name
Hexamethyldisiloxane
Synonyms
HMDSO;HMDO;DISILOXANE;1,1,1,3,3,3-Hexamethyldisiloxane;SILICONE FLUID;Fluka AG;Hexamethylene disiloxane;hexamethyldisiloxane(hmdo);os10;HX 18
CBNumber
CB2446352
Molecular Formula
C6H18OSi2
Formula Weight
162.38
MOL File
107-46-0.mol
More
Less

Hexamethyldisiloxane Property

Melting point:
−59 °C(lit.)
Boiling point:
101 °C(lit.)
Density 
0.764 g/mL at 20 °C(lit.)
vapor density 
>1 (vs air)
vapor pressure 
20 hPa (20 °C)
refractive index 
n20/D 1.377(lit.)
Flash point:
33 °F
storage temp. 
Store below +30°C.
solubility 
0.00037g/l insoluble
form 
liquid
color 
Colorless to Almost colorless
Specific Gravity
0.76
explosive limit
0.5-21.8%(V)
Water Solubility 
insoluble
Hydrolytic Sensitivity
1: no significant reaction with aqueous systems
BRN 
1736258
Dielectric constant
2.2（20℃）
Stability:
Stable, but moisture sensitive. Highly flammable. Incompatible with strong acids, strong bases, oxidizing agents.
InChIKey
UQEAIHBTYFGYIE-UHFFFAOYSA-N
LogP
5.06 at 20℃
CAS DataBase Reference
107-46-0(CAS DataBase Reference)
NIST Chemistry Reference
Disiloxane, hexamethyl-(107-46-0)
EPA Substance Registry System
Hexamethyldisiloxane (107-46-0)
More
Less

Safety

Hazard Codes 
F,N,T
Risk Statements 
11-50/53-65-51/53-48/23/24/25-36/38-46-45
Safety Statements 
16-61-62-45-26-53
RIDADR 
UN 1993 3/PG 2
WGK Germany 
3
RTECS 
JM9237000
F 
10
Autoignition Temperature
340 °C
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29310095
Hazardous Substances Data
107-46-0(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: > 12160 mg/kg LD50 dermal Rat > 2000 mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P273Avoid release to the environment.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.14051
Product name
Hexamethyldisiloxane
Purity
for synthesis
Packaging
100mL
Price
$43
Updated
2024/03/01
Sigma-Aldrich
Product number
8.14051
Product name
Hexamethyldisiloxane
Purity
for synthesis
Packaging
500mL
Price
$166
Updated
2024/03/01
TCI Chemical
Product number
H0091
Product name
Hexamethyldisiloxane
Purity
>98.0%(GC)
Packaging
25mL
Price
$17
Updated
2024/03/01
TCI Chemical
Product number
H0091
Product name
Hexamethyldisiloxane
Purity
>98.0%(GC)
Packaging
100mL
Price
$20
Updated
2024/03/01
Alfa Aesar
Product number
A11848
Product name
Hexamethyldisiloxane, 98+%
Packaging
100ml
Price
$25.65
Updated
2024/03/01
More
Less

Hexamethyldisiloxane Chemical Properties,Usage,Production

Chemical Properties

Hexamethyldisiloxane (HMDS) is a colorless or yellowish transparent liquid with a measured melting point of -68.2°C and a measured boiling point of 100.5°C at 1013 hPa. The measured vapor pressure is 44.51 hPa at 20 oC. The measured water solubility is 0.93 ± 0.63 mg/L at 23 oC. The measured log Kow of HMDS is 5.20 at 20 oC. Estimated log Koc values using EPISuite v 4.10 range from 2.5 (MCI method) to 4.5 (Kow method). As Episuite does not contain fragments for siloxanes for log Koc predictions, these values should be treated with caution. The potential for hydrolysis of the test substance may have influenced the determination of partition coefficient and water solubility.

Physical properties

Hexamethyldisiloxane is a colorless and transparent liquid. It is easily deliquescent, flammable, and has the risk of causing combustion when exposed to high heat, open flame, and strong oxidizing agents. Boiling point 99.5℃. Flash point -1.1℃. Relative density (d2525) 0.7606. refractive index 1.3750. insoluble in water, soluble in many organic solvents.

Uses

The most popular precursor chemical is hexamethyldisiloxane (HMDS) which with the addition of helium and oxygen will produce a silica coating. it is used in a variety of consumer applications and can be used as intermediates in the production of silicone polymers.

Uses

Hexamethyldisiloxane is used as a base fluid in a wide range of personal care products that require fast evaporation and high spreadability. When blended with Dimethicone fluids, It can adjust the residence time of the silicone on the skin. Unlike other volatile fluids, Hexamethyldisiloxane Fluid does not cool the skin as it evaporates. Hexamethyldisiloxane is used as a carrying agent and diluent in the following: skin cream lotions, bath oils, suntan lotions, nail polishes, antiperspirants, deodorants, hair sprays and other beauty and hair care products.
A silicon based compound that can be used to create potentially biocompatible materials.
Used as a monomer in the synthesis of long chain polysiloxane structures.
Used in the methylation of mercury(II) salts.

