4-Fluoro-2-nitroanisole
- Product Name
- 4-Fluoro-2-nitroanisole
- CAS No.
- 445-83-0
- Chemical Name
- 4-Fluoro-2-nitroanisole
- Synonyms
- 4-Fluoro-2-nitroanis;4-FLUORO-2-NITROANISOLE;4-Fluoro-2-nitroanisole>4-Fluoro-2-nitroanisole98%;4-Fluoro-2-nitroanisole 98%;4-Fluoro-2-nitro-methoxybenzene;445-83-0 4-Fluoro-2-nitroanisole;4-FLUORO-1-METHOXY-2-NITROBENZENE;1-Methoxy-2-nitro-4-fluorobenzene;Benzene, 4-fluoro-1-methoxy-2-nitro-
- CBNumber
- CB2771333
- Molecular Formula
- C7H6FNO3
- Formula Weight
- 171.13
- MOL File
- 445-83-0.mol
4-Fluoro-2-nitroanisole Property
- Melting point:
- 62-64 °C (lit.)
- Boiling point:
- 272.4±20.0 °C(Predicted)
- Density
- 1.321±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- soluble in Toluene
- form
- powder to crystal
- color
- Light orange to Yellow to Green
- CAS DataBase Reference
- 445-83-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 324760
- Product name
- 4-Fluoro-2-nitroanisole
- Purity
- 98%
- Packaging
- 5g
- Price
- $56.7
- Updated
- 2022/05/15
- Product number
- F0615
- Product name
- 4-Fluoro-2-nitroanisole
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $78
- Updated
- 2025/07/31
- Product number
- F0615
- Product name
- 4-Fluoro-2-nitroanisole
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $248
- Updated
- 2025/07/31
- Product number
- F597590
- Product name
- 4-Fluoro-2-nitroanisole
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- F597590
- Product name
- 4-Fluoro-2-nitroanisole
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
4-Fluoro-2-nitroanisole Chemical Properties,Usage,Production
Chemical Properties
Yellow powder
General Description
4-Fluoro-2-nitroanisole is formed during the photolysis of the charge transfer complex of tetranitromethane and 4-fluoroanisole in dichloromethane at -20°C.
Synthesis
394-33-2
74-88-4
445-83-0
General procedure for the synthesis of 2-nitro-4-fluoroanisole from 2-nitro-4-fluorophenol and iodomethane: Acetonitrile (100 mL) solution of iodomethane (127.8 g, 0.9004 mol) was added slowly and dropwise to an acetonitrile (450 mL) solution containing 5-fluoro-2-nitrophenol (94.2 g, 0.600 mol) and potassium carbonate (207 g, 1.50 mol). mL) solution. The reaction mixture was heated to reflux for 15 hours. Upon completion of the reaction, the mixture was cooled to room temperature, filtered to remove insoluble solids, and the filter cake was washed twice with dichloromethane (100 mL). The filtrate and washings were combined and the solvent was evaporated to dryness by rotary evaporator to afford the crude product 2-nitro-4-fluoroanisole (96 g, 0.56 mol, 93% yield), which could be used in subsequent reactions without further purification.
References
[1] Patent: WO2005/26137, 2005, A2. Location in patent: Page/Page column 230-231
[2] Synthetic Communications, 1989, vol. 19, # 1, 2, p. 233 - 238
4-Fluoro-2-nitroanisole Preparation Products And Raw materials
Raw materials
Preparation Products
4-Fluoro-2-nitroanisole Suppliers
- Tel
- --
- Fax
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- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
View Lastest Price from 4-Fluoro-2-nitroanisole manufacturers
- Product
- 4-Fluoro-2-nitroanisole 445-83-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2025-03-13
- Product
- 4-Fluoro-2-nitroanisole 445-83-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-17
- Product
- 4-Fluoro-2-nitroanisole 445-83-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10