6-Fluoro-1-tetralone
- Product Name
- 6-Fluoro-1-tetralone
- CAS No.
- 703-67-3
- Chemical Name
- 6-Fluoro-1-tetralone
- Synonyms
- 6-fluoro-3,4-dihydronaphthalen-1(2H)-one;6-fluoro-3;uoro-1-tetraL;6-FLUORTETRAL-1-ONE;5-FLUORO-L-INDOMONE;6-Fluoro-α-Tetralone;6-Fluoro-1-tetralone;6-FLU0R0-1-TETRAL0NE;6-Fluoro-1-Tetralone(WX635022);6-Fluoro-3,4-dihydro-2H-phthalen-1-one
- CBNumber
- CB2947804
- Molecular Formula
- C10H9FO
- Formula Weight
- 164.18
- MOL File
- 703-67-3.mol
6-Fluoro-1-tetralone Property
- Boiling point:
- 75 °C(Press: 0.6 Torr)
- Density
- 1.198±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- Colorless to off-white <24.5°C Solid,>24.5°C Liquid
- InChI
- InChI=1S/C10H9FO/c11-8-4-5-9-7(6-8)2-1-3-10(9)12/h4-6H,1-3H2
- InChIKey
- NJYZZEHPEKDFEK-UHFFFAOYSA-N
- SMILES
- C1(=O)C2=C(C=C(F)C=C2)CCC1
Safety
- HS Code
- 2914790090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- F598693
- Product name
- 6-Fluoro-1-tetralone
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 143354
- Product name
- 6-Fluoro-1-tetralone
- Purity
- 97%
- Packaging
- 1g
- Price
- $225
- Updated
- 2021/12/16
- Product number
- 2717-3-17
- Product name
- 6-Fluoro-1,2,3,4-tetrahydronaphthalen-1-one
- Purity
- 97%
- Packaging
- 1g
- Price
- $235
- Updated
- 2021/12/16
- Product number
- AK-29447
- Product name
- 6-Fluoro-1-tetralone
- Purity
- 97%
- Packaging
- 5g
- Price
- $273
- Updated
- 2021/12/16
- Product number
- AK-29447
- Product name
- 6-Fluoro-1-tetralone
- Purity
- 97%
- Packaging
- 250mg
- Price
- $39
- Updated
- 2021/12/16
6-Fluoro-1-tetralone Chemical Properties,Usage,Production
Synthesis
70631-88-8
703-67-3
General procedure for the synthesis of 6-fluoro-1-tetralone from 4-(3-fluorophenyl)butyric acid: a mixture of 4-(3-fluorophenyl)butyric acid (1.92 g, 10.5 mmol) and polyphosphoric acid (2 g) was heated under nitrogen protection at 110°C for 2 hours. After completion of the reaction, it was cooled to room temperature, the reaction was quenched with water and the reaction mixture was diluted with ether. Subsequently, it was washed with saturated aqueous sodium bicarbonate (2 times), the organic phase was dried with anhydrous sodium sulfate and concentrated to give 6-fluoro-1-tetralone (1.51 g, 87% yield). The product was characterized by NMR (400 MHz, CDCl3): δ 2.16 (m, 2H), 2.64 (t, 2H), 2.97 (t, 2H), 6.92 (dd, 1H), 6.99 (dt, 1H), 8.04 (dd, 1H).
References
[1] Patent: WO2005/92854, 2005, A1. Location in patent: Page/Page column 2
[2] Synthetic Communications, 1991, vol. 21, # 8-9, p. 981 - 987
[3] Patent: WO2006/66790, 2006, A1. Location in patent: Page/Page column 71-73
[4] Patent: WO2006/66745, 2006, A1. Location in patent: Page/Page column 21-22
[5] Patent: US2007/293526, 2007, A1. Location in patent: Page/Page column 29
6-Fluoro-1-tetralone Preparation Products And Raw materials
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View Lastest Price from 6-Fluoro-1-tetralone manufacturers
- Product
- 6-Fluortetral-1-one 703-67-3
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-31
- Product
- 6-Fluoro-1-tetralone 703-67-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 500kg
- Release date
- 2018-08-17