Uses

Hexamethyldisiloxane can be used as silylating agent for carboxylic acids, and alcohols; used in preparation of aroyl chlorides; precursor for a variety of trimethylsilyl derivatives.Hexamethyldisiloxane has been used as an inexpensive starting material for the preparation of numerous synthetically useful trimethylsilyl derivatives.

Preparation

Synthesis of hexamethyldisiloxane by hydrolysis of trimethylsilyl chloride, water and sodium hydroxide.

Definition

ChEBI: Hexamethyldisiloxane is an organosiloxane consisting of two trimethylsilyl groups covalently bound to a central oxygen.

Production Methods

Produced via acid hydrolysis of chlorotrimethylsilane and purification by distillation.

General Description

Hexamethyldisiloxane (HMDSO), a linear polydisiloxane, is an organosilicon reagent commonly utilized as a source for plasma enhanced chemical vapor deposition (PE-CVD) of thin films of silicon compounds. It is also employed as a substitute to silane in silicon integrated circuit technology. Its dissociative ionization by electron impact has been studied by Fourier transform mass spectrometry. Synthesis of plasma-polymerized HMDSO thin films by atmospheric pressure glow (APG) discharge has been reported. Crystals of HMDSO at 148K are monoclinic. Addition of HMDSO to P4S10, improves its efficiency as thionating agent.

Flammability and Explosibility

Highly flammable

Purification Methods

Fractionally distil through a column packed with glass helices with ca 15 theoretical 20 1.3777. plates. It is highly flammable and is an irritant. [Mills & McKenzie J Am Chem Soc 76 2672 1954, Csakvari et al. J Organometal Chem 107 287 1976, Beilstein 4 IV 4018.]

Hexamethyldisiloxane Preparation Products And Raw materials

Raw materials

N-Methylaniline 101 Chlorotrimethylsilane

Preparation Products

Iodotrimethylsilane 5-(CHLOROMETHYL)-2-(TRIFLUOROMETHYL)THIAZOLE (2-(TRIFLUOROMETHYL)THIAZOL-5-YL)METHANOL 2-BROMO-1-(2-(TRIFLUOROMETHYL)THIAZOL-5-YL)ETHANONE ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBALDEHYDE Xanthophyll
More
Less

Hexamethyldisiloxane Suppliers

Americas 1 Belgium 2 Canada 4 China 359 Europe 3 France 1 Germany 8 India 33 Italy 1 Japan 5 Russia 3 Singapore 1 Slovakia 1 South Korea 2 Spain 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 12 United States 67 Global 508
Shanghai TongYuan Chemical Co., Ltd.
Tel
021-021-69182866 13701855675
Fax
021-69182022
Email
tongyuanchem@126.com
Country
China
ProdList
4331
Advantage
58
Hebei Jiacheng Trading Co., LTD
Tel
15031159310
Email
1301448869@qq.com
Country
China
ProdList
8
Advantage
58
Wuhan canos Technology Co., Ltd
Tel
027-83238443 15327105076
Fax
027-83238443
Email
926254131@qq.com
Country
China
ProdList
3011
Advantage
58
Condice Chemical (Hubei) Co., Ltd.
Tel
18064039730
Email
3127859172@qq.com
Country
China
ProdList
2831
Advantage
58
tonsooh
Tel
027-83238443 13343438265
Fax
027-83238443
Email
1569708153@qq.com
Country
China
ProdList
4994
Advantage
58
Zhangjiagang Xinya Chemical Co., Ltd.
Tel
0512-58980899 13915696858
Email
sales@zjgxinyachem.com
Country
China
ProdList
27
Advantage
58
Iota silicone oil (Anhui) Co.,ltd.
Tel
18055252352
Email
sales08@siliconeoil.net
Country
China
ProdList
484
Advantage
58
HUANGSHANJIAHUASILICONE CO,LTD
Tel
15212785412; 15212785412
Email
hsuzihang@163.com
Country
China
ProdList
71
Advantage
58
Hubei coward Chemical Co., Ltd
Tel
13125172151
Email
3508116617@qq.com
Country
China
ProdList
4561
Advantage
58
Shanghai Pengping Biotechnology Co., Ltd
Tel
13585874280
Email
longhealth0604@163.com
Country
China
ProdList
75
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Secco work (Beijing) chemical technology co., LTD
Tel
0566-8928158
Fax
010-69755668
Email
343367102@QQ.COM
Country
China
ProdList
360
Advantage
54
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Wuhan Kemi-Works Chemical Co., Ltd
Tel
027-85736489
Fax
86-27-85736485
Email
info@kemiworks.net
Country
China
ProdList
542
Advantage
57
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4388
Advantage
65
Aemon Chemical
Tel
0086-755-86198205
Email
acinfo@aemonchem.com
Country
China
ProdList
1937
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9725
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9900
Advantage
58
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18216
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
Shanghai chuqing Organosilane technology ltd
Tel
021-61530618
Fax
86-21-51714575
Email
sales@chuqingtech.com
Country
China
ProdList
274
Advantage
55
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9552
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4576
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3750
Advantage
55
Zouping Mingxing Chemical Co.,Ltd.
Tel
86-13605431940 13605431940
Fax
0086-0543-2240079
Email
zpmxchemical@126.com
Country
China
ProdList
2002
Advantage
62
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3933
Advantage
58
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3585
Advantage
55
RiZhao LiDeShi Chemical Co., Ltd.
Tel
010-51268198
Fax
010-63833209
Email
leadershipchem@126.com
Country
China
ProdList
2549
Advantage
58
Shanghai Gileader Advanced Material Technology Co.,Ltd
Tel
021-69980372 18516111942
Email
823898732@qq.com
Country
China
ProdList
1336
Advantage
56
More
Less

