2-Methyl-4-methoxybenzenamine

Product Name: 2-Methyl-4-methoxybenzenamine
CAS No.: 102-50-1
Chemical Name: 2-Methyl-4-methoxybenzenamine
Synonyms: 4-METHOXY-2-METHYLANILINE;Benzenamine, 4-methoxy-2-methyl-;2-Methoxy-3-methylaniline;4-Methoxy-2-methylbenzenamine;AKOS 91136;NCI-C02993;M-CRESIDINE;N-cresidine;meta-cresidine;2-methyl-p-anisidin
CBNumber: CB2712327
Molecular Formula: C8H11NO
Formula Weight: 137.18
MOL File: 102-50-1.mol

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2-Methyl-4-methoxybenzenamine Property

Melting point:: 13-14 °C(lit.)
Boiling point:: 248-249 °C(lit.)
Density: 1.065 g/mL at 25 °C(lit.)
refractive index: n20/D 1.565(lit.)
Flash point:: >230 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Acetonitrile (Slightly), Chloroform (Slightly), DMSO, Methanol (Slightly)
form: Oil
pka: 5.05±0.10(Predicted)
color: Light Brown to Very Dark Red
Water Solubility: insoluble, <0.1 g/100 mL at 21.5 ºC
BRN: 774727
Stability:: Stable. May be light or air-sensitive. Combustible. Incompatible with acids, strong oxidizing agents.
InChIKey: CDGNLUSBENXDGG-UHFFFAOYSA-N
CAS DataBase Reference: 102-50-1(CAS DataBase Reference)
NIST Chemistry Reference: Benzenamine, 4-methoxy-2-methyl-(102-50-1)
IARC: 3 (Vol. 27, Sup 7) 1987
EPA Substance Registry System: m-Cresidine (102-50-1)

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Safety

Hazard Codes: Xi,Xn,T
Risk Statements: 36/37/38-40-45
Safety Statements: 26-36/37/39-53-45
RIDADR: 2810
WGK Germany: 3
RTECS: BZ6730000
TSCA: Yes
HazardClass: 6.1
PackingGroup: III
HS Code: 29222990
Hazardous Substances Data: 102-50-1(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M15001
Product name: 4-Methoxy-2-methylaniline
Purity: 98%
Packaging: 5g
Price: $79.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: M15001
Product name: 4-Methoxy-2-methylaniline
Purity: 98%
Packaging: 25g
Price: $108
Updated: 2023/06/20

TCI Chemical

Product number: M1474
Product name: 4-Methoxy-2-methylaniline
Purity: >99.0%(GC)(T)
Packaging: 25g
Price: $100
Updated: 2025/07/31

TCI Chemical

Product number: M1474
Product name: 4-Methoxy-2-methylaniline
Purity: >99.0%(GC)(T)
Packaging: 500g
Price: $892
Updated: 2025/07/31

TRC

Product number: M263620
Product name: 4-Methoxy-2-methylaniline
Packaging: 5g
Price: $50
Updated: 2021/12/16

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2-Methyl-4-methoxybenzenamine Chemical Properties,Usage,Production

Chemical Properties

brick red crystals or liquid

Uses

4-Methoxy-2-methylaniline is a reagent used in organic synthesis of more complex compounds that have a more specific function. For example, enzyme inhibitors.

Definition

ChEBI: Meta-Cresidine is a member of methoxybenzenes.

General Description

Crystals or brick red liquid.

Air & Water Reactions

Sensitive to prolonged exposure to air and light. Insoluble in water.

Reactivity Profile

2-Methyl-4-methoxybenzenamine neutralizes acids in weakly exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides. Reacts with oxidizing agents .

Health Hazard

ACUTE/CHRONIC HAZARDS: 2-Methyl-4-methoxybenzenamine is a local irritant. When heated to decomposition it emits toxic fumes of NOx. 2-Methyl-4-methoxybenzenamine is an experimental animal carcinogen.

Fire Hazard

2-Methyl-4-methoxybenzenamine is probably combustible.

Safety Profile

Suspected carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Synthesis

5367-32-8

102-50-1

GENERAL PROCEDURE: 3-methyl-4-nitroanisole (1.0 mmol), B2(OH)4 (5.0 eq., 5.0 mmol) and H2O (3.0 mL) were added to a 10 mL reaction tube. The reaction mixture was stirred at 80 °C for 8 hours. After completion of the reaction (monitored by TLC), the mixture was cooled to room temperature and extracted with ethyl acetate (3 x 20 mL). The organic phases were combined, dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to give 2-methyl-4-methoxyaniline.

