SINOVA SL-02580

Product Name: SINOVA SL-02580
CAS No.: 357263-13-9
Chemical Name: SINOVA SL-02580
Synonyms: CS-1404;BMS-806;BMS 806;DCC-2036;SINOVA SL-02580;BMS 806;BMS-806;BMS378806|||BMS-806;BMS-806 (BMS 378806);BMS-378806 BMS378806;BMS-806; BMS 378806; BMS 806; BMS378806; BMS806
CBNumber: CB2818106
Molecular Formula: C22H22N4O4
Formula Weight: 406.43
MOL File: 357263-13-9.mol

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SINOVA SL-02580 Property

Melting point:: 236 °C
Density: 1.328
storage temp.: Store at -20°C
solubility: insoluble in H2O; insoluble in EtOH; ≥20.2 mg/mL in DMSO
form: solid
pka: 11.99±0.40(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18525
Product name: BMS-806
Purity: ≥98%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 18525
Product name: BMS-806
Purity: ≥98%
Packaging: 5mg
Price: $193
Updated: 2024/03/01

Cayman Chemical

Product number: 18525
Product name: BMS-806
Purity: ≥98%
Packaging: 10mg
Price: $341
Updated: 2024/03/01

TRC

Product number: B595905
Product name: BMS806
Packaging: 25mg
Price: $1010
Updated: 2021/12/16

ApexBio Technology

Product number: B1533
Product name: BMS-378806
Packaging: 100mg
Price: $1029
Updated: 2021/12/16

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SINOVA SL-02580 Chemical Properties,Usage,Production

Description

BMS-806 is a small molecule that inhibits the first step of HIV-1 infection by blocking the binding of host cell CD4 with viral gp120 protein. It binds the exterior envelope glycoprotein gp120 (K_d= 21.1 nM; K_i = 24.9 nM), blocking the conformational change that occurs with CD4 binding and preventing fusion of the viral and target cell membranes. BMS-806 is specific to HIV-1 irrespective of chemokine receptor preference, with no activity against HIV-2, SIV, or a panel of additional viruses.

Uses

BMS 806 is a small molecular inhibitor of HIV-1 virus which blocks the interaction between gp120 and CD4 cells.

target

CD4-gp120 interactions

References

[1] wang t1, zhang z, wallace ob, deshpande m, fang h, yang z, zadjura lm, tweedie dl, huang s, zhao f, ranadive s, robinson bs, gong yf, ricarrdi k, spicer tp, deminie c, rose r, wang hg, blair ws, shi py, lin pf, colonno rj, meanwell na. discovery of 4-benzoyl-1-[(4-methoxy-1h- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (r)-methylpiperazine (bms-378806): a novel hiv-1 attachment inhibitor that interferes with cd4-gp120 interactions. j med chem. 2003 sep 25;46(20):4236-9.

SINOVA SL-02580 Preparation Products And Raw materials

Raw materials

Preparation Products

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SINOVA SL-02580 Suppliers

China 56 United States 13 Global 69

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
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AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
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BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
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Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
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Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
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InvivoChem

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Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
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Cckinase, Inc.

Tel: +1 (732)236-3202
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ProdList: 2738
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Aladdin Scientific

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TargetMol Chemicals Inc.

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Alfa Chemistry

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Cayman Chemical Company

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Creative Enzymes

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Sinova Inc.

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View Lastest Price from SINOVA SL-02580 manufacturers

Career Henan Chemical Co

Product: SINOVA SL-02580 357263-13-9
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2019-12-25

357263-13-9, SINOVA SL-02580Related Search:

Benzylamine 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol Tenofovir disoproxil fumarate BMS707035 Avagacestat (BMS-708163) AC480 (BMS-599626) BMS-754807 7-AZAINDOLE-3-CARBOXALDEHYDE SINOVA SL-02580 1-((R)-4-BENZOYL-2-METHYL-PIPERAZIN-1-YL)-2-(4-METHOXY-7-OXY-1H-PYRROLO[2,3-B]PYRIDIN-3-YL)-ETHANE-1,2-DIONE Ethanone, 1-(1H-pyrrolo[2,3-b]pyridin-3-yl)- (9CI) 4-HYDROXY-7-AZAINDOLE (R)-2-METHYL-4-BENZOYLPIPERAZINE 4-METHOXY-7-AZAINDOLE

SINOVA SL-02580

DCC-2036

BMS 806

BMS-806

BMS-806 (BMS 378806)

1-[(2R)-4-Benzoyl-2-methyl-1-piperazinyl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)-1,2-ethanedione

(R)-1-(4-benzoyl-2-methylpiperazin-1-yl)-2-(4-methoxy-7H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione

BMS 806;BMS-806

CS-1404

BMS-806; BMS 378806; BMS 806; BMS378806; BMS806

BMS-378806 BMS378806

BMS 378806,BMS 806,Human immunodeficiency virus,inhibit,HIV,BMS-378806,BMS806,Inhibitor

1,2-Ethanedione, 1-[(2R)-4-benzoyl-2-methyl-1-piperazinyl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)-

BMS378806|||BMS-806

(R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione

357263-13-9

Inhibitors