MAHMA NONOATE

Product Name: MAHMA NONOATE
CAS No.: 146724-86-9
Chemical Name: MAHMA NONOATE
Synonyms: NOC-9;MAHMA/NO;MAHMA NONOATE;noc-9crystalline;MAHMA NONOate,97%;METHYLAMINE HEXAMETHYLENE METHYLAMINE NONOATE;methyl-[6-[methyl-[nitroso(oxido)amino]amino]hexyl]azanium;1-HYDROXY-2-OXO-3-(N-METHYL-6-AMINOHEXYL)-3 METHYL-1-TRIAZENE;6-(2-HYDROXY-1-METHYL-2-NITROSOHYDRAZINO)-N-METHYL-1-HEXANAMINE;1-Hexanamine, 6-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)-N-methyl-
CBNumber: CB4152738
Molecular Formula: C8H20N4O2
Formula Weight: 204.27
MOL File: 146724-86-9.mol

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MAHMA NONOATE Property

Melting point:: 102-108 °C
Boiling point:: 301.7±44.0 °C(Predicted)
Density: 1.10±0.1 g/cm3(Predicted)
storage temp.: −70°C
solubility: Soluble in water highly
form: White to off-white crystalline solid.
pka: 0.45±0.69(Predicted)
color: Off-white to light yellow

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29270000

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M1555
Product name: MAHMA NONOate
Packaging: 50mg
Price: $148
Updated: 2025/07/31

Cayman Chemical

Product number: 82130
Product name: MAHMA NONOate
Purity: ≥98%
Packaging: 10mg
Price: $36
Updated: 2024/03/01

Cayman Chemical

Product number: 82130
Product name: MAHMA NONOate
Purity: ≥98%
Packaging: 25mg
Price: $72
Updated: 2024/03/01

Cayman Chemical

Product number: 82130
Product name: MAHMA NONOate
Purity: ≥98%
Packaging: 50mg
Price: $108
Updated: 2024/03/01

Cayman Chemical

Product number: 82130
Product name: MAHMA NONOate
Purity: ≥98%
Packaging: 100mg
Price: $179
Updated: 2024/03/01

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MAHMA NONOATE Chemical Properties,Usage,Production

Description

MAHMA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 1 minute and 3 minutes at 37°C and 22-25°C, respectively, (pH 7.4) to liberate 2 moles of NO per mole of parent compound.

Chemical Properties

white to off-white crystalline solid

Uses

MAHMA NONOate is a diazeniumdiolate quick-releasing NO donor.

in vivo

MAHMA NONOate (0.3-10 nmol/kg/min; i.v. once) shows both platelet inhibitory and vasodepressor effects in vivo^[2].

Animal Model:	Male Wistar rats anaesthetised with pentobarbitone^[2]
Dosage:	0.3-10 nmol/kg/min
Administration:	Intravenous injection; 0.3-10 nmol/kg/min once
Result:	Dose-dependently decreased in mean systemic artery pressure and showd a more potent effect than GSNO. Caused dose-dependent inhibition of the response to 0.3 μM/kg ADP.

References

[1] L K KEEFER. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms.[J]. Methods in enzymology, 1996, 268: 281-293. DOI: 10.1016/s0076-6879(96)68030-6
[2] TENG LI. Rational Design and Bioimaging Applications of Highly Specific “Turn-On” Fluorescent Probe for Hypochlorite[J]. Bioconjugate Chemistry Bioconjugate, 2018, 29 8: 2838-2845. DOI: 10.1021/acs.bioconjchem.8b00430

MAHMA NONOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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MAHMA NONOATE Suppliers

Belgium 1 CHINA 44 Germany 1 Japan 1 Switzerland 2 United Kingdom 4 United States 13 Global 66

Meryer (Shanghai) Chemical Technology Co., Ltd.

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Shanghai Aladdin Bio-Chem Technology Co.,LTD

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Shanghai YuanYe Biotechnology Co., Ltd.

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Shandong Ono Chemical Co., Ltd.

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Energy Chemical

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MedBioPharmaceutical Technology Inc

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TargetMol Chemicals Inc.

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Shanghai Maclean Biochemical Technology Co., LTD

Tel: 021-021-50706066 15221275939
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146724-86-9, MAHMA NONOATERelated Search:

Sodium nitroprusside dihydrate NOC-18 DPTA NONOATE SPERMINE NONOATE NOC-7 4-(N-CYANOMETHYL-N-NITROSO)AMINOMORPHOLINE S-NITROSOGLUTATHIONE NOC-5 DEA NONOate GEA 5024 NOC-12 V-PYRRO/NO PAPA NONOATE GEA 3162 BETA-GAL-NONOATE NOR-3 MAHMA NONOATE

MAHMA/NO

MAHMA NONOATE

METHYLAMINE HEXAMETHYLENE METHYLAMINE NONOATE

(Z)-1-[N-METHYL-N-[6-(N-METHYLAMMONIOHEXYL)AMINO]]DIAZEN-1-IUM-1,2-DIOLATE

noc-9crystalline

1-HYDROXY-2-OXO-3-(N-METHYL-6-AMINOHEXYL)-3 METHYL-1-TRIAZENE

6-(2-HYDROXY-1-METHYL-2-NITROSOHYDRAZINO)-N-METHYL-1-HEXANAMINE

NOC-9

NOC-9, 6-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-hexanamine

MAHMA NONOate,97%

MAHMA NONOATE;1-HYDROXY-2-OXO-3(N-METHYL-6-AMINOHEXYL)-3-METHYL-1-TRIAZENE;NOC-9

methyl-[6-[methyl-[nitroso(oxido)amino]amino]hexyl]azanium

1-Hexanamine, 6-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)-N-methyl-

146724-86-9

C8H20N4O2

NO Donors

Nitric Oxide Metabolism

Enzymes, Inhibitors, and Substrates

Biochemicals and Reagents

Application Index

BioChemical

Cell Signaling Enzymes