Pomalidomide-6-2-2-6-N3

Product Name: Pomalidomide-6-2-2-6-N3
CAS No.: 2300178-66-7
Chemical Name: Pomalidomide-6-2-2-6-N3
Synonyms: Poma-6-2-2-6-N3;Pomalidomide-6-2-2-6-N3;Pomalidomid-C6-PEG3-butyl-N3;Pomalidomide-C?-PEG?-butyl azide;Pomalidomide-C₆-PEG₃-butyl azide;Hexanamide, 6-[2-[2-[(6-azidohexyl)oxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
CBNumber: CB28363888
Molecular Formula: C29H40N6O8
Formula Weight: 600.67
MOL File: 2300178-66-7.mol

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Pomalidomide-6-2-2-6-N3 Property

storage temp.: 2-8°C
form: powder or crystals

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 904686
Product name: Pomalidomide-C6-PEG3-butyl azide
Purity: ≥95%
Packaging: 50MG
Price: $685
Updated: 2025/07/31

Iris Biotech GmbH

Product number: PTC1560
Product name: Pomalidomid-C6-PEG3-butyl-N3
Packaging: 50mg
Price: $634.5
Updated: 2021/12/16

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Pomalidomide-6-2-2-6-N3 Chemical Properties,Usage,Production

Uses

Protein degrader builiding block Pomalidomide-C₆-PEG₃-Butyl Azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand, a linker with both hydrophobic and hydrophilic moieties, and a pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

reaction suitability

reaction type: click chemistry
reagent type: ligand-linker conjugate

Pomalidomide-6-2-2-6-N3 Preparation Products And Raw materials

Raw materials

Preparation Products

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Pomalidomide-6-2-2-6-N3 Suppliers

China 10 United States 2 Global 12

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
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Jilin Province Woda Biotechnology Co., Ltd.

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Alfa Chemistry

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Zhengzhou convergence chemical co., LTD

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ShenZhen Trendseen Biological Technology Co.,Ltd.

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Xi‘an Deeptech Biotechnology Co.,LTD

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Henan Mengtai Pharmaceutical Technology Co., Ltd

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Merck KGaA

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Dipag (Weinan) Biotechnology Co., Ltd

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Aladdin Scientific

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View Lastest Price from Pomalidomide-6-2-2-6-N3 manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Pomalidomide-6-2-2-6-N3 2300178-66-7
Price: US $0.00/mg
Min. Order: 100mg
Purity: >95.00%
Supply Ability: 100mg
Release date: 2024-04-01

2300178-66-7, Pomalidomide-6-2-2-6-N3Related Search:

E3 ligase Ligand-Linker Conjugates 49 Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide 6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid Pomalidomide-C6-PEG3-butyl iodide POMALIDOMIDE-C9-CO2H Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl E3 ligase Ligand-Linker Conjugates 55 1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) Pomalidomide-amido-C1-Br Pomalidomide-C6-NH2?hydrochloride Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Heptanoic acid, 7-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

Pomalidomide-6-2-2-6-N3

Poma-6-2-2-6-N3

Pomalidomide-C?-PEG?-butyl azide

Pomalidomid-C6-PEG3-butyl-N3

Hexanamide, 6-[2-[2-[(6-azidohexyl)oxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-

Pomalidomide-C<sub>6</sub>-PEG<sub>3</sub>-butyl azide

2300178-66-7