ChemicalBook > CAS DataBase List > tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate

tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate

Product Name
tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate
CAS No.
916420-27-4
Chemical Name
tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate
Synonyms
tert-butyl 2,4-dichloro-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate;7-Boc-2,4-dichloro-5,6,7,...;TERT-BUTYL 2,4-DICHLORO-5,6-DIHYDROPYRIDO;tert-butyl2,4-dichloro-5,6-d]pyrimidine-7(8H)-carboxylate;2,4-Dichloro-7-Boc-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine;7-Boc-2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine;tert-butyl 2,4-dichloro-6,8-dihydro-5H-pyrido[3,4-d]pyrimidi...;tert-butyl 2,4-dichloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate;ert-Butyl2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate;ter-butyl 2,4-dichloro-5,6-dihydropyido[3,4-d]pyrimidine-7(8H)-carboxylate
CBNumber
CB2823351
Molecular Formula
C12H15Cl2N3O2
Formula Weight
304.17
MOL File
916420-27-4.mol
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tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate Property

Boiling point:
423.1±45.0 °C(Predicted)
Density 
1.352±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-1.95±0.20(Predicted)
Appearance
White to light yellow Solid
InChI
InChI=1S/C12H15Cl2N3O2/c1-12(2,3)19-11(18)17-5-4-7-8(6-17)15-10(14)16-9(7)13/h4-6H2,1-3H3
InChIKey
SAEOMPAQDWZLHC-UHFFFAOYSA-N
SMILES
C1(Cl)=NC(Cl)=C2CCN(C(OC(C)(C)C)=O)CC2=N1
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B807125
Product name
tert-Butyl2,4-Dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate
Packaging
50mg
Price
$45
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
L14620
Product name
tert-Butyl2,4-dichloro-5,6-dihydropyrido[34-d]pyrimidine-7(8H)-carboxylate
Purity
98%
Packaging
5g
Price
$220
Updated
2021/12/16
Apolloscientific
Product number
OR480873
Product name
tert-Butyl2,4-dichloro-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-7-carboxylate
Purity
97%
Packaging
1g
Price
$254
Updated
2021/12/16
Matrix Scientific
Product number
069996
Product name
tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate
Purity
>95%
Packaging
1g
Price
$265
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-5-9V
Product name
tert-Butyl 2,4-dichloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate
Purity
97.0%
Packaging
250mg
Price
$290
Updated
2021/12/16
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tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate Chemical Properties,Usage,Production

Uses

tert-Butyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxylate (tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate) can be used as an intermediate for laboratory R&D.

Synthesis

tert-Butyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxylate can be prepared by Intermediate 4 in DCM stirred with (Boc)2O and TEA at room temperature for 16 hours.

References

[1] Patent: WO2014/15291, 2014, A1. Location in patent: Page/Page column 174; 175

tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate Suppliers

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View Lastest Price from tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
tert-Butyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxylate 916420-27-4
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-07-29
Shaanxi Dideu Medichem Co. Ltd
Product
TERT-BUTYL 2,4-DICHLORO-5,6-DIHYDROPYRIDO[3,4-D]PYRIMIDINE-7(8H)-CARBOXYLATE 916420-27-4
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-13
Henan Aochuang Chemical Co.,Ltd.
Product
tert-Butyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxylate 916420-27-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26

916420-27-4, tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylateRelated Search:

TERT-BUTYL 2,4-DICHLORO-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDINE-6(5H)-CARBOXYLATE TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE 2,4-Dichloro-6-methoxypyrimidine 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine HCl salt 2,4-Dichloro-3-iodopyridine 2,4-DIBROMO-3-CHLOROPYRIDINE 7-Benzyl-2,4-dichloro-5,6... 2,4-Dibromothiazole-5-methanol 2,4-DIBROMO-5-NITROPYRIDINE 2,4-dichloro-6-phenylpyrimidine 2,4-dichloro-5-iodo-6-methylpyrimidine CHEMPACIFIC 38112 2,4-DIBROMOBENZOTHIAZOLE 5-Thiazolecarboxylic acid, 2,4-dibromo- tert-Butyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate 2,4-Dichloro-5-methylpyrimidine 2-Chloro-5-ethylpyrimidine ethyl 5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylate

  • tert-Butyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxylate 7-Boc-2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
  • tert-butyl 2,4-dichloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate
  • tert-butyl 2,4-dichloro-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-7-carboxylate
  • TERT-BUTYL 2,4-DICHLORO-5,6-DIHYDROPYRIDO[3,4-D]PYRIMIDINE-7(8H)-CARBOXYLATE
  • 7-Boc-2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
  • tert-Butyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxylate
  • 2,4-Dichloro-7-Boc-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
  • 7-Boc-2,4-dichloro-5,6,7,...
  • 2,4-Dichloro-5,8-dihydro-6H-pyrido[3,4-d]pyriMidine-7-carboxylic acid tert-butyl ester
  • 2,4-dichloro-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-7-carboxylic acid tert-butyl ester
  • TERT-BUTYL 2,4-DICHLORO-5,6-DIHYDROPYRIDO
  • tert-butyl 2,4-dichloro-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate
  • ert-Butyl2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate
  • TERT-BUTYL 2,4-DICHLORO-5,6-DIHYDROPYRIDO[3,4-D]PYRIMIDINE-7(8H)-CARBOXYLATE ISO 9001：2015 REACH
  • tert-butyl 2,4-dichloro-6,8-dihydro-5H-pyrido[3,4-d]pyrimidi...
  • tert-butyl2,4-dichloro-5,6-d]pyrimidine-7(8H)-carboxylate
  • 1,1-Dimethylethyl 2,4-dichloro-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate
  • ter-butyl 2,4-dichloro-5,6-dihydropyido[3,4-d]pyrimidine-7(8H)-carboxylate
  • 916420-27-4
  • Heterocycle-Pyrimidine series
  • CHIRAL CHEMICALS
  • 916420-27-4