PAPA NONOATE

Product Name: PAPA NONOATE
CAS No.: 146672-58-4
Chemical Name: PAPA NONOATE
Synonyms: NOC-15;PAPA/NO;PAPA NONATE;PAPA NONOATE;NOC-15 NONOATE;PROPYLAMINE PROPYLAMINE NONOATE;PAPA NONOate, Nitric oxide (NO) donor;3-[[nitroso(oxido)amino]-propylamino]propylazanium;1-HYDROXY-2-OXO-3-(3-AMINOPROPYL)-3-PROPYL-1-TRIAZENE;3-(2-hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine
CBNumber: CB7360963
Molecular Formula: C6H16N4O2
Formula Weight: 176.22
MOL File: 146672-58-4.mol

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PAPA NONOATE Property

Boiling point:: 277.2±42.0 °C(Predicted)
Density: 1.20±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in Water or Ethanol.
form: White to off-white solid.
pka: 5.55±0.69(Predicted)
color: Off-white
Stability:: Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Solutions are not stable and must be prepared immediately before use.

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Safety

Hazard Codes: Xn
Risk Statements: 22

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 82140
Product name: PAPA NONOate
Purity: ≥98%
Packaging: 25mg
Price: $47
Updated: 2024/03/01

Cayman Chemical

Product number: 82140
Product name: PAPA NONOate
Purity: ≥98%
Packaging: 50mg
Price: $87
Updated: 2024/03/01

Cayman Chemical

Product number: 82140
Product name: PAPA NONOate
Purity: ≥98%
Packaging: 100mg
Price: $163
Updated: 2024/03/01

Cayman Chemical

Product number: 82140
Product name: PAPA NONOate
Purity: ≥98%
Packaging: 500mg
Price: $574
Updated: 2023/06/20

AK Scientific

Product number: 1980AH
Product name: Papanonoate
Packaging: 100mg
Price: $279
Updated: 2021/12/16

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PAPA NONOATE Chemical Properties,Usage,Production

Description

PAPA NONOate (146672-58-4) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner. The half-life of PAPA NONOate in 0.1 M phosphate buffer at pH 7.4 is 15 minutes at 37°C, or 77 minutes at room temperature.1?Dissociation is essentially instantaneous at a pH of 5.0.

Uses

PAPA NONOate is an NO donor which suppresses the caspase apoptotic cascade.

Definition

ChEBI: PAPA NONOate is an alkylamine.

in vivo

PAPA NONOate (100 μM in phosphate buffer) increases the rate of wound healing in rats with diabetes and wound^[2].

Animal Model:	Anesthetized male Sprague-Dawley rats with streptozotocin-induced diabetes and full thickness dermal wound^[2]
Dosage:	100 μM
Administration:	Wounds received 100 μM PAPA NONOate in phosphate buffer
Result:	Increased the wound healing rate in test group.

References

[1] L K KEEFER. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms.[J]. Methods in enzymology, 1996, 268: 281-293. DOI:10.1016/s0076-6879(96)68030-6

PAPA NONOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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PAPA NONOATE Suppliers

China 47 Germany 1 Japan 1 Switzerland 3 United Kingdom 3 United States 14 Global 69

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

146672-58-4, PAPA NONOATERelated Search:

Sodium nitroprusside dihydrate NOC-18 NOC-7 MAHMA NONOATE 4-(N-CYANOMETHYL-N-NITROSO)AMINOMORPHOLINE S-NITROSOGLUTATHIONE NOC-5 DEA NONOate GEA 5024 Vorinostat NOC-12 V-PYRRO/NO GEA 3162 BETA-GAL-NONOATE NOR-3 DPTA NONOATE SPERMINE NONOATE PAPA NONOATE

3-(2-HYDROXY-2-NITROSO-1-PROPYLHYDRAZINO)-1-PROPANAMINE NONOATE

1-HYDROXY-2-OXO-3-(3-AMINOPROPYL)-3-PROPYL-1-TRIAZENE

(Z)-1-[N-(3-AMMONIOPROPYL)-N-(N-PROPYL)AMINO]DIAZEN-1-IUM-1,2-DIOLATE

(Z)-1-[N-(3-AMINOPROPYL)-N-)B-PROPYL)AMINO]DIAZIN-1-IUM-1,2-DIOLATE

PROPYLAMINE PROPYLAMINE NONOATE

PAPA/NO

PAPA NONOATE

NOC-15

NOC-15 NONOATE

PAPA NONATE

3-(2-hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine

3-(2-Hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine, NOC-15

3-[[nitroso(oxido)amino]-propylamino]propylazanium

1-Propanamine, 3-(2-hydroxy-2-nitroso-1-propylhydrazinyl)-

PAPA NONOate, Nitric oxide (NO) donor

146672-58-4

C6H16N4O2

NO Donors

Enzymes, Inhibitors, and Substrates

Nitric Oxide Metabolism

BioChemical

Biochemicals and Reagents

Cell Signaling Enzymes

Application Index