ChemicalBook > CAS DataBase List > 1-(4-Bromo-2-fluorophenyl)ethanone

1-(4-Bromo-2-fluorophenyl)ethanone

Product Name
1-(4-Bromo-2-fluorophenyl)ethanone
CAS No.
625446-22-2
Chemical Name
1-(4-Bromo-2-fluorophenyl)ethanone
Synonyms
2-Fluoro-4-bromoacetophenone;4-BROMO-2-FLUOROACETOPHENONE;4'-Bromo-2'-fluoroacetophenone;1-Acetyl-4-bromo-2-fluorobenzene;4'-Bromo-2'-fluoroacetophenone98%;4'-Bromo-2'-fluoroacetophenone 98%;4'-Bromo-2'-fluoroacetophenone,96%;1-(4-bromo-2-fluorophenyl)ethanone;Ethanone, 1-(4-broMo-2-fluorophenyl)-;1-(4-broMophenyl)-2-fluoroethan-1-one
CBNumber
CB2470687
Molecular Formula
C8H6BrFO
Formula Weight
217.04
MOL File
625446-22-2.mol
More
Less

1-(4-Bromo-2-fluorophenyl)ethanone Property

Melting point:
23 °C
Boiling point:
256.3±25.0 °C(Predicted)
Density 
1.535±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Acetonitrile (Slightly), Chloroform (Slightly)
form 
Solid
color 
White to Off-White
InChI
InChI=1S/C8H6BrFO/c1-5(11)7-3-2-6(9)4-8(7)10/h2-4H,1H3
InChIKey
ASKFCSCYGAFWAB-UHFFFAOYSA-N
SMILES
C(=O)(C1=CC=C(Br)C=C1F)C
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-36
Safety Statements 
26-36/37/39
Hazard Note 
Irritant
HS Code 
2914790090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SYX00307
Product name
4-Bromo-2-fluoroacetophenone
Packaging
1g
Price
$185
Updated
2025/07/31
TCI Chemical
Product number
B5236
Product name
4'-Bromo-2'-fluoroacetophenone
Purity
>98.0%(GC)
Packaging
1g
Price
$67
Updated
2025/07/31
TCI Chemical
Product number
B5236
Product name
4'-Bromo-2'-fluoroacetophenone
Purity
>98.0%(GC)
Packaging
5g
Price
$198
Updated
2025/07/31
TRC
Product number
A168813
Product name
1-Acetyl-4-bromo-2-fluorobenzene
Packaging
1g
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
2617-B-X2
Product name
4'-Bromo-2'-fluoroacetophenone
Purity
98%
Packaging
1g
Price
$85
Updated
2021/12/16
More
Less

1-(4-Bromo-2-fluorophenyl)ethanone Chemical Properties,Usage,Production

Synthesis

To a solution of 4-bromo-2-fluoro-N-methoxy-N-methylbenzamide (13 g, 46 mmol) in THF (4.0 mL) was added dropwise methylmagnesium bromide (3M ethyl ether solution, 30 mL, 91 mmol) at 0°C, and the mixture was stirred at room temperature for 3 hr. For the reaction mixture, saturated aqueous ammonium chloride solution, and the mixture was extracted with ethyl acetate. The obtained extract was washed with water and saturated brine, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to give 4-Bromo-2-fluoroacetophenone as a pale yellow oil.

