ChemicalBook > CAS DataBase List > 1-(4-Bromo-2-fluorophenyl)ethanone

1-(4-Bromo-2-fluorophenyl)ethanone

Product Name
1-(4-Bromo-2-fluorophenyl)ethanone
CAS No.
625446-22-2
Chemical Name
1-(4-Bromo-2-fluorophenyl)ethanone
Synonyms
2-Fluoro-4-bromoacetophenone;4-BROMO-2-FLUOROACETOPHENONE;4'-Bromo-2'-fluoroacetophenone;1-Acetyl-4-bromo-2-fluorobenzene;4'-Bromo-2'-fluoroacetophenone98%;4'-Bromo-2'-fluoroacetophenone 98%;4'-Bromo-2'-fluoroacetophenone,96%;1-(4-bromo-2-fluorophenyl)ethanone;Ethanone, 1-(4-broMo-2-fluorophenyl)-;1-(4-broMophenyl)-2-fluoroethan-1-one
CBNumber
CB2470687
Molecular Formula
C8H6BrFO
Formula Weight
217.04
MOL File
625446-22-2.mol
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1-(4-Bromo-2-fluorophenyl)ethanone Property

Melting point:
23 °C
Boiling point:
256.3±25.0 °C(Predicted)
Density 
1.535±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Acetonitrile (Slightly), Chloroform (Slightly)
form 
Solid
color 
White to Off-White
InChI
InChI=1S/C8H6BrFO/c1-5(11)7-3-2-6(9)4-8(7)10/h2-4H,1H3
InChIKey
ASKFCSCYGAFWAB-UHFFFAOYSA-N
SMILES
C(=O)(C1=CC=C(Br)C=C1F)C
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-36
Safety Statements 
26-36/37/39
Hazard Note 
Irritant
HS Code 
2914790090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SYX00307
Product name
4-Bromo-2-fluoroacetophenone
Packaging
1g
Price
$185
Updated
2025/07/31
TCI Chemical
Product number
B5236
Product name
4'-Bromo-2'-fluoroacetophenone
Purity
>98.0%(GC)
Packaging
1g
Price
$67
Updated
2025/07/31
TCI Chemical
Product number
B5236
Product name
4'-Bromo-2'-fluoroacetophenone
Purity
>98.0%(GC)
Packaging
5g
Price
$198
Updated
2025/07/31
TRC
Product number
A168813
Product name
1-Acetyl-4-bromo-2-fluorobenzene
Packaging
1g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
J97143
Product name
4'-Bromo-2'-fluoroacetophenone
Packaging
1g
Price
$20
Updated
2021/12/16
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1-(4-Bromo-2-fluorophenyl)ethanone Chemical Properties,Usage,Production

Synthesis

To a solution of 4-bromo-2-fluoro-N-methoxy-N-methylbenzamide (13 g, 46 mmol) in THF (4.0 mL) was added dropwise methylmagnesium bromide (3M ethyl ether solution, 30 mL, 91 mmol) at 0°C, and the mixture was stirred at room temperature for 3 hr. For the reaction mixture, saturated aqueous ammonium chloride solution, and the mixture was extracted with ethyl acetate. The obtained extract was washed with water and saturated brine, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to give 4-Bromo-2-fluoroacetophenone as a pale yellow oil.

References

[1] Patent: US2008/45556, 2008, A1. Location in patent: Page/Page column 32
[2] Patent: US2011/118257, 2011, A1. Location in patent: Page/Page column 97-98
[3] Patent: US2011/281865, 2011, A1. Location in patent: Page/Page column 85-86
[4] Patent: WO2011/145035, 2011, A1. Location in patent: Page/Page column 114-115
[5] Journal of Medicinal Chemistry, 2008, vol. 51, # 2, p. 282 - 297

1-(4-Bromo-2-fluorophenyl)ethanone Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-Bromo-2-fluorophenyl)ethanone Suppliers

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View Lastest Price from 1-(4-Bromo-2-fluorophenyl)ethanone manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
1-(4-Bromo-2-fluorophenyl)ethanone 625446-22-2
Price
US $1.10-9.90/KG
Min. Order
1KG
Purity
99% min
Supply Ability
100kg
Release date
2025-08-18
WUHAN FORTUNA CHEMICAL CO., LTD
Product
4'-Bromo-2'-fluoroacetophenone 625446-22-2
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-22
Hebei Chuanghai Biotechnology Co., Ltd
Product
4-BROMO-2-FLUOROACETOPHENONE 625446-22-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-11

625446-22-2, 1-(4-Bromo-2-fluorophenyl)ethanoneRelated Search:

3'-Bromo-4'-fluoroacetophenone97%,3- BROMO-4-FLUOROACETOPHENONE 98+%,3-BROMO-4-FLUOROACETOPHENONE,3'-BROMO-4'-FLUOROACETOPHENONE ALPHA,ALPHA-DIBROMO-4-FLUOROACETOPHENONE ALPHA-BROMO-3-FLUOROACETOPHENONE,2-BROMO-3'-FLUOROACETOPHENONE 2'-BROMO-5'-FLUOROACETOPHENONE 2-BROMO-2'-FLUOROACETOPHENONE 2-Bromo-4'-fluoroacetophenone 2'-Bromo-4'-fluoroacetophenone 97%,2'-Bromo-4'-fluoroacetophenone97% 3'-Bromo-2'-Fluoroacetophenone 1-(4-Bromo-2-fluorophenyl)ethanone 4-BROMO-2-FLUORO-3'-PYRROLIDINOMETHYL BENZOPHENONE 4-BROMO-2-FLUORO-3'-PIPERIDINOMETHYL BENZOPHENONE 4-BROMO-2-FLUORO-4'-THIOMORPHOLINOMETHYL BENZOPHENONE 4-BROMO-2-FLUORO-4'-PYRROLIDINOMETHYL BENZOPHENONE 4-BROMO-2-FLUOROPHENYL CYCLOPENTYL KETONE 4-BROMO-2-FLUOROPHENYL CYCLOPROPYL KETONE 4'-BROMO-2,2-DIMETHYL-2'-FLUOROPROPIOPHENONE 4-BROMO-2-FLUORO-3'-MORPHOLINOMETHYL BENZOPHENONE 4-BROMO-2-FLUORO-4'-MORPHOLINOMETHYL BENZOPHENONE

  • 1-Acetyl-4-bromo-2-fluorobenzene
  • 1-(4-Bromo-2-fluorophenyl)ethan-1-one
  • 1-(4-broMophenyl)-2-fluoroethan-1-one
  • Ethanone, 1-(4-broMo-2-fluorophenyl)-
  • 4-Bromo-2-fluoroacetophenone/2-Fluoro-4-bromoacetophenone
  • 4'-Bromo-2'-fluoroacetophenone 98%
  • 4'-Bromo-2'-fluoroacetophenone98%
  • 4-BROMO-2-FLUOROACETOPHENONE
  • 2-Fluoro-4-bromoacetophenone
  • 4'-Bromo-2'-fluoroacetophenone,96%
  • 4'-Bromo-2'-fluoroacetophenone
  • 1-(4-bromo-2-fluorophenyl)ethanone
  • 625446-22-2
  • 625446-22-5
  • Fluorine series
  • Adehydes, Acetals & Ketones
  • Bromine Compounds
  • Fluorine Compounds