MAHMA NONOATE
- Product Name
- MAHMA NONOATE
- CAS No.
- 146724-86-9
- Chemical Name
- MAHMA NONOATE
- Synonyms
- NOC-9;MAHMA/NO;MAHMA NONOATE;noc-9crystalline;MAHMA NONOate,97%;METHYLAMINE HEXAMETHYLENE METHYLAMINE NONOATE;methyl-[6-[methyl-[nitroso(oxido)amino]amino]hexyl]azanium;1-HYDROXY-2-OXO-3-(N-METHYL-6-AMINOHEXYL)-3 METHYL-1-TRIAZENE;6-(2-HYDROXY-1-METHYL-2-NITROSOHYDRAZINO)-N-METHYL-1-HEXANAMINE;1-Hexanamine, 6-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)-N-methyl-
- CBNumber
- CB4152738
- Molecular Formula
- C8H20N4O2
- Formula Weight
- 204.27
- MOL File
- 146724-86-9.mol
MAHMA NONOATE Property
- Melting point:
- 102-108 °C
- Boiling point:
- 301.7±44.0 °C(Predicted)
- Density
- 1.10±0.1 g/cm3(Predicted)
- storage temp.
- −70°C
- solubility
- Soluble in water highly
- form
- White to off-white crystalline solid.
- pka
- 0.45±0.69(Predicted)
- color
- Off-white to light yellow
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29270000
N-Bromosuccinimide Price
- Product number
- M1555
- Product name
- MAHMA NONOate
- Packaging
- 50mg
- Price
- $148
- Updated
- 2025/07/31
- Product number
- 82130
- Product name
- MAHMA NONOate
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $36
- Updated
- 2024/03/01
- Product number
- 82130
- Product name
- MAHMA NONOate
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $72
- Updated
- 2024/03/01
- Product number
- 82130
- Product name
- MAHMA NONOate
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $108
- Updated
- 2024/03/01
- Product number
- 82130
- Product name
- MAHMA NONOate
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $179
- Updated
- 2024/03/01
MAHMA NONOATE Chemical Properties,Usage,Production
Description
MAHMA NONOate is a NO donor. It spontaneously dissociates in a pH-
Chemical Properties
white to off-white crystalline solid
Uses
MAHMA NONOate is a diazeniumdiolate quick-releasing NO donor.
in vivo
MAHMA NONOate (0.3-10 nmol/kg/min; i.v. once) shows both platelet inhibitory and vasodepressor effects in vivo[2].
| Animal Model: | Male Wistar rats anaesthetised with pentobarbitone[2] |
| Dosage: | 0.3-10 nmol/kg/min |
| Administration: | Intravenous injection; 0.3-10 nmol/kg/min once |
| Result: | Dose-dependently decreased in mean systemic artery pressure and showd a more potent effect than GSNO. Caused dose-dependent inhibition of the response to 0.3 μM/kg ADP. |
References
[1] L K KEEFER. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms.[J]. Methods in enzymology, 1996, 268: 281-293. DOI: 10.1016/s0076-6879(96)68030-6
[2] TENG LI. Rational Design and Bioimaging Applications of Highly Specific “Turn-On” Fluorescent Probe for Hypochlorite[J]. Bioconjugate Chemistry Bioconjugate, 2018, 29 8: 2838-2845. DOI: 10.1021/acs.bioconjchem.8b00430
MAHMA NONOATE Preparation Products And Raw materials
Raw materials
Preparation Products
MAHMA NONOATE Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71