endo BCN-O-PNB
- Product Name
- endo BCN-O-PNB
- CAS No.
- 1263166-91-1
- Chemical Name
- endo BCN-O-PNB
- Synonyms
- endo-BCN-PNP-carbonate;endo BCN-PNP;BCN-PNP (ENDO);endo BCN-O-PNP;endo BCN-O-PNB;endo-BCN-PNB ester;endo BCN - active ester (p-NPC);endo BCN - active ester (p-NPE);[(1R,8S)-9-bicyclo[6.1.0]non-4-ynyl]methyl (4-nitrophenyl) carbonate;((1R,8S,9S)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl 4-nitrophenyl carbonate
- CBNumber
- CB24665283
- Molecular Formula
- C17H17NO5
- Formula Weight
- 315.33
- MOL File
- 1263166-91-1.mol
endo BCN-O-PNB Property
- Boiling point:
- 475.7±37.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- Storage temp. -20°C
- solubility
- DMSO : 100 mg/mL (317.14 mM; Need ultrasonic)
- form
- Solid
- color
- White to off-white
- InChI
- InChI=1/C17H17NO5/c19-17(23-13-9-7-12(8-10-13)18(20)21)22-11-16-14-5-3-1-2-4-6-15(14)16/h7-10,14-16H,3-6,11H2/t14-,15+,16-
- InChIKey
- QXNXOXMDBLHIDB-MUJYYYPQNA-N
- SMILES
- C([C@H]1[C@@]2([H])CCC#CCC[C@@]12[H])OC(=O)OC1C=CC(N(=O)=O)=CC=1 |&1:1,2,10,r|
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-20506
- Product name
- endo-BCN-PNP-carbonate
- Purity
- 95%
- Packaging
- 50mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- BP-20506
- Product name
- endo-BCN-PNP-carbonate
- Purity
- 95%
- Packaging
- 250mg
- Price
- $940
- Updated
- 2021/12/16
- Product number
- BP-20506
- Product name
- endo-BCN-PNP-carbonate
- Purity
- 95%
- Packaging
- 1g
- Price
- $1980
- Updated
- 2021/12/16
endo BCN-O-PNB Chemical Properties,Usage,Production
Description
endo-BCN-PNP-carbonate is a very reactive compound which can easily react with amine-containing molecules in organic solvents. PNP is a good leaving group. The BCN is used for copper-free Click Chemistry reactions.
Uses
endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50
Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
endo BCN-O-PNB Preparation Products And Raw materials
Raw materials
Preparation Products
endo BCN-O-PNB Suppliers
- Tel
- +1-5166625404;
- Fax
- 1-516-927-0118
- Info@alfa-chemistry.com
- Country
- United States
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- 20405
- Advantage
- 58
- Tel
- +1-631-485-4226
- Fax
- 1-631-614-7828
- inquiry@bocsci.com
- Country
- United States
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- 19552
- Advantage
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- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 57505
- Advantage
- 58
View Lastest Price from endo BCN-O-PNB manufacturers
- Product
- endo BCN-O-PNB 1263166-91-1
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-20