SPERMINE NONOATE

Product Name: SPERMINE NONOATE
CAS No.: 136587-13-8
Chemical Name: SPERMINE NONOATE
Synonyms: NOC-22;SPER/NO;SPERMINE NONOATE;Spermine NONOate,97%;SpermineNONOate,SPER/NO;Spermine Bis(NO) Adduct;SPERMINE/NITRIC OXIDE COMPLEX;SPERMINE BIS (NITRIC OXIDE) ADDUCT;SPERMINE/NITRIC OXIDE COMPLEX (SPER/NO);Spermine-Nitric oxide complex hydrate
CBNumber: CB5128354
Molecular Formula: C10H26N6O2
Formula Weight: 262.35
MOL File: 136587-13-8.mol

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SPERMINE NONOATE Property

Melting point:: 105-107°C
Boiling point:: 405.6°C (rough estimate)
Density: 1.0879 (rough estimate)
refractive index: 1.7000 (estimate)
storage temp.: -20°C
solubility: methanol: ≥1mg/mL
form: White solid
pka: 5.47±0.69(Predicted)
color: white
Stability:: Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Buffer solutions are not stable and must be prepared immediately before use.

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Safety

Safety Statements: 22-24/25

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S150
Product name: Spermine–Nitric oxide complex
Purity: source of nitric oxide
Packaging: 25mg
Price: $197
Updated: 2021/12/16

Cayman Chemical

Product number: 82150
Product name: Spermine NONOate
Purity: ≥98%
Packaging: 10mg
Price: $39
Updated: 2024/03/01

Cayman Chemical

Product number: 82150
Product name: Spermine NONOate
Purity: ≥98%
Packaging: 25mg
Price: $92
Updated: 2024/03/01

Cayman Chemical

Product number: 82150
Product name: Spermine NONOate
Purity: ≥98%
Packaging: 50mg
Price: $172
Updated: 2024/03/01

Cayman Chemical

Product number: 82150
Product name: Spermine NONOate
Purity: ≥98%
Packaging: 100mg
Price: $302
Updated: 2024/03/01

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SPERMINE NONOATE Chemical Properties,Usage,Production

Description

Spermine NONOate (136587-13-8) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner.? ? The half-life of Spermine NONOate in 0.1 M phosphate buffer at pH 7.4 is 39 min at 37 °C, or 230 min at room temperature.1? ? Dissociation is essentially instantaneous at a pH of 5.0.

Chemical Properties

Off-White Solid

Uses

A reagent which releases Nitric Oxide into aqueous solutions at controlled rates for in vitro studies.

General Description

Complex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t_?) of NO release = 230 min (PBS, pH 7.4, 22°C).

Biological Activity

A stable complex of nitric oxide and spermine used to generate a controlled release of nitric oxide in solution (EC 50 = 6.2 μ M for relaxation of rabbit aorta, and t=39 min at 37℃, pH 7.4, aqueous solution).

Biochem/physiol Actions

Product does not compete with ATP.

References

1) Keefer et al. (1996), “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms; Methods Enzymol., 268 281

SPERMINE NONOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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SPERMINE NONOATE Suppliers

Canada 1 China 37 Germany 1 India 1 Japan 1 Switzerland 3 United Kingdom 5 United States 21 Global 70

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4674
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52693
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57423
Advantage: 58

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View Lastest Price from SPERMINE NONOATE manufacturers

Guangzhou Sunton Biotechnology Co., Ltd.

Product: Spermine NONOate 136587-13-8
Price: US $48.00-40.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200tons
Release date: 2021-04-15

136587-13-8, SPERMINE NONOATERelated Search:

Sodium nitroprusside dihydrate NOC-18 DPTA NONOATE NOC-7 MAHMA NONOATE 4-(N-CYANOMETHYL-N-NITROSO)AMINOMORPHOLINE S-NITROSOGLUTATHIONE NOC-5 BETA-GAL-NONOATE GEA 3162 NOR-3 Ethylenediamine NITRIC OXIDE Dipentene SPERMINE DIHYDRATE SPERMINE NONOATE PAPA NONOATE DEA NONOATE

(Z)-1-[N-[3-AMINOPROPYL]-N-[4-(3-AMINOPROPYL-AMMONIO)BUTYL]-AMINO]-DIAZEN-1-IUM-1,2-DIOLATE

(Z)-1-[N-(3-AMMONIOPROPYL)-N-[4-(3-AMINOPROPYLAMMONIO) BUTYL]-AMINO]DIAZEN-1-IUM-1,2-DIOLATE

SPERMINE BIS (NITRIC OXIDE) ADDUCT

SPERMINE/NITRIC OXIDE COMPLEX

SPERMINE NONOATE

SPER/NO

NOC-22

N-[4-[1-(3-AMINOPROPYL)-2-HYDROXY-2-NITROSOHYDRAZINO]BUTYL]-1,3-PROPANEDIAMINE

N-(2-AMINOETHYL)-N-(2-HYDROXY-2-NITROSOHYDRAZINO)-1,2-ETHYLENEDIAMINE

N-(2-AMINOETHYL)-N-(2-HYDROXY-3-NITROSOHYDRAZINO)-1,2-ETHYLENEDIAMINE

SPERMINE/NITRIC OXIDE COMPLEX (SPER/NO)

SpermineNONOate,SPER/NO

N1-[4-[1-(3-Aminopropyl)-2-hydroxy-2-nitrosohydrazinyl]butyl]-1,3-propanediamine

Spermine Bis(NO) Adduct

SPER/NO, Spermine NONOate, N-[4-[1-(3-Aminopropyl)-2-hydroxy-2-nitrosohydrazino]butyl]-1,3-propanediamine

Spermine-Nitric oxide complex hydrate

Spermine NONOate,97%

N'-(3-aMinopropyl)-N'-(4-((3-aMinopropyl)aMino)butyl)-N-hydroxynitrous hydrazide hydrate

Spermine NONOate - CAS 136587-13-8 - Calbiochem

N'-(3-Aminopropyl)-N'-(4-((3-aminopropyl)amino)butyl)-N-hydroxynitrous hydrazide

1,3-Propanediamine, N1-[4-[1-(3-aminopropyl)-2-hydroxy-2-nitrosohydrazinyl]butyl]-

136587-13-8

C10H26N6O2H2O

C10H26N6O2

Application Index

Cell Signaling Enzymes

Biochemicals and Reagents

BioChemical

NO Donors

Nitric Oxide Metabolism

Enzymes, Inhibitors, and Substrates

Nitric Oxide Reagents

Amines