View Lastest Price from Hexamethyldisiloxane manufacturers

Ningxia Jinhua Chemical Co.,Ltd
Product
Hexamethyldisiloxane(HMDO) 107-46-0
Price
US $0.00/Kg/Drum
Min. Order
25Kg/Drum
Purity
99%
Supply Ability
200 tons
Release date
2020-08-07
Henan Fengda Chemical Co., Ltd
Product
Hexamethyldisiloxane 107-46-0
Price
US $50.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-22
Hebei Duling International Trade Co. LTD
Product
Hexamethyldisioxane 107-46-0
Price
US $100.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
100 tons
Release date
2022-09-23

107-46-0, HexamethyldisiloxaneRelated Search:

Chlorodimethylphenylsilane POLY(DIMETHYLSILOXANE), HYDROXY TERMINATED Dichlorodimethylsilane DODECAMETHYLCYCLOHEXASILOXANE Hexamethylcyclotrisiloxane Hexamethyldisilazane Dimethicone tert-Butyl methyl ether Dimethyldimethoxysilane Dimethyl disulfide POLYDIMETHYLSILOXANE 1,3-Bis(trimethylsilyl)urea Octamethylcyclotetrasiloxane Lithium bis(trimethylsilyl)amide BIS(TRIMETHYLSILYL) SULFIDE Hexamethyldisilane Heptamethyldisilazane Methyltriethoxysilane

  • os10
  • oxybis(trimethyl-silan
  • Oxybis(trimethylsilane)
  • Silane, oxybis(trimethyl)-
  • sws-f221
  • SILICONE FLUID
  • 2,2,4,4-TETRAMETHYL-3-OXA-2,4-DISILAPENTANE
  • HMDO
  • HMDSO
  • HEXAMETHYLDISILOXANE
  • BIS(TRIMETHYLSILYL)ETHER
  • HEXAMETHYLDISILOXANE, 98+%
  • HEXAMETHYLDISILOXANE, 99.5+%, NMR GRADE
  • HEXAMETHYLDISILOXANE, FOR NMR-SPECTROS-C OPY
  • POLY(DIMETHYLSILOXANE), 200 FLUID, VISCO SITY 0.65 CST
  • HEXAMETHYLDISILOXANE 99+%
  • DISILOXANE
  • HEXAMETHYLDISILOXANE, NMR GRADE 99.7%
  • Hexamethyldisiloxane "HMDSO" 97%
  • HEXAMETHYLDISILOXANE (HMDS)
  • HEXAMETHYLDISILOXANE FOR SYNTHESIS
  • HMDO)HexaMethyldisilox
  • HexaMethyldisiloxane NMR grade, >=99.5%
  • HexaMethyldisiloxane puriss., >=98.5% (GC)
  • HexaMethyldisiloxane, 99.7%, NMR grade
  • Glipoxan
  • HX 18
  • KF 96L0.65
  • NSC 43346
  • PSF-0.65cSt
  • SF 0.65
  • SH 200-0.65CS
  • SH 200-0.65cSt
  • Volasil DM 0.65
  • Volasil DM 0.65SP
  • Hexamethyldisiloxane viscosity 0.65 cSt (25 C)
  • Hexamethyldisioxane
  • Hexamethyldisiloxane, 99.5%
  • ((CH3)3Si)2O
  • 1,1,1,3,3,3-Hexamethyldisiloxane
  • 1,1,1,3,3,3-Hexamethyl-disiloxane
  • belsildm0.65
  • Bis(trimethylsilyl) oxide
  • bis(trimethylsilyl)oxide
  • Disiloxane, 1,1,1,3,3,3-hexamethyl-
  • Hexamethyl Disiloxane (HMDSO) ( CAS No. : )
  • CFS-460 >=99%
  • 0.65cst Silicone Oil/Hexamethyldisiloxane
  • Hexamethyldisiloxane,NMRgrade
  • Silicone A
  • HEXAMETHYLDISILOXANE NMR GRADE: 99.9%
  • POLYDIMETHYLSILOXANE, TRIMETHYLSILOXY TERMINATED: VISCOSITY 0.65 CST.
  • HEXAMETHYLDISILOXANE PURE 99%
  • bis-trimethylsilyloxide
  • CH7310
  • DC 200 FLUID
  • Disiloxane,hexamethyl-
  • Fluka AG