ChemicalBook > CAS DataBase List > N-METHOXY-N-METHYL-PROPIONAMIDE

N-METHOXY-N-METHYL-PROPIONAMIDE

Product Name: N-METHOXY-N-METHYL-PROPIONAMIDE
CAS No.: 104863-65-2
Chemical Name: N-METHOXY-N-METHYL-PROPIONAMIDE
Synonyms: N-Methyl-N-Methoxypropionamide;N-METHOXY-N-METHYL-PROPIONAMIDE;Propanamide, N-methoxy-N-methyl-
CBNumber: CB31011516
Molecular Formula: C5H11NO2
Formula Weight: 117.15
MOL File: 104863-65-2.mol

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N-METHOXY-N-METHYL-PROPIONAMIDE Property

Boiling point:: 119.0±23.0 °C(Predicted)
Density: 0.961±0.06 g/cm3(Predicted)
refractive index: 1.4270 to 1.4310
Flash point:: 26°
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: clear liquid
color: Colorless to Almost colorless
InChI: InChI=1S/C5H11NO2/c1-4-5(7)6(2)8-3/h4H2,1-3H3
InChIKey: YKVJZSZZQKQJMO-UHFFFAOYSA-N
SMILES: C(N(OC)C)(=O)CC

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Safety

RIDADR: UN 1993 3/PG III
HazardClass: 3
PackingGroup: III
HS Code: 2924190090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M3096
Product name: N-Methoxy-N-methylpropionamide
Purity: >97.0%(GC)
Packaging: 1g
Price: $54
Updated: 2025/07/31

TCI Chemical

Product number: M3096
Product name: N-Methoxy-N-methylpropionamide
Purity: >97.0%(GC)
Packaging: 5g
Price: $159
Updated: 2025/07/31

TRC

Product number: M271818
Product name: N-Methoxy-N-methylpropionamide
Packaging: 10mg
Price: $50
Updated: 2021/12/16

Oakwood

Product number: 306492
Product name: N-Methoxy-N-methylpropionamide
Packaging: 1g
Price: $27
Updated: 2021/12/16

Oakwood

Product number: 306492
Product name: N-Methoxy-N-methylpropionamide
Packaging: 5g
Price: $90
Updated: 2021/12/16

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N-METHOXY-N-METHYL-PROPIONAMIDE Chemical Properties,Usage,Production

Synthesis

6638-79-5

79-03-8

104863-65-2

Pyridine (17 mL, 0.4 mol) was slowly added dropwise to a solution of anhydrous dichloromethane (250 mL) containing O,N-dimethylhydroxylamine hydrochloride (10 g, 0.1 mol) and propionyl chloride (10 g, 0.1 mol) at 0 °C. The reaction mixture was stirred continuously for 24 hours at room temperature. Subsequently, the reaction solution was washed sequentially with 5% hydrochloric acid (2 x 50 mL), saturated sodium bicarbonate solution (100 mL) and brine (100 mL). The organic phase was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to afford the colorless oily product N-methoxy-N-methyl-propionamide (10 g, 89% yield).

References

[1] Journal of Medicinal Chemistry, 2017, vol. 60, # 12, p. 4840 - 4860
[2] Organic Letters, 2012, vol. 14, # 9, p. 2250 - 2253
[3] Chemistry - A European Journal, 2001, vol. 7, # 21, p. 4562 - 4571
[4] Patent: WO2010/104488, 2010, A1. Location in patent: Page/Page column 65
[5] Journal of Organic Chemistry, 2007, vol. 72, # 15, p. 5828 - 5831

N-METHOXY-N-METHYL-PROPIONAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-METHOXY-N-METHYL-PROPIONAMIDE Suppliers

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104863-65-2