ChemicalBook > CAS DataBase List > 5-Methylthiophene-2-boronic acid

5-Methylthiophene-2-boronic acid

Product Name
5-Methylthiophene-2-boronic acid
CAS No.
162607-20-7
Chemical Name
5-Methylthiophene-2-boronic acid
Synonyms
5-METHYL-2-THIOPHENEBORONIC ACID;AKOS BRN-0271;CHEMBRDG-BB 3200980;TIMTEC-BB SBB004150;RARECHEM AH PB 0219;2-Borono-5-methylthiophene;5-METHYL-2-THIENYLBORIC ACID;5-METHYL-2-THIENYLBORONIC ACID;2-Methylthienyl-5-boronic acid;5-METHYLTHIOPHENE-2-BORONIC ACID
CBNumber
CB2691532
Molecular Formula
C5H7BO2S
Formula Weight
141.98
MOL File
162607-20-7.mol
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5-Methylthiophene-2-boronic acid Property

Melting point:
161.5-166.5 °C(lit.)
Boiling point:
302.9±44.0 °C(Predicted)
Density 
1.25±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
soluble in Methanol
form 
powder to crystal
pka
8.73±0.53(Predicted)
color 
White to Yellow to Orange
BRN 
7019569
InChI
InChI=1S/C5H7BO2S/c1-4-2-3-5(9-4)6(7)8/h2-3,7-8H,1H3
InChIKey
NRIYPIBRPGAWDD-UHFFFAOYSA-N
SMILES
B(C1SC(C)=CC=1)(O)O
CAS DataBase Reference
162607-20-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26-36-7/9-37
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
IRRITANT, KEEP COLD
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M1850
Product name
5-Methyl-2-thiopheneboronic Acid (contains varying amounts of Anhydride)
Packaging
1g
Price
$39
Updated
2025/07/31
TCI Chemical
Product number
M1850
Product name
5-Methyl-2-thiopheneboronic Acid (contains varying amounts of Anhydride)
Packaging
5g
Price
$131
Updated
2025/07/31
TRC
Product number
M725528
Product name
5-Methylthiophene-2-boronicAcid
Packaging
50mg
Price
$60
Updated
2021/12/16
Synthonix
Product number
M4600
Product name
(5-Methylthiophen-2-yl)boronicacid
Purity
96%
Packaging
1g
Price
$10
Updated
2021/12/16
Matrix Scientific
Product number
003968
Product name
5-Methylthiophene-2-boronic acid
Purity
97%
Packaging
1g
Price
$19
Updated
2021/12/16
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5-Methylthiophene-2-boronic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow powder

Uses

suzuki reaction

Uses

Reactant for:

  • Suzuki-Miyaura cross-coupling reactions

Synthesis

554-14-3

150-46-9

162607-20-7

General procedure for the synthesis of 5-methylthiophene-2-boronic acid from 2-methylthiophene and triethyl borate: 5-methylthiophene-2-boronic acid (4.42 g, 85% yield) was obtained by reacting 2-methylthiophene (3.6 g, 17.3 mmol) with n-butyllithium at -78 °C, followed by the addition of triethyl borate. Next, 5-methylthiophene-2-boronic acid (4.42 g) was reacted with methyl 5-bromo-2-iodobenzoate at 80 °C via Suzuki coupling reaction to synthesize intermediate 1 (7.78 g, 80% yield). Intermediate 1 was subsequently cyclized with CH3MgCl to give Intermediate 2 (3.14 g, 40% yield). Finally, intermediate 2 was reacted with 9-phenylanthracene boronic acid via Suzuki coupling to give compound 1 (3.3 g, 60% yield). The structure of compound 1 was confirmed by 1HNMR and mass spectrometry (MS).

References

[1] Patent: KR2015/96594, 2015, A. Location in patent: Paragraph 0290; 0291; 0292

5-Methylthiophene-2-boronic acid Preparation Products And Raw materials

Raw materials

2-Methylthiophene Tetrahydrofuran Diethyl ether Triisopropyl borate n-Butyllithium

Preparation Products

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View Lastest Price from 5-Methylthiophene-2-boronic acid manufacturers

Henan Fengda Chemical Co., Ltd
Product
5-Methylthiophene-2-boronic acid 162607-20-7
Price
US $34.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Career Henan Chemical Co
Product
5-Methylthiophene-2-boronic acid 162607-20-7
Price
US $2.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
ask
Release date
2020-01-08

162607-20-7, 5-Methylthiophene-2-boronic acidRelated Search:

Methylparaben Kresoxim-methyl 2-Chloro-5-chloromethylpyridine Bensulfuron methyl Methyl salicylate 2,5-Dimethylpyridine METHYLTHYMOL BLUE EPA METSULFURON METHYL Folic acid 5-Amino-2-methylpyridine Methylboronic acid 3-Hydroxy-2-methyl-4H-pyran-4-one 5-Methyl-2-thiophenecarboxylic acid Thiophanate-methyl Methyl Ascoric Acid Parathion-methyl

  • RARECHEM AH PB 0219
  • TIMTEC-BB SBB004150
  • CHEMBRDG-BB 3200980
  • 5-methylthiophen-2-ylboronic acid
  • AKOS BRN-0271
  • 5-METHYL-2-THIENYLBORIC ACID
  • 5-METHYL-2-THIENYLBORONIC ACID
  • 5-METHYL-2-THIOPHENEBORONIC ACID
  • 5-METHYLTHIOPHENE-2-BORONIC ACID
  • 5-METHYLTHIOPHENE-2-BORONIC ACID 97%
  • 5-Methyl-2-thiopheneboronic Acid (contains varying amounts of Anhydride)
  • 5-Methylthiophene-2-boronic acid ,98%
  • (5-methyl-2-thienyl)boronic acid(SALTDATA: FREE)
  • Boronic acid, B-(5-Methyl-2-thienyl)-
  • (5-Methylthien-2-yl)boronic acid
  • (5-Methylthiophen-2-yl)dihydroxyborane
  • 2-Methylthienyl-5-boronic acid
  • 2-Methylthiophene-5-boronic acid
  • 5-methyl-2-thiophenyl boronic acid
  • 5-Methyl-2-thiopheneboronic Acid&nbsp
  • 2-Borono-5-methylthiophene
  • (5-Methylthiophen-2-yl)boronic acid - [M4600]
  • 162607-20-7
  • BORONIC ACID
  • Boronic Acids
  • Boronic Acids and Derivatives
  • Heteroaryl
  • Organometallic Reagents
  • Boric Acid| Boric Acid Ester| Potassium Trifluoroborate
  • Boronic acid
  • Organoborons
  • Thiophene
  • B (Classes of Boron Compounds)
  • Boronic Acids
  • Boronic Acids and Derivatives
  • Heteroaryl
  • Thiophene&Benzothiophene
  • Boronic acids
  • Azoles
  • blocks
  • BoronicAcids