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Canakinumab

Product Name
Canakinumab
CAS No.
914613-48-2
Chemical Name
Canakinumab
Synonyms
ACZ885;Ilaris;ACZ-885;ACZ 885;Canakinumab;ACZ 885|||Ilaris;Canakinumab (Anti-IL-1b);Research Grade Canakinumab;Anti-Human IL-1B(Canakinumab);Research Grade Canakinumab(DHB95601)
CBNumber
CB24845962
Formula Weight
0
MOL File
Mol file
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Canakinumab Property

storage temp. 
Store at -20°C
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
ATB0023417
Product name
CANAKINUMAB
Purity
95.00%
Packaging
5MG
Price
$500.46
Updated
2021/12/16
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Canakinumab Chemical Properties,Usage,Production

Uses

Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC50 values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin[1][2].

References

[1] Dhimolea E. Canakinumab. MAbs. Epub 2010 Jan 15. DOI:10.4161/mabs.2.1.10328
[2] Rondeau JM, et al. The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1β. MAbs. 2015;7(6):1151-60. DOI:10.1080/19420862.2015.1081323

Canakinumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Canakinumab Suppliers

Chembest Research Laboratories Limited
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China
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BOC Sciences
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1-631-485-4226; 16314854226
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Country
United States
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
Fax
021-65675885
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China
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Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
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China
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71826
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ShangHai Biochempartner Co.,Ltd
Tel
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China
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Hubei Kele Fine Chemical Co., Ltd
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914613-48-2, CanakinumabRelated Search:


  • Canakinumab
  • Anti-Human IL-1B(Canakinumab)
  • Research Grade Canakinumab(DHB95601)
  • ACZ 885
  • ACZ885
  • ACZ-885
  • Ilaris
  • Canakinumab (Anti-IL-1b)
  • ACZ 885|||Ilaris
  • Research Grade Canakinumab
  • Canakinumab - in PBS buffer approx. 15mg/ml
  • 914613-48-2