References

[1] Patent: US2008/45556, 2008, A1. Location in patent: Page/Page column 32
[2] Patent: US2011/118257, 2011, A1. Location in patent: Page/Page column 97-98
[3] Patent: US2011/281865, 2011, A1. Location in patent: Page/Page column 85-86
[4] Patent: WO2011/145035, 2011, A1. Location in patent: Page/Page column 114-115
[5] Journal of Medicinal Chemistry, 2008, vol. 51, # 2, p. 282 - 297

1-(4-Bromo-2-fluorophenyl)ethanone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-(4-Bromo-2-fluorophenyl)ethanone Suppliers

Americas 1 China 170 Europe 1 Germany 2 India 3 Italy 1 Japan 1 United Kingdom 6 United States 14 Global 199
Hangzhou Zhixi Biomedical Technology Co., Ltd.
Tel
17769852855 15268498003
Email
602732428@qq.com
Country
China
ProdList
21
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
021-31038972,31038973 17321035817
Fax
+86-21-51385350
Email
sales@harvest-chem.com
Country
China
ProdList
2816
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16075
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Beijing Eternalchem Co,. Ltd.
Tel
010-59484199 18611897322
Email
sales@eternalchem.com
Country
China
ProdList
4383
Advantage
60
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
Wuhan ariel chemical Co., LTD.
Tel
18986259541
Fax
027-87840182
Email
sales@3stc.com
Country
China
ProdList
3764
Advantage
58
Tianjin Jinyuda Chemical Co., Ltd.
Tel
022-58013646 13011382049
Fax
022-23854368
Email
sales@jinyudachem.com
Country
China
ProdList
1930
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Shanghai ZaiQi Bio-Tech Co., Ltd.
Tel
021-54824098, 021-37212705 021-37212706, 13391256916
Fax
021-54824069
Email
sales@chemzq.com
Country
China
ProdList
570
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
Shanghai potentpharm CO.,Ltd
Tel
(86) 21 51969655
Fax
(86) 21 51969655， QQ：33109286， 263541193
Country
China
ProdList
487
Advantage
22
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2864
Advantage
52
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Shanghai Huikai Chemical Technology Co., Ltd.
Tel
021-61995394 18916691159
Email
chemicalsea@163.com
Country
China
ProdList
1972
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9476
Advantage
58
Suzhou Laing Biological Technology Co., LTD
Tel
0512-62968256 18550502935
Fax
0512-62968256
Email
export@laingbiotec.com
Country
China
ProdList
981
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9637
Advantage
58
Chemfun Medical Technology(Shanghai) Co., Ltd.
Tel
021-67220633 021-54824098
Fax
+86-21-54824069
Email
chemfun@chemfun.net
Country
China
ProdList
491
Advantage
58
ShangHai KenEn Chemical Technology Co., Ltd.
Tel
13120367189
Fax
021-50315529
Email
mychess007@163.com
Country
China
ProdList
1994
Advantage
55
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ：3154870176
Email
mafarm@126.com
Country
China
ProdList
4542
Advantage
58
Tianjin Anhao Biological Technology Co., Ltd.
Tel
Email
sales@ahpharmatech.com
Country
China
ProdList
5734
Advantage
55
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8144
Advantage
55
Shanghai Jovan Biochemical Technology Co. Ltd.
Tel
+86-021-61654350
Fax
+86-021-61654350
Email
1245958370@qq.com
Country
China
ProdList
2982
Advantage
50
Changzhou Tianrui Pharmaceutical Technology Co., Ltd.
Tel
0519-85386832 13382812559
Fax
0519-85386832
Email
sales@cztrchem.com
Country
China
ProdList
1185
Advantage
56
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 18626450290
Email
yftan@aikonchem.com
Country
China
ProdList
16679
Advantage
50
Shanghai Rong Lin Medical Technology Co., Ltd.
Tel
18602194589
Email
lincy-110@163.com
Country
China
ProdList
863
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Changzhou Anxuan Chemical, Co., Ltd.
Tel
13912302692 13912302692;
Fax
0519-88064678
Email
sales@anxuanchem.com
Country
China
ProdList
4828
Advantage
58
Struchem Co., Ltd.
Tel
0512-63009836 18994340901
Fax
0512-63006936
Email
helen@struchem.com
Country
China
ProdList
3981
Advantage
60
SanoChem (Chengdu) Tech. Co., Ltd.
Tel
28-87999436 02887999436
Fax
QQ:2746983436
Email
sales@sano-chem.com
Country
China
ProdList
3795
Advantage
55
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
12000
Advantage
58
Hangzhou Copiore Chemical Co., Ltd.
Tel
0571-56501939;0571-56076030 13757145729
Fax
0571-56501939
Email
sales@copiore.com
Country
China
ProdList
299
Advantage
58
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20794
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
More
Less

