5-Methylthiophene-2-boronic acid
- Product Name
- 5-Methylthiophene-2-boronic acid
- CAS No.
- 162607-20-7
- Chemical Name
- 5-Methylthiophene-2-boronic acid
- Synonyms
- 5-METHYL-2-THIOPHENEBORONIC ACID;AKOS BRN-0271;CHEMBRDG-BB 3200980;TIMTEC-BB SBB004150;RARECHEM AH PB 0219;2-Borono-5-methylthiophene;5-METHYL-2-THIENYLBORIC ACID;5-METHYL-2-THIENYLBORONIC ACID;2-Methylthienyl-5-boronic acid;5-METHYLTHIOPHENE-2-BORONIC ACID
- CBNumber
- CB2691532
- Molecular Formula
- C5H7BO2S
- Formula Weight
- 141.98
- MOL File
- 162607-20-7.mol
5-Methylthiophene-2-boronic acid Property
- Melting point:
- 161.5-166.5 °C(lit.)
- Boiling point:
- 302.9±44.0 °C(Predicted)
- Density
- 1.25±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 8.73±0.53(Predicted)
- color
- White to Yellow to Orange
- BRN
- 7019569
- InChI
- InChI=1S/C5H7BO2S/c1-4-2-3-5(9-4)6(7)8/h2-3,7-8H,1H3
- InChIKey
- NRIYPIBRPGAWDD-UHFFFAOYSA-N
- SMILES
- B(C1SC(C)=CC=1)(O)O
- CAS DataBase Reference
- 162607-20-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 37/39-26-36-7/9-37
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- IRRITANT, KEEP COLD
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M1850
- Product name
- 5-Methyl-2-thiopheneboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 1g
- Price
- $39
- Updated
- 2025/07/31
- Product number
- M1850
- Product name
- 5-Methyl-2-thiopheneboronic Acid (contains varying amounts of Anhydride)
- Packaging
- 5g
- Price
- $131
- Updated
- 2025/07/31
- Product number
- M725528
- Product name
- 5-Methylthiophene-2-boronicAcid
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 003968
- Product name
- 5-Methylthiophene-2-boronic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $66
- Updated
- 2021/12/16
- Product number
- 6H60-1-W0
- Product name
- 5-Methylthiophene-2-boronic acid
- Packaging
- 5G
- Price
- $80
- Updated
- 2021/12/16
5-Methylthiophene-2-boronic acid Chemical Properties,Usage,Production
Chemical Properties
white to light yellow powder
Uses
suzuki reaction
Uses
Reactant for:
- Suzuki-Miyaura cross-coupling reactions
Synthesis
554-14-3
150-46-9
162607-20-7
General procedure for the synthesis of 5-methylthiophene-2-boronic acid from 2-methylthiophene and triethyl borate: 5-methylthiophene-2-boronic acid (4.42 g, 85% yield) was obtained by reacting 2-methylthiophene (3.6 g, 17.3 mmol) with n-butyllithium at -78 °C, followed by the addition of triethyl borate. Next, 5-methylthiophene-2-boronic acid (4.42 g) was reacted with methyl 5-bromo-2-iodobenzoate at 80 °C via Suzuki coupling reaction to synthesize intermediate 1 (7.78 g, 80% yield). Intermediate 1 was subsequently cyclized with CH3MgCl to give Intermediate 2 (3.14 g, 40% yield). Finally, intermediate 2 was reacted with 9-phenylanthracene boronic acid via Suzuki coupling to give compound 1 (3.3 g, 60% yield). The structure of compound 1 was confirmed by 1HNMR and mass spectrometry (MS).
References
[1] Patent: KR2015/96594, 2015, A. Location in patent: Paragraph 0290; 0291; 0292
5-Methylthiophene-2-boronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
5-Methylthiophene-2-boronic acid Suppliers
- Tel
- --
- Fax
- --
- synthesis@chimmed.ru
- Country
- Russia
- ProdList
- 5006
- Advantage
- 81
View Lastest Price from 5-Methylthiophene-2-boronic acid manufacturers
- Product
- 5-Methylthiophene-2-boronic acid 162607-20-7
- Price
- US $34.00-1.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 5-Methylthiophene-2-boronic acid 162607-20-7
- Price
- US $2.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- ask
- Release date
- 2020-01-08