3-Methyl-4-aminopyridine
- Product Name
- 3-Methyl-4-aminopyridine
- CAS No.
- 1990-90-5
- Chemical Name
- 3-Methyl-4-aminopyridine
- Synonyms
- 3-METHYLPYRIDIN-4-AMINE;4-AMINO-3-METHYLPYRIDINE;philips1908;Phillips-1908;-4-aminopyridine;4-amino-3-picolin;4-AMINO-3-PICOLINE;3-methyl-4-pyridinamin;4-Amino-3-picoline HCl;3-Methyl-4-pyridinamine
- CBNumber
- CB2700582
- Molecular Formula
- C6H8N2
- Formula Weight
- 108.14
- MOL File
- 1990-90-5.mol
3-Methyl-4-aminopyridine Property
- Melting point:
- 106-107
- Boiling point:
- 192.78°C (rough estimate)
- Density
- 0.9581 (rough estimate)
- refractive index
- 1.5400 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- powder to crystal
- pka
- pK1: 9.43(+1) (25°C)
- color
- Crystals from C6H6/pet ether
- InChI
- InChI=1S/C6H8N2/c1-5-4-8-3-2-6(5)7/h2-4H,1H3,(H2,7,8)
- InChIKey
- VGJLGPCXUGIXRQ-UHFFFAOYSA-N
- SMILES
- C1=NC=CC(N)=C1C
- CAS DataBase Reference
- 1990-90-5(CAS DataBase Reference)
Safety
- Hazard Codes
- C,Xi,Xn
- Risk Statements
- 23/24/25-36/37/38-34-22-20/21/22
- Safety Statements
- 22-36/37/39-45-36-27-26
- RIDADR
- 2811
- RTECS
- TJ5140000
- Hazard Note
- Harmful
- HS Code
- 29333999
- Toxicity
- LD50 orl-rat: 446 mg/kg TXAPA9 21,315,72
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CDS003217
- Product name
- 4-amino-3-methylpyridine
- Purity
- AldrichCPR
- Packaging
- 1g
- Price
- $73.1
- Updated
- 2025/07/31
- Product number
- A2283
- Product name
- 4-Amino-3-methylpyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $59
- Updated
- 2025/07/31
- Product number
- A637838
- Product name
- 4-Amino-3-methylpyridine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR8895
- Product name
- 4-Amino-3-methylpyridine
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- 3H30-1-M4
- Product name
- 4-Amino-3-methylpyridine
- Packaging
- 1g
- Price
- $16
- Updated
- 2021/12/16
3-Methyl-4-aminopyridine Chemical Properties,Usage,Production
Chemical Properties
Crystals
Uses
4-Amino-3-methylpyridine is a non depolarizing muscular relaxant with antagonist effect that functions on neuromuscular transmission and in central nervous systems in rats. A central cholinergic agent.
Safety Profile
Moderately toxic by ingestion.When heated to decomposition it emits toxic fumes ofNOx.
Synthesis
1074-98-2
1990-90-5
Step 2: A mixed solution of 3-methyl-4-nitropyridine-N-oxide (30.0 g, 195 mmol) with 10% palladium-carbon catalyst (6.0 g) in ethanol (450 mL) was subjected to a hydrogen atmosphere (5 bar) and the reaction was stirred at room temperature for 36 hours. Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad to remove the catalyst, followed by evaporation of the solvent under reduced pressure to afford the target product 3-methyl-4-aminopyridine (20.0 g, 95% yield).
References
[1] Nucleosides, Nucleotides and Nucleic Acids, 2002, vol. 21, # 11-12, p. 737 - 751
[2] Patent: WO2015/22073, 2015, A1. Location in patent: Page/Page column 39
[3] Patent: WO2005/63744, 2005, A2. Location in patent: Page/Page column 232
[4] Journal of the American Chemical Society, 1954, vol. 76, p. 4184
[5] Pharmaceutical Bulletin, 1956, vol. 4, p. 174,177
3-Methyl-4-aminopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Methyl-4-aminopyridine manufacturers
- Product
- 3-Methyl-4-aminopyridine 1990-90-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-30
- Product
- 3-Methyl-4-aminopyridine 1990-90-5
- Price
- US $10.00-8.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-12-06
- Product
- 3-Methyl-4-aminopyridine 1990-90-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-04-30