ChemicalBook > CAS DataBase List > Boc-L-2,4-diaminobutyric acid

Boc-L-2,4-diaminobutyric acid

Product Name: Boc-L-2,4-diaminobutyric acid
CAS No.: 25691-37-6
Chemical Name: Boc-L-2,4-diaminobutyric acid
Synonyms: BOC-DAB;BOC-DAB-OH;BOC-L-DAB-OH;N-alpha-Ac-Nγ(Tert-Butoxy)Carbonyl Dab-OH;BOC-L-2,4-DIAMINOBUTYRIC ACID;Boc-L-2,4-Dlaminobutyrlc Acid;N?Boc-L-2,4-diaminobutyric acid;Na-Boc-L-2,4-diaminobutyric acid;Nα-Boc-L-2,4-diaminobutyric acid
CBNumber: CB2486642
Molecular Formula: C9H18N2O4
Formula Weight: 218.25
MOL File: 25691-37-6.mol

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Boc-L-2,4-diaminobutyric acid Property

Melting point:: 192-194 °C
Boiling point:: 385.5±37.0 °C(Predicted)
Density: 1.160±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Methanol (Sparingly), Water (Slightly)
form: Powder
pka: 3?+-.0.10(Predicted)
color: White to off-white
optical activity: [α]/D +7.5±1°, c = 1 in methanol: water (1:1)
BRN: 4745487
CAS DataBase Reference: 25691-37-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 38-41
Safety Statements: 26-39
RIDADR: 3265
WGK Germany: 3
HS Code: 2922.49.8000
HazardClass: 8
PackingGroup: Ⅲ

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2515
Product name: (S)-4-Amino-2-(tert-butoxycarbonylamino)butyric Acid
Purity: >98.0%(T)
Packaging: 1g
Price: $65
Updated: 2021/12/16

TCI Chemical

Product number: A2515
Product name: (S)-4-Amino-2-(tert-butoxycarbonylamino)butyric Acid
Purity: >98.0%(T)
Packaging: 5g
Price: $336
Updated: 2025/07/31

TRC

Product number: B657100
Product name: Boc-L-2,4-diaminobutyricAcid
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Usbiological

Product number: 265137
Product name: N-alpha-Boc-L-2,4-diaminobutyric acid
Packaging: 500mg
Price: $333
Updated: 2021/12/16

Activate Scientific

Product number: AS38881
Product name: Boc-L-2,4-Diaminobutyric acid
Purity: 97% ee
Packaging: 1g
Price: $43
Updated: 2021/12/16

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Boc-L-2,4-diaminobutyric acid Chemical Properties,Usage,Production

Uses

Boc-L-2,4-diaminobutyric acid is a reagent used to synthesize somatostatin antagonist. It can also be used to develop blood coagulation factor Xa inhibitors.

Synthesis

13726-85-7

25691-37-6

General procedure for the synthesis of (S)-4-amino-2-((tert-butoxycarbonyl)amino)butanoic acid from BOC-L-glutamine: to a mixed solution of (S)-5-amino-2-(tert-butoxycarbonylamino)-5-oxopentanoic acid (2 g, 8.1 mmol) in DMF and water (1:1, v/v, 18 ml) was added pyridine (1.3 ml, 16.2 mmol). The reaction mixture was stirred at room temperature for 5-10 min. Subsequently, iodobenzene diacetate (3.92 g, 12.1 mmol) was added and the reaction was continued with stirring for 4 hours. After completion of the reaction, deionized water (100 ml) was added to the reaction mixture and extracted with ethyl acetate (3 x 100 ml). The organic phases were combined and washed sequentially with deionized water (100 ml) and saturated saline (100 ml), dried over anhydrous sodium sulfate and concentrated under reduced pressure to obtain the crude product. The crude product was purified by ether milling and after evaporation of the product grades, 1.1 g (62% yield) of the target compound was obtained as a brown solid. LC-MS analysis showed m/z = 219.1 (M + H).

