ChemicalBook > CAS DataBase List > Pomalidomide-6-2-2-6-N3
Pomalidomide-6-2-2-6-N3
- Product Name
- Pomalidomide-6-2-2-6-N3
- CAS No.
- 2300178-66-7
- Chemical Name
- Pomalidomide-6-2-2-6-N3
- Synonyms
- Poma-6-2-2-6-N3;Pomalidomide-6-2-2-6-N3;Pomalidomid-C6-PEG3-butyl-N3;Pomalidomide-C?-PEG?-butyl azide;Hexanamide, 6-[2-[2-[(6-azidohexyl)oxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
- CBNumber
- CB28363888
- Molecular Formula
- C29H40N6O8
- Formula Weight
- 600.67
- MOL File
- 2300178-66-7.mol
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Pomalidomide-6-2-2-6-N3 Property
- storage temp.
- 2-8°C
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 904686
- Product name
- Pomalidomide-C6-PEG3-butyl azide
- Purity
- ≥95%
- Packaging
- 50MG
- Price
- $699
- Updated
- 2023/06/20
Iris Biotech GmbH
- Product number
- PTC1560
- Product name
- Pomalidomid-C6-PEG3-butyl-N3
- Packaging
- 50mg
- Price
- $634.5
- Updated
- 2021/12/16
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Pomalidomide-6-2-2-6-N3 Chemical Properties,Usage,Production
Uses
Protein degrader builiding block Pomalidomide-C6-PEG3-Butyl Azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand, a linker with both hydrophobic and hydrophilic moieties, and a pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.
Pomalidomide-6-2-2-6-N3 Preparation Products And Raw materials
Raw materials
Preparation Products
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Pomalidomide-6-2-2-6-N3 Suppliers
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- +86-156-80926068 +86-15680926068
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- China
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View Lastest Price from Pomalidomide-6-2-2-6-N3 manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Pomalidomide-6-2-2-6-N3 2300178-66-7
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >95.00%
- Supply Ability
- 100mg
- Release date
- 2024-04-01
2300178-66-7, Pomalidomide-6-2-2-6-N3Related Search:
E3 ligase Ligand-Linker Conjugates 49
Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide
6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid
Pomalidomide-C6-PEG3-butyl iodide
POMALIDOMIDE-C9-CO2H
Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
E3 ligase Ligand-Linker Conjugates 55
1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)
Pomalidomide-amido-C1-Br
Pomalidomide-C6-NH2?hydrochloride
Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
Heptanoic acid, 7-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-