ChemicalBook > CAS DataBase List > PAPA NONOATE

PAPA NONOATE

Product Name
PAPA NONOATE
CAS No.
146672-58-4
Chemical Name
PAPA NONOATE
Synonyms
NOC-15;PAPA/NO;PAPA NONATE;PAPA NONOATE;NOC-15 NONOATE;PROPYLAMINE PROPYLAMINE NONOATE;PAPA NONOate, Nitric oxide (NO) donor;3-[[nitroso(oxido)amino]-propylamino]propylazanium;1-HYDROXY-2-OXO-3-(3-AMINOPROPYL)-3-PROPYL-1-TRIAZENE;3-(2-hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine
CBNumber
CB7360963
Molecular Formula
C6H16N4O2
Formula Weight
176.22
MOL File
146672-58-4.mol
More
Less

PAPA NONOATE Property

Boiling point:
277.2±42.0 °C(Predicted)
Density 
1.20±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in Water or Ethanol.
form 
White to off-white solid.
pka
5.55±0.69(Predicted)
color 
Off-white
Stability:
Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Solutions are not stable and must be prepared immediately before use.
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
82140
Product name
PAPA NONOate
Purity
≥98%
Packaging
25mg
Price
$47
Updated
2024/03/01
Cayman Chemical
Product number
82140
Product name
PAPA NONOate
Purity
≥98%
Packaging
50mg
Price
$87
Updated
2024/03/01
Cayman Chemical
Product number
82140
Product name
PAPA NONOate
Purity
≥98%
Packaging
100mg
Price
$163
Updated
2024/03/01
Cayman Chemical
Product number
82140
Product name
PAPA NONOate
Purity
≥98%
Packaging
500mg
Price
$574
Updated
2023/06/20
AK Scientific
Product number
1980AH
Product name
Papanonoate
Packaging
100mg
Price
$279
Updated
2021/12/16
More
Less

PAPA NONOATE Chemical Properties,Usage,Production

Description

PAPA NONOate (146672-58-4) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner. The half-life of PAPA NONOate in 0.1 M phosphate buffer at pH 7.4 is 15 minutes at 37°C, or 77 minutes at room temperature.1?Dissociation is essentially instantaneous at a pH of 5.0.

Uses

PAPA NONOate is an NO donor which suppresses the caspase apoptotic cascade.

Definition

ChEBI: PAPA NONOate is an alkylamine.

in vivo

PAPA NONOate (100 μM in phosphate buffer) increases the rate of wound healing in rats with diabetes and wound[2].

Animal Model:Anesthetized male Sprague-Dawley rats with streptozotocin-induced diabetes and full thickness dermal wound[2]
Dosage:100 μM
Administration:Wounds received 100 μM PAPA NONOate in phosphate buffer
Result:Increased the wound healing rate in test group.

References

[1] L K KEEFER. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms.[J]. Methods in enzymology, 1996, 268: 281-293. DOI:10.1016/s0076-6879(96)68030-6

