N-(2-Oxoethyl)phthalimide

Product Name: N-(2-Oxoethyl)phthalimide
CAS No.: 2913-97-5
Chemical Name: N-(2-Oxoethyl)phthalimide
Synonyms: 2-(1,3-DIOXOISOINDOLIN-2-YL)ACETALDEHYDE;NSC 30242;PHTHALIMIDOACETALDEHYDE;N-(2-Formyl)phthalimide;Rucaparib Intermediate 1;Phthalylglycine aldehyde;N-(2-OXOETHYL)PHTHALIMIDE;2-PHTHALIMIDOACETALDEHYDE;2-Phthalimidylacetaldehyde;Phthalimidoacetaldehyde>
CBNumber: CB2496913
Molecular Formula: C10H7NO3
Formula Weight: 189.17
MOL File: 2913-97-5.mol

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N-(2-Oxoethyl)phthalimide Property

Melting point:: 116-118°C
Boiling point:: 324.3±25.0 °C(Predicted)
Density: 1.376±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: Chloroform (Slightly, Heated, Sonicated), Ethyl Acetate (Slightly)
form: Solid
pka: -2.45±0.20(Predicted)
color: White to Pale Yellow
InChI: InChI=1S/C10H7NO3/c12-6-5-11-9(13)7-3-1-2-4-8(7)10(11)14/h1-4,6H,5H2
InChIKey: LMRDBJZQDUVCQH-UHFFFAOYSA-N
SMILES: C1(=O)C2=C(C=CC=C2)C(=O)N1CC=O

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Safety

RTECS: TI5125000
HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: P2010
Product name: Phthalimidoacetaldehyde
Purity: >98.0%(N)
Packaging: 1g
Price: $65
Updated: 2025/07/31

TCI Chemical

Product number: P2010
Product name: Phthalimidoacetaldehyde
Purity: >98.0%(N)
Packaging: 5g
Price: $211
Updated: 2025/07/31

TRC

Product number: P384500
Product name: Phthalimidoacetaldehyde
Packaging: 5g
Price: $950
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0014840
Product name: PHTHALIMIDOACETALDEHYDE
Purity: 95.00%
Packaging: 1G
Price: $983.52
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0014840
Product name: PHTHALIMIDOACETALDEHYDE
Purity: 95.00%
Packaging: 2.5G
Price: $1473.14
Updated: 2021/12/16

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N-(2-Oxoethyl)phthalimide Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Phthalimidoacetaldehyde (cas# 2913-97-5) is a compound useful in organic synthesis.

Synthesis

78902-09-7

2913-97-5

Example 5: Preparation of N-2-[4-(4-bromo-2-fluorophenylamino)-7-(1-methylpiperidin-4-ylmethoxy)-quinazolin-6-ylamino]-ethyl-propenamide Step 5-1: Synthesis of 1,3-dioxo-1,3-dihydroisoindol-2-yl acetaldehyde Phthalimidoacetaldehyde diethyl acetal (10 g, 0.0379 mol) was dissolved in 100 mL of aqueous 1N HCl, refluxed and stirred for 1 hour. Upon completion of the reaction, the reaction solution was extracted with 200 mL of dichloromethane, followed by washing the organic layer with 100 mL of saturated saline. The solvent was removed by distillation under reduced pressure to give N-(2-acetaldehyde-based) phthalimide 7.16 g (yield: 99%). 1H NMR (CDCl3) δ: 9.66 (s, 1H), 7.90-7.84 (m, 2H), 7.78-7.73 (m, 2H), 4.56 (s, 2H).

References

[1] Tetrahedron, 2002, vol. 58, # 9, p. 1719 - 1737
[2] Tetrahedron, 2008, vol. 64, # 28, p. 6794 - 6800
[3] Patent: WO2007/55513, 2007, A1. Location in patent: Page/Page column 29
[4] Angewandte Chemie - International Edition, 2015, vol. 54, # 33, p. 9668 - 9672
[5] Angew. Chem., 2015, vol. 127, # 33, p. 9804 - 9808,5

N-(2-Oxoethyl)phthalimide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(2-Oxoethyl)phthalimide Suppliers

Canada 1 China 193 Germany 4 India 4 Japan 1 Switzerland 1 United States 18 Global 222

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View Lastest Price from N-(2-Oxoethyl)phthalimide manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: N-(2-Oxoethyl)phthalimide 2913-97-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

Shanghai UCHEM Inc.

Product: N-(2-Oxoethyl)phthalimide 2913-97-5
Price: US $349.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 25kg
Release date: 2023-11-16

Zhuozhou Wenxi import and Export Co., Ltd

Product: N-(2-oxoethyl)phthalimide 2913-97-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

2913-97-5, N-(2-Oxoethyl)phthalimideRelated Search:

Succinimide 4-Aminophthalimide Maleimide O-Phthalimide 3-Nitrophthalimide 4-Nitrophthalimide Potassium phthalimide Acetaldehyde Bismaleimide N-Hydroxyphthalimide N-Methylphthalimide N-(2-Hydroxy-2-oxoethyl)phthalimide DIALIFOS N-(2-Chloro-2-oxoethyl)phthalimide N-PHTHALOYLGLYCINEAMIDE PHT-LEU-OH 2-PHTHALIMIDOPROPIONIC ACID 2-PHTHALIMIDOGLUTARANILIC ACID

N-phthalimidyl-2-aminoacetaldehyde

(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetaldehyde

[(1,3-Dioxo-1,3-dihydro-2H-isoindole)-2-yl]acetaldehyde

1,3-Dihydro-1,3-dioxo-2H-isoindole-2-acetaldehyde

2-Phthalimidylacetaldehyde

2-(1,3-Dioxoisoindol-2-yl)ethanal

2-(1,3-Dioxo-1,3-dihydroisoindol-2-yl)acetaldehyde

NSC 30242

2-(1,3-diketoisoindolin-2-yl)acetaldehyde

2-(1,3-dioxoisoindol-2-yl)acetaldehyde

dimethyl acetal of phthalimidoacetaldehyde

(1,3-Dioxo-1,3-dihydroisoindol-2-yl)

2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)acetaldehyde

2H-Isoindole-2-acetaldehyde,1,3-dihydro-1,3-dioxo-

2-(1,3-Dioxo-2-isoindolinyl)acetaldehyde

Rucaparib Intermediate 1

(1,3-DIOXO-1,3-DIHYDROISOINDOL-2-YL)ACETALDEHYDE

1,3-DIOXO-2-ISOINDOLINEACETALDEHYDE

2-(1,3-DIOXOISOINDOLIN-2-YL)ACETALDEHYDE

N-(2-OXOETHYL)PHTHALIMIDE

N-(FORMYLMETHYL)PHTHALIMIDE

n-(formylmethyl)-phthalimid

PHTHALIMIDOACETALDEHYDE

2-PHTHALIMIDOACETALDEHYDE

N - (2-acetaldehyde) phthalimide

Phthalimidoacetaldehyde&gt

Phthalylglycine aldehyde

PHTHALIMIDOACETALDEHYDE 98%

N-(2-Formyl)phthalimide

1,3-Dihydro-1,3-dioxo-2H-isoindol-2-acetaldehyde

2913-97-5

Aromatics Compounds

Aromatics

Cross Linking Reagents

Heterocycles

Miscellaneous Reagents

2913-97-5