ChemicalBook > CAS DataBase List > Canakinumab
Canakinumab
- Product Name
- Canakinumab
- CAS No.
- 914613-48-2
- Chemical Name
- Canakinumab
- Synonyms
- ACZ885;Ilaris;ACZ-885;ACZ 885;Canakinumab;ACZ 885|||Ilaris;Canakinumab (Anti-IL-1b);Research Grade Canakinumab;Anti-Human IL-1B(Canakinumab);Research Grade Canakinumab(DHB95601)
- CBNumber
- CB24845962
- Formula Weight
- 0
- MOL File
- Mol file
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Canakinumab Property
- storage temp.
- Store at -20°C
- form
- Liquid
- color
- Colorless to light yellow
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- ATB0023417
- Product name
- CANAKINUMAB
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.46
- Updated
- 2021/12/16
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Canakinumab Chemical Properties,Usage,Production
Uses
Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC50 values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin[1][2].
References
[1] Dhimolea E. Canakinumab. MAbs. Epub 2010 Jan 15. DOI:10.4161/mabs.2.1.10328
[2] Rondeau JM, et al. The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1β. MAbs. 2015;7(6):1151-60. DOI:10.1080/19420862.2015.1081323
Canakinumab Preparation Products And Raw materials
Raw materials
Preparation Products
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Canakinumab Suppliers
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 12952
- Advantage
- 65
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 57505
- Advantage
- 58
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