PAPA NONOATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

PAPA NONOATE Suppliers

China 47 Germany 1 Japan 1 Switzerland 3 United Kingdom 3 United States 14 Global 69
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15873
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Suzhou Zhixin Biotechnology Co., Ltd.
Tel
0512-65118909 18100677375
Email
sales@szzxbio.com
Country
China
ProdList
2993
Advantage
58
Chengdu Peter-like Biotechnology Co., Ltd.
Tel
028-81700200 13308200041
Email
2851167782@qq.com
Country
China
ProdList
11146
Advantage
58
Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
6710
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58
Enzo Biochem Inc
Tel
Enzo Biochem Inc. 13797054060
Email
Enzoname@qq.com
Country
China
ProdList
6174
Advantage
58
Aikon International Limited
Tel
025-58859352 18651614124
Email
2881516338@qq.com
Country
China
ProdList
10000
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
Shanghai Shitang Industrial Co., Ltd.
Tel
17301778918
Country
CHINA
ProdList
105
Advantage
58
Neobioscience Co., Ltd.
Tel
--
Fax
--
Email
info@neobioscience.com
Country
CHINA
ProdList
6207
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58
Proteintech China
Tel
--
Fax
--
Email
Proteintech-CN@ptglab.com
Country
CHINA
ProdList
6290
Advantage
58
Beijing Baiao Innovation Technology Co., Ltd.
Tel
--
Fax
--
Email
3007606172@qq.com
Country
CHINA
ProdList
6002
Advantage
58
Resenbio
Tel
--
Fax
--
Email
sales@xarxbio.com
Country
China
ProdList
1774
Advantage
50
Beijing Bolide Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1985563437@qq.com
Country
CHINA
ProdList
6525
Advantage
58
Beijing Shengke Boyuan Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
978560024@qq.com
Country
CHINA
ProdList
6458
Advantage
58
Beijing Taize Jiaye Technology Development Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6050
Advantage
58
Shanghai Chaoyan Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
471161314@qq.com
Country
CHINA
ProdList
6210
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
market@xlswkj.com
Country
CHINA
ProdList
6793
Advantage
58
Beijing Zhijie Fangyuan Technology Co., Ltd.
Tel
--
Fax
--
Email
15810200961@163.com
Country
CHINA
ProdList
6643
Advantage
58
Shanghai Haoran Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
470003480@QQ.COM
Country
CHINA
ProdList
6955
Advantage
58
Shanghai Silk Dragon Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
3988
Advantage
58
Beijing Bai Ao Si Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
yangmei@bioneeds.net
Country
CHINA
ProdList
6999
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Beijing Dongge Boye Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1861586486@qq.com
Country
CHINA
ProdList
6648
Advantage
58
Boao Pike
Tel
--
Fax
--
Email
lyn@biopike.com.cn
Country
CHINA
ProdList
6646
Advantage
58
Beijing Taize Ruida Technology Co., Ltd.
Tel
--
Fax
--
Email
taizeorder@163.com
Country
CHINA
ProdList
6536
Advantage
58
Shanghai Jijin Chemical Technology Co., Ltd.
Tel
--
Fax
--
Email
jijinhuaxue@sina.com
Country
CHINA
ProdList
6606
Advantage
58
Beijing Fubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
info@f-biology.com
Country
CHINA
ProdList
6170
Advantage
58
Morning Student Science and Technology (Guangzhou) Co., Ltd.
Tel
--
Fax
--
Email
chenxue_gz@163.com
Country
CHINA
ProdList
6600
Advantage
58
Shanghai Minmin Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1914109725@qq.com
Country
CHINA
ProdList
6518
Advantage
58
Shenzhen Xinbosheng Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
service@neobioscience.com
Country
CHINA
ProdList
6151
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
shxiyuanbio@163.com
Country
CHINA
ProdList
6906
Advantage
58
Shanghai Weiwei Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
sales@wheybio.com
Country
CHINA
ProdList
4398
Advantage
58
Shanghai Ziqi Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
2453006496@qq.com
Country
CHINA
ProdList
6184
Advantage
58
Shanghai Yaoyun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
912529879@qq.com
Country
CHINA
ProdList
6448
Advantage
58
Xiamen Huijia Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6973
Advantage
58
Xiamen Research Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1562893815@qq.com
Country
CHINA
ProdList
6936
Advantage
58
Guangzhou WeiBo Chemical Co., Ltd.
Tel
--
Fax
--
Email
weibochem@163.com
Country
China
ProdList
6187
Advantage
67

146672-58-4, PAPA NONOATERelated Search:

Sodium nitroprusside dihydrate NOC-18 NOC-7 MAHMA NONOATE 4-(N-CYANOMETHYL-N-NITROSO)AMINOMORPHOLINE S-NITROSOGLUTATHIONE NOC-5 DEA NONOate GEA 5024 Vorinostat NOC-12 V-PYRRO/NO GEA 3162 BETA-GAL-NONOATE NOR-3 DPTA NONOATE SPERMINE NONOATE PAPA NONOATE

  • 3-(2-HYDROXY-2-NITROSO-1-PROPYLHYDRAZINO)-1-PROPANAMINE NONOATE
  • 1-HYDROXY-2-OXO-3-(3-AMINOPROPYL)-3-PROPYL-1-TRIAZENE
  • (Z)-1-[N-(3-AMMONIOPROPYL)-N-(N-PROPYL)AMINO]DIAZEN-1-IUM-1,2-DIOLATE
  • (Z)-1-[N-(3-AMINOPROPYL)-N-)B-PROPYL)AMINO]DIAZIN-1-IUM-1,2-DIOLATE
  • PROPYLAMINE PROPYLAMINE NONOATE
  • PAPA/NO
  • PAPA NONOATE
  • NOC-15
  • NOC-15 NONOATE
  • PAPA NONATE
  • 3-(2-hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine
  • 3-(2-Hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine, NOC-15
  • 3-[[nitroso(oxido)amino]-propylamino]propylazanium
  • 1-Propanamine, 3-(2-hydroxy-2-nitroso-1-propylhydrazinyl)-
  • PAPA NONOate, Nitric oxide (NO) donor
  • 146672-58-4
  • C6H16N4O2
  • NO Donors
  • Enzymes, Inhibitors, and Substrates
  • Nitric Oxide Metabolism
  • BioChemical
  • Biochemicals and Reagents
  • Cell Signaling Enzymes
  • Application Index