References

[1] Synthetic Communications, 2004, vol. 34, # 6, p. 1049 - 1056
[2] Journal of Medicinal Chemistry, 2009, vol. 52, # 15, p. 4650 - 4656
[3] Bioorganic and Medicinal Chemistry, 1999, vol. 7, # 1, p. 161 - 175
[4] Patent: WO2014/151472, 2014, A1. Location in patent: Paragraph 00340-00341
[5] Patent: WO2016/40315, 2016, A1. Location in patent: Paragraph 00383; 00384

Boc-L-2,4-diaminobutyric acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-L-2,4-diaminobutyric acid Suppliers

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View Lastest Price from Boc-L-2,4-diaminobutyric acid manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-Dab-OH 25691-37-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2023-09-18

Career Henan Chemical Co

Product: Boc-L-2,4-diaminobutyric acid 25691-37-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,100kg
Release date: 2019-07-04

25691-37-6, Boc-L-2,4-diaminobutyric acidRelated Search:

DL-2-Aminobutyric acid DL-3-Aminobutyric acid 4-Aminobutyric acid tert-Butyl carbazate L(+)-2-Aminobutyric acid D-2-Aminobutyric acid Boc-D-2,4-diaminobutyric acid N-tert-Butoxycarbonyl-L-glutamic acid gamma-tert-butyl ester BOC-OIC-OH Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate BOC-ASP-OH BOC-L-Asparagine Boc-N-beta-Trityl-L-asparagine N-Boc-cis-4-Fmoc-Amino-L-proline FMOC-DAB(BOC)-OH Z-DBU(BOC)-OH N-GAMMA-BOC-L-2,4-DIAMINOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE r-Amino Butryric Acid

2-amino-4-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]butanoic acid

BOC-ALPHA,GAMMA-DIAMINOBUTYRIC ACID

BOC-L-DAB-OH

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N-ALPHA-T-BUTOXYCARBONYL-L-ALPHA, GAMMA-DIAMINOBUTYRIC ACID

N-ALPHA-T-BUTYLOXYCARBONYL-L-2,4-DIAMINOBUTYRIC ACID

N-ALPHA-TERT-BUTYLOXYCARBONYL-L-2,4-DIAMINOBUTYRIC ACID

N-ALPHA-BOC-L-2,4-DIAMINOBUTYRIC ACID

N2-BOC-(S)-2,4-DIAMINO-BUTANOIC ACID

N?Boc-L-2,4-diaminobutyric acid

Na-Boc-L-2,4-diaminobutyric acid

BOC-DAB

(S)-4-AMino-2-(tert-butoxycarbonylaMino)butyric Acid

(2S)-4-aMino-2-[(tert-butoxycarbonyl)aMino]butanoic acid

(S)-4-AMino-2-(Boc-aMino)butyric acid, 97%

Boc-Dab-OH(Na-Boc-2,4-DiaMinobutyric acid)

(S)-4-Amino-2-(tert-butoxycarbonylamino)butyric acid, 98.0%

N-alpha-Ac-N&gamma

Butanoic acid,4-aMino-2-[[(1,1-diMethylethoxy)carbonyl]aMino]-, (2S)-

(S)-4-AMino-2-((tert-butoxycarbonyl)aMino)butanoic acid

(S)-4-Amino-2-(Boc-amino)butanoic acid

Nα-Boc-L-2,4-diaminobutyric acid99%

(S)-4-Amino-2-(Boc-amino)butyric Acid (S)-Nα-Boc-2,4-diaminobutyric Acid Boc-Dab-OH

(2S)-4-Amino-2-[[(1,1-dimethylethoxy)carbonyl]amino]butanoic acid

(Tert-Butoxy)Carbonyl Dab-OH

(2S)-4-AMINO-2-[(2-METHYLPROPAN-2-YL)OXYCARBONYLAMINO]BUTANOIC ACID

N-Boc-(S)-2,4-diamino-butanoic acid

(S)-4-Amino-2-(tert-butoxycarbonylamino)butyric Acid &gt

(2S)-4-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoicaci

(S)-Nalpha-Boc-2,4-diaminobutyric Acid

Boc-L-2,4-diaminobutyric acid USP/EP/BP

Nα-Boc-L-2,4-diaminobutyric acid

Boc-L-2,4-Dlaminobutyrlc Acid

(S)-4-amino-2-((tertbutyloxyoxo)amino)butanoic acid

(2S)-4-Amino-2-[N-BOC-amino]butanoic acid

25691-37-6

pharmacetical

Amino Acids & Deriv.

CHIRAL CHEMICALS