References

[1] Analytical Chemistry, 1992, vol. 64, # 8, p. 837 - 842
[2] ChemCatChem, 2017, vol. 9, # 16, p. 3236 - 3244
[3] Synlett, 2018, vol. 29, # 13, p. 1765 - 1768
[4] Tetrahedron, 2017, vol. 73, # 27-28, p. 3898 - 3904
[5] Helvetica Chimica Acta, 1924, vol. 7, p. 698

2-Methyl-4-methoxybenzenamine Preparation Products And Raw materials

Raw materials

3-Methyl-4-nitrophenol Hydrazinium hydroxide solution Sodium Palladium Sodium Methoxide Hydrochloric acid Sodium bicarbonate Methanol Iron Dimethyl sulfate

Preparation Products

NAPHTHOL AS-LT 2-Hydroxy-N-(4-methoxy-2-methylphenyl)-11H-benzo[a]carbazole-3-carboxamide

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2-Methyl-4-methoxybenzenamine Suppliers

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View Lastest Price from 2-Methyl-4-methoxybenzenamine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2-Methyl-4-methoxybenzenamine 102-50-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-25

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Methyl-4-methoxybenzenamine 102-50-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-13

Shaanxi Dideu New Materials Co. Ltd

Product: 2-Methyl-4-methoxybenzenamine 102-50-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-19

102-50-1, 2-Methyl-4-methoxybenzenamineRelated Search:

6-NITROPIPERONYL ALCOHOL 2-Methyl-4-methoxybenzenamine 6-Nitroveratraldehyde 4-METHOXY-2-METHYLPHENYL ISOCYANATE ETHYL 4,5-DIMETHOXY-2-NITROBENZOATE D-ribo-Hexanoic acid, 3-deoxy-, γ-lactone 2,3-DIMETHYL-4-NITROANISOLE Methyl 2-amino-3,4,5-trimethoxybenzoate 4,5-DIMETHOXY-2-NITROBENZYL ALCOHOL BRUCINE SULFATE 6-NITROPIPERONAL Methyl 4,5-dimethoxy-2-nitrobenzoate Methyl 2-amino-4,5-dimethoxybenzoate 2-Amino-5-methoxybenzoic acid Methyl 2-nitro-3,4,5-trimethoxybenzoate 2-Amino-4,5-dimethoxybenzoic acid 3-Methyl-4-nitroanisole 2-Methoxy-5-methylaniline

AKOS 91136

6-AMINO-3-METHOXYTOLUENE

4-METHOXY-2-METHYLANILINE

4-METHOXY-O-TOLUIDINE

3-METHYL-4-AMINOANISOLE

2-METHYL-P-ANISIDINE

2-METHYL-4-METHOXYBENZENAMINE

1-AMINO-4-METHOXY-2-METHYLBENZENE

M-CRESIDINE

1-Amino-4-methoxy-2-methylbenzene m-Cresidine 4-Methoxy-o-toluidine

2-Amino-5-methoxytoluene, 4-Amino-3-methylanisole, 2-Methyl-p-anisidine, 4-Methoxy-o-toluidine

4-Methoxy-2-Methylaniline, 98% 5GR

4-AMino-3-Methylanisole[4-Methoxy-2-Methylaniline]

4-Methoxy-2-Methylaniline , 98.0%(GC&T

4-Methoxy-2-methyl-phenylamine

Benzenamine, 4-methoxy-2-methyl-

4-Amino-3-methylanisole

2-Methyl-4-methoxybenzemine

4-Methoxy-2-methylaniline (m-Cresidine)

2-Amino-5-Methoxytoluene

4-METHOXY-2-METHYLANILINE 98.5%

2-Amino-5-methoxytoluene, 4-Amino-3-methylanisole

2-Methyl-p-anisidine, m-Cresidine

2-methyl-p-anisidin

4-methoxy-2-methyl-benzenamin

4-Methoxy-2-methylbenzenamine

NCI-C02993

p-Anisidine, 2-methyl-

2-Methyl-4-Methoxybenzenamine 2-Amino-5-Methoxytoluene

5-methoxy-2-methylbenzenamine

meta-cresidine

2-Methyl-p-anisidine(NH2=1)

N-[1,2-Dihydroxy-2-(prop-2-enoylamino)ethyl]prop-2-enamide

4-Methoxy-2-methylaniline ,98%

N-cresidine

2-Methoxy-3-methylaniline

2-Methyl-4-emthoxyaniline

4-Methoxy-2-methylaniline&gt

2-Methyl-4-methoxybenzenamine ISO 9001：2015 REACH

2-Methyl-4-(methyloxy)aniline

4-Methoxy-2-methylaniline, ≥ 98.0%

4-Amino-m-metylanisole

102-50-1

CH3OC6H3CH3NH2

Organic Building Blocks

Nitrogen Compounds

Amines

Building Blocks

C8

Amines and Anilines

Intermediates of Dyes and Pigments

Amines

Building Blocks

C8 to C9

Chemical Synthesis

Nitrogen Compounds

Organic Building Blocks