2-Chloro-4,6-dimethyl-3-pyridinecarboxylic acid
- Product Name
- 2-Chloro-4,6-dimethyl-3-pyridinecarboxylic acid
- CAS No.
- 66662-48-4
- Chemical Name
- 2-Chloro-4,6-dimethyl-3-pyridinecarboxylic acid
- Synonyms
- 2-chloro-4,6-dimethylpyridine-3-carboxylicaci;2-chloro-4,6-dimethylpyridine-3-carboxylic acid;2-CHLORO-4,6-DIMETHYL-3-PYRIDINECARBOXYLIC ACID;3-Pyridinecarboxylic acid, 2-chloro-4,6-dimethyl-;2-Chloro-4,6-dimethyl-3-pyridinecarboxylic acid ISO 9001：2015 REACH
- CBNumber
- CB31012881
- Molecular Formula
- C8H8ClNO2
- Formula Weight
- 185.61
- MOL File
- 66662-48-4.mol
2-Chloro-4,6-dimethyl-3-pyridinecarboxylic acid Property
- Melting point:
- 139-140 °C(Solv: ethyl acetate (141-78-6))
- Boiling point:
- 342.3±37.0 °C(Predicted)
- Density
- 1.328±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 2.11±0.38(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P233Keep container tightly closed.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304IF INHALED:
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362Take off contaminated clothing and wash before reuse.
P403Store in a well-ventilated place.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C428283
- Product name
- 2-Chloro-4,6-dimethylnicotinicacid
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- C428283
- Product name
- 2-Chloro-4,6-dimethylnicotinicacid
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FC148320
- Product name
- 2-Chloro-4,6-dimethyl-3-pyridinecarboxylicacid
- Packaging
- 25mg
- Price
- $78
- Updated
- 2021/12/16
- Product number
- OR927545
- Product name
- 2-Chloro-4,6-dimethylnicotinicacid
- Purity
- 97%
- Packaging
- 1g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- FC148320
- Product name
- 2-Chloro-4,6-dimethyl-3-pyridinecarboxylicacid
- Packaging
- 50mg
- Price
- $136
- Updated
- 2021/12/16
2-Chloro-4,6-dimethyl-3-pyridinecarboxylic acid Chemical Properties,Usage,Production
Synthesis
14237-71-9
66662-48-4
Example C Synthesis of 2-chloro-4,6-dimethylnicotinic acid: 15 g of 2-chloro-3-cyano-4,6-dimethylpyridine [Jahine, J. prakt. Chem. 316, 337 (1974)] was mixed with 40 ml of concentrated sulphuric acid and 13 ml of fuming nitric acid, and heated with stirring to 95° C to initiate an exothermic reaction. The reaction temperature was maintained between 95 °C and 100 °C by cooling with ice water. After the exothermic reaction subsided, stirring was continued at 100°C for 30 minutes. Subsequently, the reaction mixture was decanted into ice and the pH was adjusted with ammonia to 3-4. The precipitate was collected by filtration and washed with water. The resulting solid was dehydrated by azeotropy with toluene in a device fitted with a water trap and finally recrystallized by toluene to give the target compound in 80% yield of the theoretical value with a melting point of 159-160°C. The results of elemental analysis were as follows: molecular formula C8H8ClNO2, molecular weight 185.6; calculated values: C 51.77%, H 4.34%, Cl 19.10%, N 7.55%; measured values: C 51.85%, H 4.36%, Cl 19.25%, N 7.56%.
References
[1] Patent: US4167570, 1979, A
[2] Chemistry of Heterocyclic Compounds, 2004, vol. 40, # 3, p. 308 - 314
2-Chloro-4,6-dimethyl-3-pyridinecarboxylic acid Preparation Products And Raw materials
Raw materials
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View Lastest Price from 2-Chloro-4,6-dimethyl-3-pyridinecarboxylic acid manufacturers
- Product
- 2-Chloro-4,6-dimethyl-3-pyridinecarboxylic acid 66662-48-4
- Price
- US $1.80/KG
- Min. Order
- 1g
- Purity
- 96%-99%
- Supply Ability
- 1kg/10kg/100kg
- Release date
- 2020-11-11
- Product
- 2-Chloro-4,6-dimethyl-3-pyridinecarboxylic acid 66662-48-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-27