CYCLIC-PIFITHRIN-ALPHA

Product Name: CYCLIC-PIFITHRIN-ALPHA
CAS No.: 60477-34-1
Chemical Name: CYCLIC-PIFITHRIN-ALPHA
Synonyms: Pifithrin-2;Pifithrin-alpha (cyclic) . HBr;Pifithrin-β (QB-102 and Cyclic-Pifithrin-α);Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem;2-(p-Tolyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole;5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole;Imidazo[2,1-b]benzothiazole, 5,6,7,8-tetrahydro-2-(4-methylphenyl)-
CBNumber: CB2504209
Molecular Formula: C16H16N2S
Formula Weight: 268.38
MOL File: 60477-34-1.mol

More

Less

CYCLIC-PIFITHRIN-ALPHA Property

Melting point:: 266.4-267.3 °C(lit.)
Density: 1.30±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO: 20 mg/mL
form: White solid
pka: 6.75±0.20(Predicted)

More

Less

Safety

WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

ApexBio Technology

Product number: B4813
Product name: Pifithrin-β
Packaging: 5mg
Price: $87
Updated: 2021/12/16

ApexBio Technology

Product number: B4813
Product name: Pifithrin-β
Packaging: 10mg
Price: $148
Updated: 2021/12/16

Axon Medchem

Product number: Axon3051
Product name: Pifithrin-β-PFT-β|Z-2-035II
Purity: 99%
Packaging: 2x10mg
Price: $165
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0017104
Product name: PIFITHRIN-B
Purity: 95.00%
Packaging: 5MG
Price: $497.16
Updated: 2021/12/16

ApexBio Technology

Product number: B4813
Product name: Pifithrin-β
Packaging: 50mg
Price: $607
Updated: 2021/12/16

More

Less

CYCLIC-PIFITHRIN-ALPHA Chemical Properties,Usage,Production

Definition

ChEBI: 2-(4-methylphenyl)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]benzothiazole is a member of imidazoles.

General Description

A cell-permeable and very stable analog of Pifithrin-α (Cat. No. 506132), with similar biological function, but with reduced cytotoxicity. A chemical inhibitor of p53. Reversibly inhibits p53-dependent transactivation of p53-responsive genes; also reversibly blocks p53-mediated apoptosis. Acts as a P-gp modulator by changing relative substrate specificity of the transporter. This compound has been reported to be a potent STAT6 transcriptional inhibitor.

Biochem/physiol Actions

Cell permeable: yes

CYCLIC-PIFITHRIN-ALPHA Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

CYCLIC-PIFITHRIN-ALPHA Suppliers

China 19 Switzerland 1 United States 8 Global 28

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 4602
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Angel Pharmatech, Ltd.

Tel: 17317130613
Fax: QQ3358272972
Email: 3358272972@qq.com
Country: China
ProdList: 3251
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

Hangzhou Synstar pharmaceutical Technology CO.,Ltd

Tel: 0571-85361029
Fax: 0571-85361029
Email: synstar518@163.com
Country: China
ProdList: 1990
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30240
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
Advantage: 58

Shanghai Botuo Biotechnology Co., LTD

Tel: 16621358918
Fax: QQ:402135374
Email: botuopharma888@163.com
Country: China
ProdList: 9208
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

Changzhou Furuisi Biotechnology Co., Ltd

Tel: 0519-85524369
Email: 3477467573@qq.com
Country: China
ProdList: 8617
Advantage: 58

InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6753
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55013243 15324716602
Email: 2853979810@qq.com
Country: China
ProdList: 10018
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: cindy.huang@synzest.com
Country: China
ProdList: 12005
Advantage: 58

ATK CHEMICAL COMPANY LIMITED

Tel: +undefined-21-51877795
Fax: +86 21 5161 9052/ 5187 7796
Email: ivan@atkchemical.com
Country: China
ProdList: 32957
Advantage: 60

60477-34-1, CYCLIC-PIFITHRIN-ALPHARelated Search:

Pifithrin-α (PFTα) SB 220025 PRIMA-1 PD 169316 FHPI HCL CP 31398 SB 239063 SB 202190 1H-INDOLE-5-CARBOXAMIDE, 97% JX401

Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem

Pifithrin-alpha (cyclic) . HBr

5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole

Pifithrin-2

Imidazo[2,1-b]benzothiazole, 5,6,7,8-tetrahydro-2-(4-methylphenyl)-

Pifithrin-β (QB-102 and Cyclic-Pifithrin-α)

2-(p-Tolyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole

60477-34-1