ChemicalBook > CAS DataBase List > SPERMINE NONOATE
SPERMINE NONOATE
- Product Name
- SPERMINE NONOATE
- CAS No.
- 136587-13-8
- Chemical Name
- SPERMINE NONOATE
- Synonyms
- NOC-22;SPER/NO;SPERMINE NONOATE;Spermine NONOate,97%;SpermineNONOate,SPER/NO;Spermine Bis(NO) Adduct;SPERMINE/NITRIC OXIDE COMPLEX;SPERMINE BIS (NITRIC OXIDE) ADDUCT;SPERMINE/NITRIC OXIDE COMPLEX (SPER/NO);Spermine-Nitric oxide complex hydrate
- CBNumber
- CB5128354
- Molecular Formula
- C10H26N6O2
- Formula Weight
- 262.35
- MOL File
- 136587-13-8.mol
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SPERMINE NONOATE Property
- Melting point:
- 105-107°C
- Boiling point:
- 405.6°C (rough estimate)
- Density
- 1.0879 (rough estimate)
- refractive index
- 1.7000 (estimate)
- storage temp.
- -20°C
- solubility
- methanol: ≥1mg/mL
- form
- White solid
- pka
- 5.47±0.69(Predicted)
- color
- white
- Stability:
- Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Buffer solutions are not stable and must be prepared immediately before use.
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Safety
- Safety Statements
- 22-24/25
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- S150
- Product name
- Spermine–Nitric oxide complex
- Purity
- source of nitric oxide
- Packaging
- 25mg
- Price
- $197
- Updated
- 2021/12/16
Cayman Chemical
- Product number
- 82150
- Product name
- Spermine NONOate
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $39
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 82150
- Product name
- Spermine NONOate
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $92
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 82150
- Product name
- Spermine NONOate
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $172
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 82150
- Product name
- Spermine NONOate
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $302
- Updated
- 2024/03/01
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SPERMINE NONOATE Chemical Properties,Usage,Production
Description
Spermine NONOate (136587-13-8) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner.? ? The half-life of Spermine NONOate in 0.1 M phosphate buffer at pH 7.4 is 39 min at 37 °C, or 230 min at room temperature.1? ? Dissociation is essentially instantaneous at a pH of 5.0.
Chemical Properties
Off-White Solid
Uses
A reagent which releases Nitric Oxide into aqueous solutions at controlled rates for in vitro studies.
General Description
Complex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t?) of NO release = 230 min (PBS, pH 7.4, 22°C).
Biological Activity
A stable complex of nitric oxide and spermine used to generate a controlled release of nitric oxide in solution (EC 50 = 6.2 μ M for relaxation of rabbit aorta, and t=39 min at 37℃, pH 7.4, aqueous solution).
Biochem/physiol Actions
Product does not compete with ATP.
References
1) Keefer et al. (1996), “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms; Methods Enzymol., 268 281
SPERMINE NONOATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from SPERMINE NONOATE manufacturers
Guangzhou Sunton Biotechnology Co., Ltd.
- Product
- Spermine NONOate 136587-13-8
- Price
- US $48.00-40.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200tons
- Release date
- 2021-04-15
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