ChemicalBook > CAS DataBase List > S-NITROSOGLUTATHIONE

S-NITROSOGLUTATHIONE

Product Name
S-NITROSOGLUTATHIONE
CAS No.
57564-91-7
Chemical Name
S-NITROSOGLUTATHIONE
Synonyms
SNOG;GSNO;GNSO;RVC 588;GSNO, SNOG;RVC 588 (peptide);nitrosoglutathione;S-Nitrosoglutatione;S-NITROSOGLUTATHIONE;S-Nitrosylglutathione
CBNumber
CB2664125
Molecular Formula
C10H16N4O7S
Formula Weight
336.32
MOL File
57564-91-7.mol
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S-NITROSOGLUTATHIONE Property

Melting point:
>170°C (dec.)
Density 
1.68
refractive index 
1.6000 (estimate)
storage temp. 
-20°C
solubility 
DMSO (Slightly), Water (Slightly)
form 
Pink solid
pka
2.21±0.10(Predicted)
color 
Off-White to Pink
Water Solubility 
Soluble to 100 mM in water
Stability:
Hygroscopic
CAS DataBase Reference
57564-91-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
MC0558000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
487920
Product name
S-Nitrosoglutathione
Purity
A utility carrier of nitric oxide.
Packaging
10mg
Price
$96.7
Updated
2024/03/01
Sigma-Aldrich
Product number
487920
Product name
S-Nitrosoglutathione
Purity
A utility carrier of nitric oxide.
Packaging
1set
Price
$280
Updated
2024/03/01
Cayman Chemical
Product number
82240
Product name
S-Nitroso-L-glutathione
Purity
≥98%
Packaging
5mg
Price
$26
Updated
2024/03/01
Cayman Chemical
Product number
82240
Product name
S-Nitroso-L-glutathione
Purity
≥98%
Packaging
10mg
Price
$49
Updated
2024/03/01
Sigma-Aldrich
Product number
N4148
Product name
S-Nitrosoglutathione
Purity
≥97%
Packaging
25mg
Price
$367
Updated
2024/03/01
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S-NITROSOGLUTATHIONE Chemical Properties,Usage,Production

Description

S-Nitroso-L-glutathione is an S-nitrosothiol NO donor based on naturally-occurring glutathione. It is a potent smooth muscle relaxant and inhibitor of platelet aggregation. Its stability in solution varies from seconds to hours depending on temperature, buffer composition, and metal content.

Chemical Properties

Pink Powder

Uses

A carrier of nitric oxide, relaxing smooth muscle and inhibiting platelet activation

Uses

S-Nitrosoglutathione (GSNO) has been used:

  • as a standard in reversed phase chromatography coupled to chemical vapour generation and atomic fluorescence detector (RPC-CVGAFS) and reversed phase chromatography fluorimetric (RPC-FD).
  • as a standard in spectrophotometric and high-performance liquid chromatography (HPLC) assay.

Definition

ChEBI: S-nitrosoglutathione is a glutathione derivative that is glutathione in which the hydrogen attached to the sulfur has been replaced by a nitroso group. It has a role as a platelet aggregation inhibitor, a bronchodilator agent, a nitric oxide donor and a signalling molecule. It is a glutathione derivative and a nitrosothio compound. It is a conjugate acid of a S-nitrosoglutathione(2-).

General Description

A utility carrier of nitric oxide. Breaks down at physiological pH to produce nitric oxide. Causes smooth muscle relaxation and inhibits platelet aggregation. Induces apoptosis in mouse thymocytes. Note: 1 set = 5 x 2.5 mg.

Biological Activity

A carrier of NO, relaxing smooth muscle and inhibiting platelet aggregation.

Biochem/physiol Actions

Product does not compete with ATP.

storage

Desiccate at -20°C

S-NITROSOGLUTATHIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from S-NITROSOGLUTATHIONE manufacturers

Career Henan Chemical Co
Product
S-NITROSOGLUTATHIONE 57564-91-7
Price
US $1.00/KG
Min. Order
1KG
Purity
98%-99.9%
Supply Ability
100kg
Release date
2020-01-10

57564-91-7, S-NITROSOGLUTATHIONERelated Search:


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  • (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-3-nitrososulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
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  • GSNO
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  • GSNO, SNOG
  • S-NITROSO-L-GLUTATHIONE, 97+%
  • Glycine, L-γ-glutamyl-S-nitroso-L-cysteinyl-
  • S-Nitrosoglutathione, ≥97%
  • (2S)-2-amino-5-[[(1R)-2-(carboxymethylamino)-1-(nitrososulfanylmethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid
  • S-Nitrosoglutatione
  • Talabostat Impurity 27
  • S-Nitrosoglutathione (SNOG), NO donor
  • 57564-91-7
  • C10H15N4O7S
  • C10H16N4O7S
  • Application Index
  • Biochemicals and Reagents
  • BioChemical
  • Cell Signaling Enzymes
  • Enzymes, Inhibitors, and Substrates
  • NO Donors
  • Nitric Oxide Metabolism
  • Peptides
  • Sulfur & Selenium Compounds
  • Signalling
  • Nitric Oxide Reagents
  • Nitric Oxide