View Lastest Price from 1-(4-Bromo-2-fluorophenyl)ethanone manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
1-(4-Bromo-2-fluorophenyl)ethanone 625446-22-2
Price
US $1.10-9.90/KG
Min. Order
1KG
Purity
99% min
Supply Ability
100kg
Release date
2025-08-18
WUHAN FORTUNA CHEMICAL CO., LTD
Product
4'-Bromo-2'-fluoroacetophenone 625446-22-2
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-22
Hebei Chuanghai Biotechnology Co., Ltd
Product
4-BROMO-2-FLUOROACETOPHENONE 625446-22-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-11

625446-22-2, 1-(4-Bromo-2-fluorophenyl)ethanoneRelated Search:

3'-Bromo-4'-fluoroacetophenone97%,3- BROMO-4-FLUOROACETOPHENONE 98+%,3-BROMO-4-FLUOROACETOPHENONE,3'-BROMO-4'-FLUOROACETOPHENONE ALPHA,ALPHA-DIBROMO-4-FLUOROACETOPHENONE ALPHA-BROMO-3-FLUOROACETOPHENONE,2-BROMO-3'-FLUOROACETOPHENONE 2'-BROMO-5'-FLUOROACETOPHENONE 2-BROMO-2'-FLUOROACETOPHENONE 2-Bromo-4'-fluoroacetophenone 2'-Bromo-4'-fluoroacetophenone 97%,2'-Bromo-4'-fluoroacetophenone97% 3'-Bromo-2'-Fluoroacetophenone 1-(4-Bromo-2-fluorophenyl)ethanone 4-BROMO-2-FLUORO-3'-PYRROLIDINOMETHYL BENZOPHENONE 4-BROMO-2-FLUORO-3'-PIPERIDINOMETHYL BENZOPHENONE 4-BROMO-2-FLUORO-4'-THIOMORPHOLINOMETHYL BENZOPHENONE 4-BROMO-2-FLUORO-4'-PYRROLIDINOMETHYL BENZOPHENONE 4-BROMO-2-FLUOROPHENYL CYCLOPENTYL KETONE 4-BROMO-2-FLUOROPHENYL CYCLOPROPYL KETONE 4'-BROMO-2,2-DIMETHYL-2'-FLUOROPROPIOPHENONE 4-BROMO-2-FLUORO-3'-MORPHOLINOMETHYL BENZOPHENONE 4-BROMO-2-FLUORO-4'-MORPHOLINOMETHYL BENZOPHENONE

  • 1-Acetyl-4-bromo-2-fluorobenzene
  • 1-(4-Bromo-2-fluorophenyl)ethan-1-one
  • 1-(4-broMophenyl)-2-fluoroethan-1-one
  • Ethanone, 1-(4-broMo-2-fluorophenyl)-
  • 4-Bromo-2-fluoroacetophenone/2-Fluoro-4-bromoacetophenone
  • 4'-Bromo-2'-fluoroacetophenone 98%
  • 4'-Bromo-2'-fluoroacetophenone98%
  • 4-BROMO-2-FLUOROACETOPHENONE
  • 2-Fluoro-4-bromoacetophenone
  • 4'-Bromo-2'-fluoroacetophenone,96%
  • 4'-Bromo-2'-fluoroacetophenone
  • 1-(4-bromo-2-fluorophenyl)ethanone
  • 625446-22-2
  • 625446-22-5
  • Fluorine series
  • Adehydes, Acetals & Ketones
  • Bromine Compounds
  • Fluorine Compounds